Hydrocarbon-Stapled Peptides: Principles, Practice, and Progress: Miniperspective

por Walensky, Loren D., Bird, Gregory H.
Publicado 2014

Characterization of a core fragment of the rhesus monkey TRIM5α protein

por Kar, Alak K, Mao, Youdong, Bird, Gregory, Walensky, Loren, Sodroski, Joseph
Publicado 2011

Mechanistic Validation of a Clinical Lead Stapled Peptide that Reactivates p53 by Dual HDM2 and HDMX Targeting

por Wachter, Franziska, Morgan, Ann M., Godes, Marina, Mourtada, Rida, Bird, Gregory H., Walensky, Loren D.
Publicado 2016

A redox switch regulates the structure and function of anti-apoptotic BFL-1

por Korshavn, Kyle J., Wales, Thomas E., Bird, Gregory H., Engen, John R., Walensky, Loren D.
Publicado 2020

Stapled HIV-1 Peptides Recapitulate Antigenic Structures and Engage Broadly Neutralizing Antibodies

por Bird, Gregory H., Irimia, Adriana, Ofek, Gilad, Kwong, Peter D., Wilson, Ian A., Walensky, Loren D.
Publicado 2014

Targeted Disruption of the EZH2/EED Complex Inhibits EZH2-dependent Cancer

por Kim, Woojin, Bird, Gregory H., Neff, Tobias, Guo, Guoji, Kerenyi, Marc A., Walensky, Loren D., Orkin, Stuart H.
Publicado 2013

Biophysical Determinants for Cellular Uptake of Hydrocarbon-Stapled Peptide Helices

por Bird, Gregory H., Mazzola, Emanuele, Opoku-Nsiah, Kwadwo, Lammert, Margaret A., Godes, Marina, Neuberg, Donna S., Walensky, Loren D.
Publicado 2016

Expansion of Human and Murine Hematopoietic Stem and Progenitor Cells Ex Vivo without Genetic Modification Using MYC and Bcl-2 Fusion Proteins

por Bird, Gregory A., Polsky, Avital, Estes, Patricia, Hanlon, Teri, Hamilton, Haley, Morton, John J., Gutman, Jonathan, Jimeno, Antonio, Turner, Brian C., Refaeli, Yosef
Publicado 2014

Allosteric Inhibition of Anti-Apoptotic MCL-1

por Lee, Susan, Wales, Thomas E., Escudero, Silvia, Cohen, Daniel T., Luccarelli, James, Gallagher, Catherine, Cohen, Nicole A., Huhn, Annissa J., Bird, Gregory H., Engen, John R., Walensky, Loren D.
Publicado 2016

BAX Activation is Initiated at a Novel Interaction Site

por Gavathiotis, Evripidis, Suzuki, Motoshi, Davis, Marguerite L., Pitter, Kenneth, Bird, Gregory H., Katz, Samuel G., Tu, Ho-Chou, Kim, Hyungjin, Cheng, Emily H.-Y., Tjandra, Nico, Walensky, Loren D.
Publicado 2008

Inhibition of FOXP3 by stapled alpha-helical peptides dampens regulatory T cell function

por Hawley, Katrina M., Eclov, Rachel J., Schnorenberg, Mathew R., Tian, Yu, Shah, Rhea N., Thomas-Toth, Anika T., Fefferman, Marie, Bird, Gregory H., Walensky, Loren D., Tirrell, Matthew V., LaBelle, James L.
Publicado 2022

Targeting a Helix-in-Groove Interaction Between E1 and E2 Blocks Ubiquitin Transfer

por Cathcart, Ann M., Bird, Gregory H., Wales, Thomas E., Herce, Henry D., Harvey, Edward P., Hauseman, Zachary J., Newman, Catherine E., Adhikary, Utsarga, Prew, Michelle S., Oo, Tun, Lee, Susan, Engen, John R., Walensky, Loren D.
Publicado 2020

