Unpicking neurodegeneration in a dish with human pluripotent stem cells: One cell type at a time

por Bilican, Bilada, Serio, Andrea, Shaw, Christopher E, Maniatis, Tom, Chandran, Siddharthan
Publicado 2013

Induction of Olig2(+) Precursors by FGF Involves BMP Signalling Blockade at the Smad Level

por Bilican, Bilada, Fiore-Heriche, Christelle, Compston, Alastair, Allen, Nicholas D., Chandran, Siddharthan
Publicado 2008

High Yields of Oligodendrocyte Lineage Cells from Human Embryonic Stem Cells at Physiological Oxygen Tensions for Evaluation of Translational Biology

por Stacpoole, Sybil R.L., Spitzer, Sonia, Bilican, Bilada, Compston, Alastair, Karadottir, Ragnhildur, Chandran, Siddharthan, Franklin, Robin J.M.
Publicado 2013

Physiological Normoxia and Absence of EGF Is Required for the Long-Term Propagation of Anterior Neural Precursors from Human Pluripotent Cells

por Bilican, Bilada, Livesey, Matthew R., Haghi, Ghazal, Qiu, Jing, Burr, Karen, Siller, Rick, Hardingham, Giles E., Wyllie, David J. A., Chandran, Siddharthan
Publicado 2014

Autophagy induction enhances TDP43 turnover and survival in neuronal ALS models

por Barmada, Sami J., Serio, Andrea, Arjun, Arpana, Bilican, Bilada, Daub, Aaron, Ando, D. Michael, Tsvetkov, Andrey, Pleiss, Michael, Li, Xingli, Peisach, Daniel, Shaw, Christopher, Chandran, Siddharthan, Finkbeiner, Steven
Publicado 2014

Ionotropic GABA and glycine receptor subunit composition in human pluripotent stem cell-derived excitatory cortical neurones

por James, Owain T, Livesey, Matthew R, Qiu, Jing, Dando, Owen, Bilican, Bilada, Haghi, Ghazal, Rajan, Rinku, Burr, Karen, Hardingham, Giles E, Chandran, Siddharthan, Kind, Peter C, Wyllie, David J A
Publicado 2014

CellSIUS provides sensitive and specific detection of rare cell populations from complex single-cell RNA-seq data

por Wegmann, Rebekka, Neri, Marilisa, Schuierer, Sven, Bilican, Bilada, Hartkopf, Huyen, Nigsch, Florian, Mapa, Felipa, Waldt, Annick, Cuttat, Rachel, Salick, Max R., Raymond, Joe, Kaykas, Ajamete, Roma, Guglielmo, Keller, Caroline Gubser
Publicado 2019

Allele-Specific Knockdown of ALS-Associated Mutant TDP-43 in Neural Stem Cells Derived from Induced Pluripotent Stem Cells

por Nishimura, Agnes L., Shum, Carole, Scotter, Emma L., Abdelgany, Amr, Sardone, Valentina, Wright, Jamie, Lee, Youn-Bok, Chen, Han-Jou, Bilican, Bilada, Carrasco, Monica, Maniatis, Tom, Chandran, Siddharthan, Rogelj, Boris, Gallo, Jean-Marc, Shaw, Christopher E.
Publicado 2014

Evidence for evolutionary divergence of activity-dependent gene expression in developing neurons

por Qiu, Jing, McQueen, Jamie, Bilican, Bilada, Dando, Owen, Magnani, Dario, Punovuori, Karolina, Selvaraj, Bhuvaneish T, Livesey, Matthew, Haghi, Ghazal, Heron, Samuel, Burr, Karen, Patani, Rickie, Rajan, Rinku, Sheppard, Olivia, Kind, Peter C, Simpson, T Ian, Tybulewicz, Victor LJ, Wyllie, David JA, Fisher, Elizabeth MC, Lowell, Sally, Chandran, Siddharthan, Hardingham, Giles E
Publicado 2016

Neuronal development is promoted by weakened intrinsic antioxidant defences due to epigenetic repression of Nrf2

por Bell, Karen F.S., Al-Mubarak, Bashayer, Martel, Marc-André, McKay, Sean, Wheelan, Nicola, Hasel, Philip, Márkus, Nóra M., Baxter, Paul, Deighton, Ruth F., Serio, Andrea, Bilican, Bilada, Chowdhry, Sudhir, Meakin, Paul J., Ashford, Michael L.J., Wyllie, David J.A., Scannevin, Robert H., Chandran, Siddharthan, Hayes, John D., Hardingham, Giles E.
Publicado 2015

A proteogenomic view of Parkinson’s disease causality and heterogeneity

por Kaiser, Sergio, Zhang, Luqing, Mollenhauer, Brit, Jacob, Jaison, Longerich, Simonne, Del-Aguila, Jorge, Marcus, Jacob, Raghavan, Neha, Stone, David, Fagboyegun, Olumide, Galasko, Douglas, Dakna, Mohammed, Bilican, Bilada, Dovlatyan, Mary, Kostikova, Anna, Li, Jingyao, Peterson, Brant, Rotte, Michael, Sanz, Vinicius, Foroud, Tatiana, Hutten, Samantha J., Frasier, Mark, Iwaki, Hirotaka, Singleton, Andrew, Marek, Ken, Crawford, Karen, Elwood, Fiona, Messa, Mirko, Serrano-Fernandez, Pablo
Publicado 2023

Human genetics uncovers MAP3K15 as an obesity-independent therapeutic target for diabetes

por Nag, Abhishek, Dhindsa, Ryan S., Mitchell, Jonathan, Vasavda, Chirag, Harper, Andrew R., Vitsios, Dimitrios, Ahnmark, Andrea, Bilican, Bilada, Madeyski-Bengtson, Katja, Zarrouki, Bader, Zoghbi, Anthony W., Wang, Quanli, Smith, Katherine R., Alegre-Díaz, Jesus, Kuri-Morales, Pablo, Berumen, Jaime, Tapia-Conyer, Roberto, Emberson, Jonathan, Torres, Jason M., Collins, Rory, Smith, David M., Challis, Benjamin, Paul, Dirk S., Bohlooly-Y, Mohammad, Snowden, Mike, Baker, David, Fritsche-Danielson, Regina, Pangalos, Menelas N., Petrovski, Slavé
Publicado 2022