Catechol-O-Methyltransferase Genotype, Frailty, and Gait Speed: The Cardiovascular Health Study

por Mance, Shannon, Rosso, Andrea, Bis, Joshua, Studenski, Stephanie, Bohnen, Nico, Rosano, Caterina
Publicado 2020

Genome-Wide Association Analysis of Soluble ICAM-1 Concentration Reveals Novel Associations at the NFKBIK, PNPLA3, RELA, and SH2B3 Loci

por Paré, Guillaume, Ridker, Paul M., Rose, Lynda, Barbalic, Maja, Dupuis, Josée, Dehghan, Abbas, Bis, Joshua C., Benjamin, Emelia J., Shiffman, Dov, Parker, Alexander N., Chasman, Daniel I.
Publicado 2011

Sequence Analysis of Six Blood Pressure Candidate Regions in 4,178 Individuals: The Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Targeted Sequencing Study

por Morrison, Alanna C., Bis, Joshua C., Hwang, Shih-Jen, Ehret, Georg B., Lumley, Thomas, Rice, Kenneth, Muzny, Donna, Gibbs, Richard A., Boerwinkle, Eric, Psaty, Bruce M., Chakravarti, Aravinda, Levy, Daniel
Publicado 2014

Whole genome sequence analyses of brain imaging measures in the Framingham Study

por Sarnowski, Chloé, Satizabal, Claudia L., DeCarli, Charles, Pitsillides, Achilleas N., Cupples, L. Adrienne, Vasan, Ramachandran S., Wilson, James G., Bis, Joshua C., Fornage, Myriam, Beiser, Alexa S., DeStefano, Anita L., Dupuis, Josée, Seshadri, Sudha
Publicado 2018

Whole Genome Sequence-Based Analysis of a Model Complex Trait, High Density Lipoprotein Cholesterol

por Morrison, Alanna C., Voorman, Arend, Johnson, Andrew D., Liu, Xiaoming, Yu, Jin, Li, Alexander, Muzny, Donna, Yu, Fuli, Rice, Kenneth, Zhu, Chengsong, Bis, Joshua, Heiss, Gerardo, O’Donnell, Christopher J., Psaty, Bruce M., Cupples, L. Adrienne, Gibbs, Richard, Boerwinkle, Eric
Publicado 2013

Genomewide Association Study of Statin‐Induced Myopathy in Patients Recruited Using the UK Clinical Practice Research Datalink

por Carr, Daniel F., Francis, Ben, Jorgensen, Andrea L., Zhang, Eunice, Chinoy, Hector, Heckbert, Susan R., Bis, Joshua C., Brody, Jennifer A., Floyd, James S., Psaty, Bruce M., Molokhia, Mariam, Lapeyre‐Mestre, Maryse, Conforti, Anita, Alfirevic, Ana, van Staa, Tjeerd, Pirmohamed, Munir
Publicado 2019

Variant-specific inflation factors for assessing population stratification at the phenotypic variance level

por Sofer, Tamar, Zheng, Xiuwen, Laurie, Cecelia A., Gogarten, Stephanie M., Brody, Jennifer A., Conomos, Matthew P., Bis, Joshua C., Thornton, Timothy A., Szpiro, Adam, O’Connell, Jeffrey R., Lange, Ethan M., Gao, Yan, Cupples, L. Adrienne, Psaty, Bruce M., Rice, Kenneth M.
Publicado 2021

Large‐scale sequencing studies expand the known genetic architecture of Alzheimer's disease

por Xue, Diane, Bush, William S., Renton, Alan E., Marcora, Edoardo A., Bis, Joshua C., Kunkle, Brian W., Boerwinkle, Eric, DeStefano, Anita L., Farrer, Lindsay, Goate, Alison, Mayeux, Richard, Pericak‐Vance, Margaret, Schellenberg, Gerard, Seshadri, Sudha, Wijsman, Ellen, Haines, Jonathan L., Blue, Elizabeth E.
Publicado 2021

