Physiologically Based Pharmacokinetic Modeling of Extracellular Vesicles

por Kumar, Prashant, Mehta, Darshan, Bissler, John J.
Publicado 2023

Glomerulocystic kidney disease

por Bissler, John J., Siroky, Brian J., Yin, Hong
Publicado 2010

Replication dependent instability at (CTG)•(CAG) repeat hairpins in human cells

por Liu, Guoqi, Chen, Xiaomi, Bissler, John J., Sinden, Richard R., Leffak, Michael
Publicado 2010

Cell Cycle Control and DNA Damage Response of Conditionally Immortalized Urothelial Cells

por Dixon, Bradley P., Henry, Jeff, Siroky, Brian J., Chu, Albert, Groen, Pamela A., Bissler, John J.
Publicado 2011

Tsc Gene Locus Disruption and Differences in Renal Epithelial Extracellular Vesicles

por Kumar, Prashant, Zadjali, Fahad, Yao, Ying, Siroky, Brian, Astrinidis, Aristotelis, Gross, Kenneth W., Bissler, John J.
Publicado 2021

Pooled analysis of menstrual irregularities from three major clinical studies evaluating everolimus for the treatment of tuberous sclerosis complex

por Sparagana, Steven, Franz, David N., Krueger, Darcy A., Bissler, John J., Berkowitz, Noah, Burock, Karin, Kingswood, J. Christopher
Publicado 2017

Tuberous Sclerosis Complex Axis Controls Renal Extracellular Vesicle Production and Protein Content

por Zadjali, Fahad, Kumar, Prashant, Yao, Ying, Johnson, Daniel, Astrinidis, Aristotelis, Vogel, Peter, Gross, Kenneth W., Bissler, John J.
Publicado 2020

Single Gene Mutations in Pkd1 or Tsc2 Alter Extracellular Vesicle Production and Trafficking

por Kumar, Prashant, Zadjali, Fahad, Yao, Ying, Köttgen, Michael, Hofherr, Alexis, Gross, Kenneth W., Mehta, Darshan, Bissler, John J.
Publicado 2022

Tsc2 mutation induces renal tubular cell nonautonomous disease

por Kumar, Prashant, Zadjali, Fahad, Yao, Ying, Johnson, Daniel, Siroky, Brian, Astrinidis, Aristotelis, Vogel, Peter, Gross, Kenneth W., Bissler, John J.
Publicado 2021

Insight into response to mTOR inhibition when PKD1 and TSC2 are mutated

por Cabrera-López, Cristina, Bullich, Gemma, Martí, Teresa, Català, Violeta, Ballarín, Jose, Bissler, John J., Harris, Peter C., Ars, Elisabet, Torra, Roser
Publicado 2015

Kidney intercalated cells and the transcription factor FOXi1 drive cystogenesis in tuberous sclerosis complex

por Barone, Sharon, Zahedi, Kamyar, Brooks, Marybeth, Henske, Elizabeth P., Yang, Yirong, Zhang, Erik, Bissler, John J., Yu, Jane J., Soleimani, Manoocher
Publicado 2021

The effect of everolimus on renal angiomyolipoma in pediatric patients with tuberous sclerosis being treated for subependymal giant cell astrocytoma

por Bissler, John J., Franz, David N., Frost, Michael D., Belousova, Elena, Bebin, E. Martina, Sparagana, Steven, Berkowitz, Noah, Ridolfi, Antonia, Kingswood, J. Christopher
Publicado 2017

Rapalog resistance is associated with mesenchymal-type changes in Tsc2-null cells

por Valianou, Matthildi, Filippidou, Natalia, Johnson, Daniel L., Vogel, Peter, Zhang, Erik Y., Liu, Xiaolei, Lu, Yiyang, Yu, Jane J., Bissler, John J., Astrinidis, Aristotelis
Publicado 2019

Effect of everolimus on renal function in patients with tuberous sclerosis complex: evidence from EXIST-1 and EXIST-2

por Bissler, John J, Budde, Klemens, Sauter, Matthias, Franz, David N, Zonnenberg, Bernard A, Frost, Michael D, Belousova, Elena, Berkowitz, Noah, Ridolfi, Antonia, Christopher Kingswood, J
Publicado 2019

Angiomyolipoma rebound tumor growth after discontinuation of everolimus in patients with tuberous sclerosis complex or sporadic lymphangioleiomyomatosis

por Bissler, John J., Nonomura, Norio, Budde, Klemens, Zonnenberg, Bernard A., Fischereder, Michael, Voi, Maurizio, Louveau, Anne-Laure, Herbst, Fabian, Bebin, E. Martina, Curatolo, Paolo, Zonta, Andrea, Belousova, Elena
Publicado 2018

A step-wise approach for establishing a multidisciplinary team for the management of tuberous sclerosis complex: a Delphi consensus report

por Auvin, Stéphane, Bissler, John J., Cottin, Vincent, Fujimoto, Ayataka, Hofbauer, Günther F. L., Jansen, Anna C., Jóźwiak, Sergiusz, Kerecuk, Larissa, Kingswood, J. Christopher, Moavero, Romina, Torra, Roser, Villanueva, Vicente
Publicado 2019

Everolimus long-term use in patients with tuberous sclerosis complex: Four-year update of the EXIST-2 study

por Bissler, John J., Kingswood, J. Chris, Radzikowska, Elzbieta, Zonnenberg, Bernard A., Belousova, Elena, Frost, Michael D., Sauter, Matthias, Brakemeier, Susanne, de Vries, Petrus J., Berkowitz, Noah, Voi, Maurizio, Peyrard, Severine, Budde, Klemens
Publicado 2017

Tuberous sclerosis complex exhibits a new renal cystogenic mechanism

por Bissler, John J., Zadjali, Fahad, Bridges, Dave, Astrinidis, Aristotelis, Barone, Sharon, Yao, Ying, Redd, JeAnna R., Siroky, Brian J., Wang, Yanqing, Finley, Joel T., Rusiniak, Michael E., Baumann, Heinz, Zahedi, Kamyar, Gross, Kenneth W., Soleimani, Manoocher
Publicado 2019

The human DEK oncogene regulates DNA damage response signaling and repair

por Kavanaugh, Gina M., Wise-Draper, Trisha M., Morreale, Richard J., Morrison, Monique A., Gole, Boris, Schwemberger, Sandy, Tichy, Elisia D., Lu, Lu, Babcock, George F., Wells, James M., Drissi, Rachid, Bissler, John J., Stambrook, Peter J., Andreassen, Paul R., Wiesmüller, Lisa, Wells, Susanne I.
Publicado 2011