Therapy drives genomic evolution in metastatic cancer

por Christensen, Ditte S., Birkbak, Nicolai J.
Publicado 2023

Jetset: selecting the optimal microarray probe set to represent a gene

por Li, Qiyuan, Birkbak, Nicolai J, Gyorffy, Balazs, Szallasi, Zoltan, Eklund, Aron C
Publicado 2011

Computational Analysis Reveals the Temporal Acquisition of Pathway Alterations during the Evolution of Cancer

por Ahrenfeldt, Johanne, Christensen, Ditte S., Sokač, Mateo, Kisistók, Judit, McGranahan, Nicholas, Birkbak, Nicolai J.
Publicado 2022

The ratio of adaptive to innate immune cells differs between genders and associates with improved prognosis and response to immunotherapy

por Ahrenfeldt, Johanne, Christensen, Ditte S., Østergaard, Andreas B., Kisistók, Judit, Sokač, Mateo, Birkbak, Nicolai J.
Publicado 2023

Spatial transformation of multi-omics data unlocks novel insights into cancer biology

por Sokač, Mateo, Kjær, Asbjørn, Dyrskjøt, Lars, Haibe-Kains, Benjamin, JWL Aerts, Hugo, Birkbak, Nicolai J
Publicado 2023

A breast cancer meta-analysis of two expression measures of chromosomal instability reveals a relationship with younger age at diagnosis and high risk histopathological variables

por Endesfelder, David, McGranahan, Nicholas, Birkbak, Nicolai J., Szallasi, Zoltan, Kschischo, Maik, Graham, Trevor A., Swanton, Charles
Publicado 2011

Classifying cGAS-STING Activity Links Chromosomal Instability with Immunotherapy Response in Metastatic Bladder Cancer

por Sokač, Mateo, Ahrenfeldt, Johanne, Litchfield, Kevin, Watkins, Thomas B.K., Knudsen, Michael, Dyrskjøt, Lars, Jakobsen, Martin R., Birkbak, Nicolai J.
Publicado 2022

Migrating the SNP array-based homologous recombination deficiency measures to next generation sequencing data of breast cancer

por Sztupinszki, Zsofia, Diossy, Miklos, Krzystanek, Marcin, Reiniger, Lilla, Csabai, István, Favero, Francesco, Birkbak, Nicolai J., Eklund, Aron C., Syed, Ali, Szallasi, Zoltan
Publicado 2018

Foundation Models for Quantitative Biomarker Discovery in Cancer Imaging

por Pai, Suraj, Bontempi, Dennis, Prudente, Vasco, Hadzic, Ibrahim, Sokač, Mateo, Chaunzwa, Tafadzwa L., Bernatz, Simon, Hosny, Ahmed, Mak, Raymond H, Birkbak, Nicolai J, Aerts, Hugo JWL
Publicado 2023

Pan-cancer analysis of genomic scar signatures associated with homologous recombination deficiency suggests novel indications for existing cancer drugs

por Marquard, Andrea M, Eklund, Aron C, Joshi, Tejal, Krzystanek, Marcin, Favero, Francesco, Wang, Zhigang C, Richardson, Andrea L, Silver, Daniel P, Szallasi, Zoltan, Birkbak, Nicolai J
Publicado 2015

Consistent metagenes from cancer expression profiles yield agent specific predictors of chemotherapy response

por Li, Qiyuan, Eklund, Aron C, Birkbak, Nicolai J, Desmedt, Christine, Haibe-Kains, Benjamin, Sotiriou, Christos, Symmans, W Fraser, Pusztai, Lajos, Brunak, Søren, Richardson, Andrea L, Szallasi, Zoltan
Publicado 2011

Allele-Specific HLA Loss and Immune Escape in Lung Cancer Evolution

por McGranahan, Nicholas, Rosenthal, Rachel, Hiley, Crispin T., Rowan, Andrew J., Watkins, Thomas B.K., Wilson, Gareth A., Birkbak, Nicolai J., Veeriah, Selvaraju, Van Loo, Peter, Herrero, Javier, Swanton, Charles
Publicado 2017

Genomic instability in mutant p53 cancer cells upon entotic engulfment

por Mackay, Hannah L., Moore, David, Hall, Callum, Birkbak, Nicolai J., Jamal-Hanjani, Mariam, Karim, Saadia A., Phatak, Vinaya M., Piñon, Lucia, Morton, Jennifer P., Swanton, Charles, Le Quesne, John, Muller, Patricia A. J.
Publicado 2018