The impact of APOE genotype on survival: Results of 38,537 participants from six population-based cohorts (E2-CHARGE)

por Wolters, Frank J., Yang, Qiong, Biggs, Mary L., Jakobsdottir, Johanna, Li, Shuo, Evans, Daniel S., Bis, Joshua C., Harris, Tamara B., Vasan, Ramachandran S., Zilhao, Nuno R., Ghanbari, Mohsen, Ikram, M. Arfan, Launer, Lenore, Psaty, Bruce M., Tranah, Gregory J., Kulminski, Alexander M., Gudnason, Vilmundur, Seshadri, Sudha
Publicado 2019

Biomedical consequences of elevated cholesterol-containing lipoproteins and apolipoproteins on cardiovascular and non-cardiovascular outcomes

por Schmidt, Amand F., Joshi, Roshni, Gordillo-Marañón, Maria, Drenos, Fotios, Charoen, Pimphen, Giambartolomei, Claudia, Bis, Joshua C., Gaunt, Tom R., Hughes, Alun D., Lawlor, Deborah A., Wong, Andrew, Price, Jackie F., Chaturvedi, Nishi, Wannamethee, Goya, Franceschini, Nora, Kivimaki, Mika, Hingorani, Aroon D., Finan, Chris
Publicado 2023

Key variants via Alzheimer’s Disease Sequencing Project whole genome sequence data

por Wang, Yanbing, Sarnowski, Chloé, Lin, Honghuang, Pitsillides, Achilleas N, Heard-Costa, Nancy L, Choi, Seung Hoan, Wang, Dongyu, Bis, Joshua C, Blue, Elizabeth E, Boerwinkle, Eric, De Jager, Philip L, Fornage, Myriam, Wijsman, Ellen M, Seshadri, Sudha, Dupuis, Josée, Peloso, Gina M, DeStefano, Anita L
Publicado 2023

Common folate gene variant, MTHFR C677T, is associated with brain structure in two independent cohorts of people with mild cognitive impairment()

por Rajagopalan, Priya, Jahanshad, Neda, Stein, Jason L., Hua, Xue, Madsen, Sarah K., Kohannim, Omid, Hibar, Derrek P., Toga, Arthur W., Jack, Clifford R., Saykin, Andrew J., Green, Robert C., Weiner, Michael W., Bis, Joshua C., Kuller, Lewis H., Riverol, Mario, Becker, James T., Lopez, Oscar L., Thompson, Paul M.
Publicado 2012

Population Genomic Analysis of 962 Whole Genome Sequences of Humans Reveals Natural Selection in Non-Coding Regions

por Yu, Fuli, Lu, Jian, Liu, Xiaoming, Gazave, Elodie, Chang, Diana, Raj, Srilakshmi, Hunter-Zinck, Haley, Blekhman, Ran, Arbiza, Leonardo, Van Hout, Cris, Morrison, Alanna, Johnson, Andrew D., Bis, Joshua, Cupples, L. Adrienne, Psaty, Bruce M., Muzny, Donna, Yu, Jin, Gibbs, Richard A., Keinan, Alon, Clark, Andrew G., Boerwinkle, Eric
Publicado 2015

Lp-PLA(2), scavenger receptor class B type I gene (SCARB1) rs10846744 variant, and cardiovascular disease

por Manichaikul, Ani, Wang, Xin-Qun, Li, Li, Erdmann, Jeanette, Lettre, Guillaume, Bis, Joshua C., Waterworth, Dawn, Cushman, Mary, Jenny, Nancy S., Post, Wendy S., Palmas, Walter, Tsai, Michael Y., Wallentin, Lars, White, Harvey, Schunkert, Heribert, O’Donnell, Christopher J., Herrington, David M., Rich, Stephen S., O’Donoghue, Michelle L., Rodriguez, Annabelle
Publicado 2018

Admixture mapping implicates 13q33.3 as ancestry-of-origin locus for Alzheimer disease in Hispanic and Latino populations

por Horimoto, Andrea R.V.R., Boyken, Lisa A., Blue, Elizabeth E., Grinde, Kelsey E., Nafikov, Rafael A., Sohi, Harkirat K., Nato, Alejandro Q., Bis, Joshua C., Brusco, Luis I., Morelli, Laura, Ramirez, Alfredo, Dalmasso, Maria Carolina, Temple, Seth, Satizabal, Claudia, Browning, Sharon R., Seshadri, Sudha, Wijsman, Ellen M., Thornton, Timothy A.
Publicado 2023