Preventive and therapeutic effects of Smad7 on radiation-induced oral mucositis

por Han, Gangwen, Bian, Li, Li, Fulun, Cotrim, Ana, Wang, Donna, Lu, Jian Bo, Deng, Yu, Bird, Gregory, Sowers, Anastasia, Mitchell, James B., Gutkind, J. Silvio, Zhao, Rui, Raben, David, Dijke, Peter ten, Refaeli, Yosef, Zhang, Qinghong, Wang, Xiao-Jing
Publicado 2013

Genome-scale CRISPR-Cas9 screen identifies druggable dependencies in TP53 wild-type Ewing sarcoma

por Stolte, Björn, Iniguez, Amanda Balboni, Dharia, Neekesh V., Robichaud, Amanda L., Conway, Amy Saur, Morgan, Ann M., Alexe, Gabriela, Schauer, Nathan J., Liu, Xiaoxi, Bird, Gregory H., Tsherniak, Aviad, Vazquez, Francisca, Buhrlage, Sara J., Walensky, Loren D., Stegmaier, Kimberly
Publicado 2018

Structural basis for defective membrane targeting of mutant enzyme in human VLCAD deficiency

por Prew, Michelle S., Camara, Christina M., Botzanowski, Thomas, Moroco, Jamie A., Bloch, Noah B., Levy, Hannah R., Seo, Hyuk-Soo, Dhe-Paganon, Sirano, Bird, Gregory H., Herce, Henry D., Gygi, Micah A., Escudero, Silvia, Wales, Thomas E., Engen, John R., Walensky, Loren D.
Publicado 2022

Binding and transport of SFPQ-RNA granules by KIF5A/KLC1 motors promotes axon survival

por Fukuda, Yusuke, Pazyra-Murphy, Maria F., Silagi, Elizabeth S., Tasdemir-Yilmaz, Ozge E., Li, Yihang, Rose, Lillian, Yeoh, Zoe C., Vangos, Nicholas E., Geffken, Ezekiel A., Seo, Hyuk-Soo, Adelmant, Guillaume, Bird, Gregory H., Walensky, Loren D., Marto, Jarrod A., Dhe-Paganon, Sirano, Segal, Rosalind A.
Publicado 2020

Repression of BIM mediates survival signaling by MYC and AKT in high-risk T-cell acute lymphoblastic leukemia

por Reynolds, Christine, Roderick, Justine E., LaBelle, James L., Bird, Gregory, Mathieu, Ronald, Bodaar, Kimberly, Colon, Diana, Pyati, Ujwal, Stevenson, Kristen E., Qi, Jun, Harris, Marian, Silverman, Lewis B., Sallan, Stephen E., Bradner, James E., Neuberg, Donna S., Look, A. Thomas, Walensky, Loren D., Kelliher, Michelle A., Gutierrez, Alejandro
Publicado 2014

XactMice: humanizing mouse bone marrow enables microenvironment reconstitution in a patient-derived xenograft model of head and neck cancer

por Morton, J. Jason, Bird, Gregory, Keysar, Stephen B., Astling, David P., Lyons, Traci R, Anderson, Ryan T., Glogowska, Magdalena J., Estes, Patricia, Eagles, Justin R., Le, Phuong N., Gan, Gregory, McGettigan, Brett, Fernandez, Pamela, Padilla-Just, Nuria, Varella-Garcia, Marileila, Song, John I., Bowles, Daniel W., Schedin, Pepper, Tan, Aik-Choon, Roop, Dennis R., Wang, Xiao-Jing, Refaeli, Yosef, Jimeno, Antonio
Publicado 2015

Glucose-dependent partitioning of arginine to the urea cycle protects β-cells from inflammation

por Fu, Accalia, Alvarez-Perez, Juan Carlos, Avizonis, Daina, Kin, Tatsuya, Ficarro, Scott B., Choi, Dong Wook, Karakose, Esra, Badur, Mehmet G., Evans, Lindsay, Rosselot, Carolina, Bridon, Gaelle, Bird, Gregory H., Seo, Hyuk-Soo, Dhe-Paganon, Sirano, Kamphorst, Jurre J., Stewart, Andrew F., Shapiro, A. M. James, Marto, Jarrod A., Walensky, Loren D., Jones, Russell G., Garcia-Ocana, Adolfo, Danial, Nika N.
Publicado 2020