Publisher Correction: Genomic instability in mutant p53 cancer cells upon entotic engulfment

por Mackay, Hannah L., Moore, David, Hall, Callum, Birkbak, Nicolai J., Jamal-Hanjani, Mariam, Karim, Saadia A., Phatak, Vinaya M., Piñon, Lucia, Morton, Jennifer P., Swanton, Charles, Le Quesne, John, Muller, Patricia A. J.
Publicado 2018

HELQ promotes RAD51 paralog-dependent repair to avert germ cell attrition and tumourigenesis

por Adelman, Carrie A., Lolo, Rafal L., Birkbak, Nicolai J., Murina, Olga, Matsuzaki, Kenichiro, Horejsi, Zuzana, Parmar, Kalindi, Borel, Valérie, Skehel, J. Mark, Stamp, Gordon, D’Andrea, Alan, Sartori, Alessandro A., Swanton, Charles, Boulton, Simon J.
Publicado 2013

Revisiting inconsistency in large pharmacogenomic studies

por Safikhani, Zhaleh, Smirnov, Petr, Freeman, Mark, El-Hachem, Nehme, She, Adrian, Rene, Quevedo, Goldenberg, Anna, Birkbak, Nicolai J., Hatzis, Christos, Shi, Leming, Beck, Andrew H., Aerts, Hugo J.W.L., Quackenbush, John, Haibe-Kains, Benjamin
Publicado 2017

Impact of Whole Genome Doubling on Detection of Circulating Tumor DNA in Colorectal Cancer

por Kabel, Jonas, Henriksen, Tenna Vesterman, Demuth, Christina, Frydendahl, Amanda, Rasmussen, Mads Heilskov, Nors, Jesper, Birkbak, Nicolai J., Madsen, Anders Husted, Løve, Uffe S., Andersen, Per Vadgaard, Kolbro, Thomas, Monti, Alessio, Thorlacius-Ussing, Ole, Gögenur, Mikail, Kildsig, Jeppe, Schlesinger, Nis Hallundbæk, Bondeven, Peter, Iversen, Lene Hjerrild, Gotschalck, Kåre Andersson, Andersen, Claus Lindbjerg
Publicado 2023

Artificial intelligence in cancer imaging: Clinical challenges and applications

por Bi, Wenya Linda, Hosny, Ahmed, Schabath, Matthew B., Giger, Maryellen L., Birkbak, Nicolai J., Mehrtash, Alireza, Allison, Tavis, Arnaout, Omar, Abbosh, Christopher, Dunn, Ian F., Mak, Raymond H., Tamimi, Rulla M., Tempany, Clare M., Swanton, Charles, Hoffmann, Udo, Schwartz, Lawrence H., Gillies, Robert J., Huang, Raymond Y., Aerts, Hugo J. W. L.
Publicado 2019

Oncogenic PIK3CA induces centrosome amplification and tolerance to genome doubling

por Berenjeno, Inma M., Piñeiro, Roberto, Castillo, Sandra D., Pearce, Wayne, McGranahan, Nicholas, Dewhurst, Sally M., Meniel, Valerie, Birkbak, Nicolai J., Lau, Evelyn, Sansregret, Laurent, Morelli, Daniele, Kanu, Nnennaya, Srinivas, Shankar, Graupera, Mariona, Parker, Victoria E. R., Montgomery, Karen G., Moniz, Larissa S., Scudamore, Cheryl L., Phillips, Wayne A., Semple, Robert K., Clarke, Alan, Swanton, Charles, Vanhaesebroeck, Bart
Publicado 2017

Evolution and clinical impact of co-occurring genetic alterations in advanced-stage EGFR-mutant lung cancers

por Blakely, Collin M., Watkins, Thomas B.K., Wu, Wei, Gini, Beatrice, Chabon, Jacob J., McCoach, Caroline E., McGranahan, Nicholas, Wilson, Gareth A., Birkbak, Nicolai J., Olivas, Victor R., Rotow, Julia, Maynard, Ashley, Wang, Victoria, Gubens, Matthew A., Banks, Kimberly C., Lanman, Richard B., Caulin, Aleah F., John, John St., Cordero, Anibal R., Giannikopoulos, Petros, Simmons, Andrew D., Mack, Philip C., Gandara, David R., Husain, Hatim, Doebele, Robert C., Riess, Jonathan W., Diehn, Maximilian, Swanton, Charles, Bivona, Trever G.
Publicado 2017