DNA damage-induced interaction between a lineage addiction oncogenic transcription factor and the MRN complex shapes a tissue-specific DNA Damage Response and cancer predisposition

por Binet, Romuald, Lambert, Jean-Philippe, Tomkova, Marketa, Tischfield, Samuel, Baggiolini, Arianna, Picaud, Sarah, Sarkar, Sovan, Louphrasitthiphol, Pakavarin, Dias, Diogo, Carreira, Suzanne, Humphrey, Timothy, Fillipakopoulos, Panagis, White, Richard, Goding, Colin R
Publicado 2023

BRN2 suppresses apoptosis, reprograms DNA damage repair, and is associated with a high somatic mutation burden in melanoma

por Herbert, Katharine, Binet, Romuald, Lambert, Jean-Philippe, Louphrasitthiphol, Pakavarin, Kalkavan, Halime, Sesma-Sanz, Laura, Robles-Espinoza, Carla Daniela, Sarkar, Sovan, Suer, Eda, Andrews, Sarah, Chauhan, Jagat, Roberts, Nicola D., Middleton, Mark R., Gingras, Anne-Claude, Masson, Jean-Yves, Larue, Lionel, Falletta, Paola, Goding, Colin R.
Publicado 2019