Role of Factor H and Related Proteins in Regulating Complement Activation in the Macula, and Relevance to Age-Related Macular Degeneration

por Clark, Simon J., Bishop, Paul N.
Publicado 2014

The eye as a complement dysregulation hotspot

por Clark, Simon J., Bishop, Paul N.
Publicado 2017

The Proteoglycan Glycomatrix: A Sugar Microenvironment Essential for Complement Regulation

por Clark, Simon J., Bishop, Paul N., Day, Anthony J.
Publicado 2013

Analysis of opticin binding to collagen fibrils identifies a single binding site in the gap region and a high specificity towards thin heterotypic fibrils containing collagens II,...

por Hansen, Uwe, Holmes, David F., Bruckner, Peter, Bishop, Paul N.
Publicado 2020

Enrichment of Bruch's Membrane from Human Donor Eyes

por McHarg, Selina, Brace, Nicole, Bishop, Paul N., Clark, Simon J.
Publicado 2015

Complementing the Sugar Code: Role of GAGs and Sialic Acid in Complement Regulation

por Langford-Smith, Alex, Day, Anthony J., Bishop, Paul N., Clark, Simon J.
Publicado 2015

Bruch’s Membrane Compartmentalizes Complement Regulation in the Eye with Implications for Therapeutic Design in Age-Related Macular Degeneration

por Clark, Simon J., McHarg, Selina, Tilakaratna, Viranga, Brace, Nicole, Bishop, Paul N.
Publicado 2017

Efficacy and Safety of Glycosidic Enzymes for Improved Gene Delivery to the Retina following Intravitreal Injection in Mice

por Cehajic-Kapetanovic, Jasmina, Milosavljevic, Nina, Bedford, Robert A., Lucas, Robert J., Bishop, Paul N.
Publicado 2017

Viral Transduction of Human Rod Opsin or Channelrhodopsin Variants to Mouse ON Bipolar Cells Does Not Impact Retinal Anatomy or Cause Measurable Death in the Targeted Cells

por Wright, Phillip, Rodgers, Jessica, Wynne, Jonathan, Bishop, Paul N., Lucas, Robert J., Milosavljevic, Nina
Publicado 2021

Glycosidic enzymes enhance retinal transduction following intravitreal delivery of AAV2

por Cehajic-Kapetanovic, Jasmina, Le Goff, Magali M., Allen, Annette, Lucas, Robert J., Bishop, Paul N.
Publicado 2011

Metabolomic analysis of rat serum in streptozotocin-induced diabetes and after treatment with oral triethylenetetramine (TETA)

por Ugarte, Marta, Brown, Marie, Hollywood, Katherine A, Cooper, Garth J, Bishop, Paul N, Dunn, Warwick B
Publicado 2012

LRRCE: a leucine-rich repeat cysteine capping motif unique to the chordate lineage

por Park, Hosil, Huxley-Jones, Julie, Boot-Handford, Ray P, Bishop, Paul N, Attwood, Teresa K, Bella, Jordi
Publicado 2008

Opticin Exerts Its Anti-angiogenic Activity by Regulating Extracellular Matrix Adhesiveness

por Le Goff, Magali M., Sutton, Matthew J., Slevin, Mark, Latif, Ayse, Humphries, Martin J., Bishop, Paul N.
Publicado 2012

Age and Smoking Related Changes in Metal Ion Levels in Human Lens: Implications for Cataract Formation

por Langford-Smith, Alex, Tilakaratna, Viranga, Lythgoe, Paul R., Clark, Simon J., Bishop, Paul N., Day, Anthony J.
Publicado 2016

Spatial distribution of metabolites in the retina and its relevance to studies of metabolic retinal disorders

por Bonelli, Roberto, Woods, Sasha M., Lockwood, Sarah, Bishop, Paul N., Khan, Kamron N., Bahlo, Melanie, Ansell, Brendan R. E., Fruttiger, Marcus
Publicado 2023

Deficient copper concentrations in dried-defatted hepatic tissue from ob/ob mice: A potential model for study of defective copper regulation in metabolic liver disease

por Church, Stephanie J., Begley, Paul, Kureishy, Nina, McHarg, Selina, Bishop, Paul N., Bechtold, David A., Unwin, Richard D., Cooper, Garth J.S.
Publicado 2015

In vivo effect of opticin deficiency in cartilage in a surgically induced mouse model of osteoarthritis

por Farrán, Aina, Valverde-Franco, Gladys, Tío, Laura, Lussier, Bertrand, Fahmi, Hassan, Pelletier, Jean-Pierre, Bishop, Paul N., Monfort, Jordi, Martel-Pelletier, Johanne
Publicado 2018

Restoration of Vision with Ectopic Expression of Human Rod Opsin

por Cehajic-Kapetanovic, Jasmina, Eleftheriou, Cyril, Allen, Annette E., Milosavljevic, Nina, Pienaar, Abigail, Bedford, Robert, Davis, Katherine E., Bishop, Paul N., Lucas, Robert J.
Publicado 2015

Opticin, a small leucine-rich proteoglycan, is uniquely expressed and translocated to the nucleus of chronic lymphocytic leukemia cells

por Mikaelsson, Eva, Österborg, Anders, Tahmasebi Fard, Zahra, Mahmoudi, Ahmad, Mahmoudian, Jafar, Jeddi-Tehrani, Mahmood, Akhondi, Mehdi, Shokri, Fazel, Bishop, Paul N, Rabbani, Hodjattallah, Mellstedt, Håkan
Publicado 2013

Beyond factor H: The impact of genetic-risk variants for age-related macular degeneration on circulating factor-H-like 1 and factor-H-related protein concentrations

por Cipriani, Valentina, Tierney, Anna, Griffiths, John R., Zuber, Verena, Sergouniotis, Panagiotis I., Yates, John R.W., Moore, Anthony T., Bishop, Paul N., Clark, Simon J., Unwin, Richard D.
Publicado 2021