Phosphite binding by the HtxB periplasmic binding protein depends on the protonation state of the ligand

por Adams, Nathan B. P., Robertson, Angus J., Hunter, C. Neil, Hitchcock, Andrew, Bisson, Claudine
Publicado 2019

Peptidic boronic acids are potent cell-permeable inhibitors of the malaria parasite egress serine protease SUB1

por Lidumniece, Elina, Withers-Martinez, Chrislaine, Hackett, Fiona, Collins, Christine R., Perrin, Abigail J., Koussis, Konstantinos, Bisson, Claudine, Blackman, Michael J., Jirgensons, Aigars
Publicado 2021

The molecular basis of phosphite and hypophosphite recognition by ABC-transporters

por Bisson, Claudine, Adams, Nathan B. P., Stevenson, Ben, Brindley, Amanda A., Polyviou, Despo, Bibby, Thomas S., Baker, Patrick J., Hunter, C. Neil, Hitchcock, Andrew
Publicado 2017

Elucidating the structural basis for differing enzyme inhibitor potency by cryo-EM

por Rawson, Shaun, Bisson, Claudine, Hurdiss, Daniel L., Fazal, Asif, McPhillie, Martin J., Sedelnikova, Svetlana E., Baker, Patrick J., Rice, David W., Muench, Stephen P.
Publicado 2018

Crystal Structures Reveal that the Reaction Mechanism of Imidazoleglycerol-Phosphate Dehydratase Is Controlled by Switching Mn(II) Coordination

por Bisson, Claudine, Britton, K. Linda, Sedelnikova, Svetlana E., Rodgers, H. Fiona, Eadsforth, Thomas C., Viner, Russell C., Hawkes, Tim R., Baker, Patrick J., Rice, David W.
Publicado 2015

Mirror‐Image Packing Provides a Molecular Basis for the Nanomolar Equipotency of Enantiomers of an Experimental Herbicide

por Bisson, Claudine, Britton, K. Linda, Sedelnikova, Svetlana E., Rodgers, H. Fiona, Eadsforth, Thomas C., Viner, Russell C., Hawkes, Tim R., Baker, Patrick J., Rice, David W.
Publicado 2016

Structural and functional studies of histidine biosynthesis in Acanthamoeba spp. demonstrates a novel molecular arrangement and target for antimicrobials

por Rice, Christopher A., Campbell, Sara J., Bisson, Claudine, Owen, Hayley J., Sedelnikova, Svetlana E., Baker, Patrick J., Rice, David W., Henriquez, Fiona L., Roberts, Craig W.
Publicado 2018

(Identification and structural analysis of the tripartite α-pore forming toxin of Aeromonas hydrophila)

por Wilson, Jason S., Churchill-Angus, Alicia M., Davies, Simon P., Sedelnikova, Svetlana E., Tzokov, Svetomir B., Rafferty, John B., Bullough, Per A., Bisson, Claudine, Baker, Patrick J.
Publicado 2019

An Exported Kinase Family Mediates Species-Specific Erythrocyte Remodelling and Virulence in Human Malaria

por Davies, Heledd, Belda, Hugo, Broncel, Malgorzata, Ye, Xingda, Bisson, Claudine, Introini, Viola, Dorin-Semblat, Dominique, Semblat, Jean-Philippe, Tibúrcio, Marta, Gamain, Benoit, Kaforou, Myrsini, Treeck, Moritz
Publicado 2020

An Enzyme with High Catalytic Proficiency Utilizes Distal Site Substrate Binding Energy to Stabilize the Closed State but at the Expense of Substrate Inhibition

por Robertson, Angus J., Cruz-Navarrete, F. Aaron, Wood, Henry P., Vekaria, Nikita, Hounslow, Andrea M., Bisson, Claudine, Cliff, Matthew J., Baxter, Nicola J., Waltho, Jonathan P.
Publicado 2022

The mechanism of a formaldehyde-sensing transcriptional regulator

por Denby, Katie J., Iwig, Jeffrey, Bisson, Claudine, Westwood, Jodie, Rolfe, Matthew D., Sedelnikova, Svetlana E., Higgins, Khadine, Maroney, Michael J., Baker, Patrick J., Chivers, Peter T., Green, Jeffrey
Publicado 2016

Malaria Parasite Schizont Egress Antigen-1 Plays an Essential Role in Nuclear Segregation during Schizogony

por Perrin, Abigail J., Bisson, Claudine, Faull, Peter A., Renshaw, Matthew J., Lees, Rebecca A., Fleck, Roland A., Saibil, Helen R., Snijders, Ambrosius P., Baker, David A., Blackman, Michael J.
Publicado 2021

Cyclic AMP signalling controls key components of malaria parasite host cell invasion machinery

por Patel, Avnish, Perrin, Abigail J., Flynn, Helen R., Bisson, Claudine, Withers-Martinez, Chrislaine, Treeck, Moritz, Flueck, Christian, Nicastro, Giuseppe, Martin, Stephen R., Ramos, Andres, Gilberger, Tim W., Snijders, Ambrosius P., Blackman, Michael J., Baker, David A.
Publicado 2019

High-resolution crystal structure of human asparagine synthetase enables analysis of inhibitor binding and selectivity

por Zhu, Wen, Radadiya, Ashish, Bisson, Claudine, Wenzel, Sabine, Nordin, Brian E., Martínez-Márquez, Francisco, Imasaki, Tsuyoshi, Sedelnikova, Svetlana E., Coricello, Adriana, Baumann, Patrick, Berry, Alexandria H., Nomanbhoy, Tyzoon K., Kozarich, John W., Jin, Yi, Rice, David W., Takagi, Yuichiro, Richards, Nigel G. J.
Publicado 2019

Author Correction: High-resolution crystal structure of human asparagine synthetase enables analysis of inhibitor binding and selectivity

por Zhu, Wen, Radadiya, Ashish, Bisson, Claudine, Wenzel, Sabine, Nordin, Brian E., Martínez-Márquez, Francisco, Imasaki, Tsuyoshi, Sedelnikova, Svetlana E., Coricello, Adriana, Baumann, Patrick, Berry, Alexandria H., Nomanbhoy, Tyzoon K., Kozarich, John W., Jin, Yi, Rice, David W., Takagi, Yuichiro, Richards, Nigel G. J.
Publicado 2019