An optimized thermodynamics integration protocol for identifying beneficial mutations in antibody design

por Sheng, Zizhang, Bimela, Jude S., Wang, Maple, Li, Zhiteng, Guo, Yicheng, Ho, David D.
Publicado 2023

Antiretroviral Imprints and Genomic Plasticity of HIV-1 pol in Non-clade B: Implications for Treatment

por Bimela, Jude S., Nanfack, Aubin J., Yang, Pengpeng, Dai, Shaoxing, Kong, Xiang-Peng, Torimiro, Judith N., Duerr, Ralf
Publicado 2022

Structural Basis of Antibody Conformation and Stability Modulation by Framework Somatic Hypermutation

por Sheng, Zizhang, Bimela, Jude S., Katsamba, Phinikoula S., Patel, Saurabh D., Guo, Yicheng, Zhao, Haiqing, Guo, Youzhong, Kwong, Peter D., Shapiro, Lawrence
Publicado 2022

Affinity requirements for control of synaptic targeting and neuronal cell survival by heterophilic IgSF cell adhesion molecules

por Xu, Shuwa, Sergeeva, Alina P., Katsamba, Phinikoula S., Mannepalli, Seetha, Bahna, Fabiana, Bimela, Jude, Zipursky, S. Lawrence, Shapiro, Lawrence, Honig, Barry, Zinn, Kai
Publicado 2022

Structural basis for accommodation of emerging B.1.351 and B.1.1.7 variants by two potent SARS-CoV-2 neutralizing antibodies

por Cerutti, Gabriele, Rapp, Micah, Guo, Yicheng, Bahna, Fabiana, Bimela, Jude, Reddem, Eswar R., Yu, Jian, Wang, Pengfei, Liu, Lihong, Huang, Yaoxing, Ho, David D., Kwong, Peter D., Sheng, Zizhang, Shapiro, Lawrence
Publicado 2021

Development of a Versatile, Near Full Genome Amplification and Sequencing Approach for a Broad Variety of HIV-1 Group M Variants

por Banin, Andrew N., Tuen, Michael, Bimela, Jude S., Tongo, Marcel, Zappile, Paul, Khodadadi-Jamayran, Alireza, Nanfack, Aubin J., Meli, Josephine, Wang, Xiaohong, Mbanya, Dora, Ngogang, Jeanne, Heguy, Adriana, Nyambi, Phillipe N., Fokunang, Charles, Duerr, Ralf
Publicado 2019

Near full genome characterization of HIV‐1 unique recombinant forms in Cameroon reveals dominant CRF02_AG and F2 recombination patterns

por Banin, Andrew N, Tuen, Michael, Bimela, Jude S, Tongo, Marcel, Zappile, Paul, Khodadadi‐Jamayran, Alireza, Nanfack, Aubin J, Okonko, Iheanyi O, Meli, Josephine, Wang, Xiaohong, Mbanya, Dora, Ngogang, Jeanne, Gorny, Miroslaw K, Heguy, Adriana, Fokunang, Charles, Duerr, Ralf
Publicado 2019

Modular basis for potent SARS-CoV-2 neutralization by a prevalent VH1-2-derived antibody class

por Rapp, Micah, Guo, Yicheng, Reddem, Eswar R., Yu, Jian, Liu, Lihong, Wang, Pengfei, Cerutti, Gabriele, Katsamba, Phinikoula, Bimela, Jude S., Bahna, Fabiana A., Mannepalli, Seetha M., Zhang, Baoshan, Kwong, Peter D., Huang, Yaoxing, Ho, David D., Shapiro, Lawrence, Sheng, Zizhang
Publicado 2021

Potent SARS-CoV-2 neutralizing antibodies directed against spike N-terminal domain target a single supersite

por Cerutti, Gabriele, Guo, Yicheng, Zhou, Tongqing, Gorman, Jason, Lee, Myungjin, Rapp, Micah, Reddem, Eswar R., Yu, Jian, Bahna, Fabiana, Bimela, Jude, Huang, Yaoxing, Katsamba, Phinikoula S., Liu, Lihong, Nair, Manoj S., Rawi, Reda, Olia, Adam S., Wang, Pengfei, Zhang, Baoshan, Chuang, Gwo-Yu, Ho, David D., Sheng, Zizhang, Kwong, Peter D., Shapiro, Lawrence
Publicado 2021

Cryo-EM Structures of SARS-CoV-2 Spike without and with ACE2 Reveal a pH-Dependent Switch to Mediate Endosomal Positioning of Receptor-Binding Domains

por Zhou, Tongqing, Tsybovsky, Yaroslav, Gorman, Jason, Rapp, Micah, Cerutti, Gabriele, Chuang, Gwo-Yu, Katsamba, Phinikoula S., Sampson, Jared M., Schön, Arne, Bimela, Jude, Boyington, Jeffrey C., Nazzari, Alexandra, Olia, Adam S., Shi, Wei, Sastry, Mallika, Stephens, Tyler, Stuckey, Jonathan, Teng, I-Ting, Wang, Pengfei, Wang, Shuishu, Zhang, Baoshan, Friesner, Richard A., Ho, David D., Mascola, John R., Shapiro, Lawrence, Kwong, Peter D.
Publicado 2020

Immune Correlates of Disease Progression in Linked HIV-1 Infection

por Tuen, Michael, Bimela, Jude S., Banin, Andrew N., Ding, Shilei, Harkins, Gordon W., Weiss, Svenja, Itri, Vincenza, Durham, Allison R., Porcella, Stephen F., Soni, Sonal, Mayr, Luzia, Meli, Josephine, Torimiro, Judith N., Tongo, Marcel, Wang, Xiaohong, Kong, Xiang-Peng, Nádas, Arthur, Kaufmann, Daniel E., Brumme, Zabrina L., Nanfack, Aubin J., Quinn, Thomas C., Zolla-Pazner, Susan, Redd, Andrew D., Finzi, Andrés, Gorny, Miroslaw K., Nyambi, Phillipe N., Duerr, Ralf
Publicado 2019

Paired heavy- and light-chain signatures contribute to potent SARS-CoV-2 neutralization in public antibody responses

por Banach, Bailey B., Cerutti, Gabriele, Fahad, Ahmed S., Shen, Chen-Hsiang, Oliveira De Souza, Matheus, Katsamba, Phinikoula S., Tsybovsky, Yaroslav, Wang, Pengfei, Nair, Manoj S., Huang, Yaoxing, Francino-Urdániz, Irene M., Steiner, Paul J., Gutiérrez-González, Matías, Liu, Lihong, López Acevedo, Sheila N., Nazzari, Alexandra F., Wolfe, Jacy R., Luo, Yang, Olia, Adam S., Teng, I-Ting, Yu, Jian, Zhou, Tongqing, Reddem, Eswar R., Bimela, Jude, Pan, Xiaoli, Madan, Bharat, Laflin, Amy D., Nimrania, Rajani, Yuen, Kwok-Yung, Whitehead, Timothy A., Ho, David D., Kwong, Peter D., Shapiro, Lawrence, DeKosky, Brandon J.
Publicado 2021