Association of Peripheral Lymphocyte Subsets with Cognitive Decline and Dementia: The Cardiovascular Health Study

por Fohner, Alison E., Sitlani, Colleen M., Buzkova, Petra, Doyle, Margaret F., Liu, Xiaojuan, Bis, Joshua C., Fitzpatrick, Annette, Heckbert, Susan R., Huber, Sally A., Kuller, Lewis, Longstreth, William T., Feinstein, Matthew J., Freiberg, Matthew, Olson, Nels C., Seshadri, Sudha, Lopez, Oscar, Odden, Michelle C., Tracy, Russell P., Psaty, Bruce M., Delaney, Joseph A., Floyd, James S.
Publicado 2022

Druggable proteins influencing cardiac structure and function: Implications for heart failure therapies and cancer cardiotoxicity

por Schmidt, Amand F., Bourfiss, Mimount, Alasiri, Abdulrahman, Puyol-Anton, Esther, Chopade, Sandesh, van Vugt, Marion, van der Laan, Sander W., Gross, Christian, Clarkson, Chris, Henry, Albert, Lumbers, Tom R., van der Harst, Pim, Franceschini, Nora, Bis, Joshua C., Velthuis, Birgitta K., te Riele, Anneline S. J. M., Hingorani, Aroon D., Ruijsink, Bram, Asselbergs, Folkert W., van Setten, Jessica, Finan, Chris
Publicado 2023

Cholesteryl ester transfer protein (CETP) as a drug target for cardiovascular disease

por Schmidt, Amand F., Hunt, Nicholas B., Gordillo-Marañón, Maria, Charoen, Pimphen, Drenos, Fotios, Kivimaki, Mika, Lawlor, Deborah A., Giambartolomei, Claudia, Papacosta, Olia, Chaturvedi, Nishi, Bis, Joshua C., O’Donnell, Christopher J., Wannamethee, Goya, Wong, Andrew, Price, Jackie F., Hughes, Alun D., Gaunt, Tom R., Franceschini, Nora, Mook-Kanamori, Dennis O., Zwierzyna, Magdalena, Sofat, Reecha, Hingorani, Aroon D., Finan, Chris
Publicado 2021

Genes From a Translational Analysis Support a Multifactorial Nature of White Matter Hyperintensities

por Lopez, Lorna M., Hill, W. David, Harris, Sarah E., Valdes Hernandez, Maria, Munoz Maniega, Susana, Bastin, Mark E., Bailey, Emma, Smith, Colin, McBride, Martin, McClure, John, Graham, Delyth, Dominiczak, Anna, Yang, Qiong, Fornage, Myriam, Ikram, M. Arfan, Debette, Stephanie, Launer, Lenore, Bis, Joshua C., Schmidt, Reinhold, Seshadri, Sudha, Porteous, David J., Starr, John, Deary, Ian J., Wardlaw, Joanna M.
Publicado 2015

Genetic Evidence for a Normal-Weight “Metabolically Obese” Phenotype Linking Insulin Resistance, Hypertension, Coronary Artery Disease, and Type 2 Diabetes

por Yaghootkar, Hanieh, Scott, Robert A., White, Charles C., Zhang, Weihua, Speliotes, Elizabeth, Munroe, Patricia B., Ehret, Georg B., Bis, Joshua C., Fox, Caroline S., Walker, Mark, Borecki, Ingrid B., Knowles, Joshua W., Yerges-Armstrong, Laura, Ohlsson, Claes, Perry, John R.B., Chambers, John C., Kooner, Jaspal S., Franceschini, Nora, Langenberg, Claudia, Hivert, Marie-France, Dastani, Zari, Richards, J. Brent, Semple, Robert K., Frayling, Timothy M.
Publicado 2014