Multiparametric Flow Cytometry-Based Immunophenotyping of Mouse Liver Immune Cells

por Vanekova, Lenka, Pimkova Polidarova, Marketa, Veverka, Vaclav, Birkus, Gabriel, Brazdova, Andrea
Publicado 2022

Molecular Determinants of GS-9620-Dependent TLR7 Activation

por Rebbapragada, Indrani, Birkus, Gabriel, Perry, Jason, Xing, Weimei, Kwon, HyockJoo, Pflanz, Stefan
Publicado 2016

Synthesis of phosphonate derivatives of 2′-deoxy-2′-fluorotetradialdose d-nucleosides and tetradialdose d-nucleosides

por Lášek, Tomáš, Dobiáš, Juraj, Buděšínský, Miloš, Kozák, Jaroslav, Lapuníková, Barbora, Rosenberg, Ivan, Birkuš, Gabriel, Páv, Ondřej
Publicado 2021

Ligand Strain and Its Conformational Complexity Is a Major Factor in the Binding of Cyclic Dinucleotides to STING Protein

por Smola, Miroslav, Gutten, Ondrej, Dejmek, Milan, Kožíšek, Milan, Evangelidis, Thomas, Tehrani, Zahra Aliakbar, Novotná, Barbora, Nencka, Radim, Birkuš, Gabriel, Rulíšek, Lubomír, Boura, Evzen
Publicado 2021

Contribution of the organic anion transporter OAT2 to the renal active tubular secretion of creatinine and mechanism for serum creatinine elevations caused by cobicistat

por Lepist, Eve-Irene, Zhang, Xuexiang, Hao, Jia, Huang, Jane, Kosaka, Alan, Birkus, Gabriel, Murray, Bernard P, Bannister, Roy, Cihlar, Tomas, Huang, Yong, Ray, Adrian S
Publicado 2014

Biochemical characterization of recombinant influenza A polymerase heterotrimer complex: Polymerase activity and mechanisms of action of nucleotide analogs

por Barauskas, Ona, Xing, Weimei, Aguayo, Esmeralda, Willkom, Madeleine, Sapre, Annapurna, Clarke, Michael, Birkus, Gabriel, Schultz, Brian E., Sakowicz, Roman, Kwon, HyockJoo, Feng, Joy Y.
Publicado 2017

Purine analogs as phosphatidylinositol 4-kinase IIIβ inhibitors

por Šála, Michal, Kögler, Martin, Plačková, Pavla, Mejdrová, Ivana, Hřebabecký, Hubert, Procházková, Eliška, Strunin, Dmytro, Lee, Gary, Birkus, Gabriel, Weber, Jan, Mertlíková-Kaiserová, Helena, Nencka, Radim
Publicado 2016

Biochemical characterization of recombinant influenza A polymerase heterotrimer complex: Endonuclease activity and evaluation of inhibitors

por Xing, Weimei, Barauskas, Ona, Kirschberg, Thorsten, Niedziela-Majka, Anita, Clarke, Michael, Birkus, Gabriel, Weissburg, Perry, Liu, Xiaohong, Schultz, Brian E., Sakowicz, Roman, Kwon, HyockJoo, Feng, Joy Y.
Publicado 2017

Nucleotide Prodrug Containing a Nonproteinogenic Amino Acid To Improve Oral Delivery of a Hepatitis C Virus Treatment

por Feng, Joy Y., Wang, Ting, Park, Yeojin, Babusis, Darius, Birkus, Gabriel, Xu, Yili, Voitenleitner, Christian, Fenaux, Martijn, Yang, Huiling, Eng, Stacey, Tirunagari, Neeraj, Kirschberg, Thorsten, Cho, Aesop, Ray, Adrian S.
Publicado 2018

Design, Synthesis, and Biochemical and Biological Evaluation of Novel 7-Deazapurine Cyclic Dinucleotide Analogues as STING Receptor Agonists

por Vavřina, Zdeněk, Perlíková, Pavla, Milisavljević, Nemanja, Chevrier, Florian, Smola, Miroslav, Smith, Joshua, Dejmek, Milan, Havlíček, Vojtěch, Buděšínský, Miloš, Liboska, Radek, Vaneková, Lenka, Brynda, Jiří, Boura, Evzen, Řezáčová, Pavlína, Hocek, Michal, Birkuš, Gabriel
Publicado 2022

Characterization of a KDM5 small molecule inhibitor with antiviral activity against hepatitis B virus

por Gilmore, Sarah A., Tam, Danny, Cheung, Tara L., Snyder, Chelsea, Farand, Julie, Dick, Ryan, Matles, Mike, Feng, Joy Y., Ramirez, Ricardo, Li, Li, Yu, Helen, Xu, Yili, Barnes, Dwight, Czerwieniec, Gregg, Brendza, Katherine M., Appleby, Todd C., Birkus, Gabriel, Willkom, Madeleine, Kobayashi, Tetsuya, Paoli, Eric, Labelle, Marc, Boesen, Thomas, Tay, Chin H., Delaney, William E., Notte, Gregory T., Schmitz, Uli, Feierbach, Becket
Publicado 2022