The histone demethylase KDM3A, and its downstream target MCAM, promote Ewing Sarcoma cell migration and metastasis

por Sechler, Marybeth, Parrish, Janet K., Birks, Diane K., Jedlicka, Paul
Publicado 2017

Unique Molecular Characteristics of Pediatric Myxopapillary Ependymoma

por Barton, Valerie N., Donson, Andrew M., Kleinschmidt‐DeMasters, Bette K., Birks, Diane K., Handler, Michael H., Foreman, Nicholas K.
Publicado 2009

MPS1 kinase as a potential therapeutic target in medulloblastoma

por Alimova, Irina, Ng, June, Harris, Peter, Birks, Diane, Donson, Andrew, Taylor, Michael D., Foreman, Nicholas K., Venkataraman, Sujatha, Vibhakar, Rajeev
Publicado 2016

Polo-like kinase 1 (PLK1) inhibition suppresses cell growth and enhances radiation sensitivity in medulloblastoma cells

por Harris, Peter S, Venkataraman, Sujatha, Alimova, Irina, Birks, Diane K, Donson, Andrew M, Knipstein, Jeffrey, Dubuc, Adrian, Taylor, Michael D, Handler, Michael H, Foreman, Nicholas K, Vibhakar, Rajeev
Publicado 2012

Targeting Polo-like kinase 1 in SMARCB1 deleted atypical teratoid rhabdoid tumor

por Alimova, Irina, Pierce, Angela M., Harris, Peter, Donson, Andrew, Birks, Diane K., Prince, Eric, Balakrishnan, Ilango, Foreman, Nicholas K., Kool, Marcel, Hoffman, Lindsey, Venkataraman, Sujatha, Vibhakar, Rajeev
Publicado 2017

Microrna expression signatures predict patient progression and disease outcome in pediatric embryonal central nervous system neoplasms

por Braoudaki, Maria, Lambrou, George I, Giannikou, Krinio, Milionis, Vasilis, Stefanaki, Kalliopi, Birks, Diane K, Prodromou, Neophytos, Kolialexi, Aggeliki, Kattamis, Antonis, Spiliopoulou, Chara A, Tzortzatou-Stathopoulou, Fotini, Kanavakis, Emmanouel
Publicado 2014

Exosomal microRNA profiling to identify hypoxia-related biomarkers in prostate cancer

por Panigrahi, Gati K., Ramteke, Anand, Birks, Diane, Abouzeid Ali, Hamdy E., Venkataraman, Sujatha, Agarwal, Chapla, Vibhakar, Rajeev, Miller, Lance D., Agarwal, Rajesh, Abd Elmageed, Zakaria Y., Deep, Gagan
Publicado 2018

Integrated genomic analysis identifies the mitotic checkpoint kinase WEE1 as a novel therapeutic target in medulloblastoma

por Harris, Peter S, Venkataraman, Sujatha, Alimova, Irina, Birks, Diane K, Balakrishnan, Ilango, Cristiano, Brian, Donson, Andrew M, Dubuc, Adrian M, Taylor, Michael D, Foreman, Nicholas K, Reigan, Philip, Vibhakar, Rajeev
Publicado 2014

Inhibition of BRD4 attenuates tumor cell self-renewal and suppresses stem cell signaling in MYC driven medulloblastoma

por Venkataraman, Sujatha, Alimova, Irina, Balakrishnan, Ilango, Harris, Peter, Birks, Diane K, Griesinger, Andrea, Amani, Vladimir, Cristiano, Brian, Remke, Marc, Taylor, Michael D, Handler, Michael, Foreman, Nicholas K, Vibhakar, Rajeev
Publicado 2014

Polo-like Kinase 1 as a potential therapeutic target in Diffuse Intrinsic Pontine Glioma

por Amani, Vladimir, Prince, Eric W, Alimova, Irina, Balakrishnan, Ilango, Birks, Diane, Donson, Andrew M., Harris, Peter, Levy, Jean M. Mulcahy, Handler, Michael, Foreman, Nicholas K., Venkataraman, Sujatha, Vibhakar, Rajeev
Publicado 2016

