Consequences of Cas9 cleavage in the chromosome of Escherichia coli

by Cui, Lun, Bikard, David
Published 2016

Editing the microbiome the CRISPR way

by Ramachandran, Gayetri, Bikard, David
Published 2019

Control of gene expression by CRISPR-Cas systems

by Bikard, David, Marraffini, Luciano A.
Published 2013

Conjugative DNA Transfer Induces the Bacterial SOS Response and Promotes Antibiotic Resistance Development through Integron Activation

by Baharoglu, Zeynep, Bikard, David, Mazel, Didier
Published 2010

Microbial defenses against mobile genetic elements and viruses: Who defends whom from what?

by Rocha, Eduardo P. C., Bikard, David
Published 2022

Improving sequence-based modeling of protein families using secondary-structure quality assessment

by Malbranke, Cyril, Bikard, David, Cocco, Simona, Monasson, Rémi
Published 2021

The synthetic integron: an in vivo genetic shuffling device

by Bikard, David, Julié-Galau, Stéphane, Cambray, Guillaume, Mazel, Didier
Published 2010

Conditional tolerance of temperate phages via transcription-dependent CRISPR-Cas targeting

by Goldberg, Gregory W., Jiang, Wenyan, Bikard, David, Marraffini, Luciano A.
Published 2014

A matter of background: DNA repair pathways as a possible cause for the sparse distribution of CRISPR-Cas systems in bacteria

by Bernheim, Aude, Bikard, David, Touchon, Marie, Rocha, Eduardo P. C.
Published 2019

Atypical organizations and epistatic interactions of CRISPRs and cas clusters in genomes and their mobile genetic elements

by Bernheim, Aude, Bikard, David, Touchon, Marie, Rocha, Eduardo P C
Published 2020

Structural Features of Single-Stranded Integron Cassette attC Sites and Their Role in Strand Selection

by Bouvier, Marie, Ducos-Galand, Magaly, Loot, Céline, Bikard, David, Mazel, Didier
Published 2009

CRISPR-assisted editing of bacterial genomes

by Jiang, Wenyan, Bikard, David, Cox, David, Zhang, Feng, Marraffini, Luciano A.
Published 2013

Tuning dCas9's ability to block transcription enables robust, noiseless knockdown of bacterial genes

by Vigouroux, Antoine, Oldewurtel, Enno, Cui, Lun, Bikard, David, van Teeffelen, Sven
Published 2018

PhageTerm: a tool for fast and accurate determination of phage termini and packaging mechanism using next-generation sequencing data

by Garneau, Julian R., Depardieu, Florence, Fortier, Louis-Charles, Bikard, David, Monot, Marc
Published 2017

A CRISPRi screen in E. coli reveals sequence-specific toxicity of dCas9

by Cui, Lun, Vigouroux, Antoine, Rousset, François, Varet, Hugo, Khanna, Varun, Bikard, David
Published 2018

Genome-wide CRISPR-dCas9 screens in E. coli identify essential genes and phage host factors

by Rousset, François, Cui, Lun, Siouve, Elise, Becavin, Christophe, Depardieu, Florence, Bikard, David
Published 2018

Programmable repression and activation of bacterial gene expression using an engineered CRISPR-Cas system

by Bikard, David, Jiang, Wenyan, Samai, Poulami, Hochschild, Ann, Zhang, Feng, Marraffini, Luciano A.
Published 2013

Generating functional protein variants with variational autoencoders

by Hawkins-Hooker, Alex, Depardieu, Florence, Baur, Sebastien, Couairon, Guillaume, Chen, Arthur, Bikard, David
Published 2021

On-target activity predictions enable improved CRISPR–dCas9 screens in bacteria

by Calvo-Villamañán, Alicia, Ng, Jérome Wong, Planel, Rémi, Ménager, Hervé, Chen, Arthur, Cui, Lun, Bikard, David
Published 2020

Cas9 off-target binding to the promoter of bacterial genes leads to silencing and toxicity

by Rostain, William, Grebert, Theophile, Vyhovskyi, Danylo, Pizarro, Paula Thiel, Tshinsele-Van Bellingen, Gatwa, Cui, Lun, Bikard, David
Published 2023