Identification of targets for rational pharmacological therapy in childhood craniopharyngioma

por Gump, Jacob M., Donson, Andrew M., Birks, Diane K., Amani, Vladimir M., Rao, Karun K., Griesinger, Andrea M., Kleinschmidt-DeMasters, B. K., Johnston, James M., Anderson, Richard C. E., Rosenfeld, Amy, Handler, Michael, Gore, Lia, Foreman, Nicholas, Hankinson, Todd C.
Publicado 2015

Checkpoint kinase 1 expression is an adverse prognostic marker and therapeutic target in MYC-driven medulloblastoma

por Prince, Eric W., Balakrishnan, Ilango, Shah, Monil, Mulcahy Levy, Jean M., Griesinger, Andrea M., Alimova, Irina, Harris, Peter S., Birks, Diane K., Donson, Andrew M., Davidson, Nathan, Remke, Marc, Taylor, Michael D., Handler, Michael H., Foreman, Nicholas K., Venkataraman, Sujatha, Vibhakar, Rajeev
Publicado 2016

Autophagy inhibition overcomes multiple mechanisms of resistance to BRAF inhibition in brain tumors

por Mulcahy Levy, Jean M, Zahedi, Shadi, Griesinger, Andrea M, Morin, Andrew, Davies, Kurtis D, Aisner, Dara L, Kleinschmidt-DeMasters, BK, Fitzwalter, Brent E, Goodall, Megan L, Thorburn, Jacqueline, Amani, Vladimir, Donson, Andrew M, Birks, Diane K, Mirsky, David M, Hankinson, Todd C, Handler, Michael H, Green, Adam L, Vibhakar, Rajeev, Foreman, Nicholas K, Thorburn, Andrew
Publicado 2017

DIPG-73. SENESCENCE ASSOCIATED SECRETORY PHENOTYPE AS A MECHANISM OF RESISTANCE AND THERAPEUTIC VULNERABILITY IN BMI1 INHIBITOR TREATED DIPG

por Balakrishnan, Ilango, Danis, Etienne, Pierce, Angela, Madhavan, Krishna, Wang, Dong, Dahl, Nathan, Bridget, Sanford, Birks, Diane K, Davidson, Nate, Metselaar, Dennis S, Neel, Hans, Donson, Andrew, Griesinger, Andrea, Katagi, Hiroaki, Vijmasi, Trinka, Sola, Ismail, Alimova, Irina, Fosmire, Susan, Hulleman, Esther, Serkova, Natalie J, Hashizume, Rintaro, Hawkins, Cynthia, Carcaboso, Angel Montero, Gupta, Nalin, Jones, Ken, Foreman, Nicholas, Green, Adam, Vibhakar, Rajeev, Venkataraman, Sujatha
Publicado 2020

Senescence Induced by BMI1 Inhibition Is a Therapeutic Vulnerability in H3K27M-Mutant DIPG

por Balakrishnan, Ilango, Danis, Etienne, Pierce, Angela, Madhavan, Krishna, Wang, Dong, Dahl, Nathan, Sanford, Bridget, Birks, Diane K., Davidson, Nate, Metselaar, Dennis S., Meel, Michaël Hananja, Lemma, Rakeb, Donson, Andrew, Vijmasi, Trinka, Katagi, Hiroaki, Sola, Ismail, Fosmire, Susan, Alimova, Irina, Steiner, Jenna, Gilani, Ahmed, Hulleman, Esther, Serkova, Natalie J., Hashizume, Rintaro, Hawkins, Cynthia, Carcaboso, Angel M., Gupta, Nalin, Monje, Michelle, Jabado, Nada, Jones, Kenneth, Foreman, Nicholas, Green, Adam, Vibhakar, Rajeev, Venkataraman, Sujatha
Publicado 2020