GDNF Therapy: Can We Make It Work?

por Björklund, Anders
Publicado 2021

Replacing Dopamine Neurons in Parkinson’s Disease: How did it happen?

por Björklund, Anders, Lindvall, Olle
Publicado 2017

Neuronal Replacement as a Tool for Basal Ganglia Circuitry Repair: 40 Years in Perspective

por Björklund, Anders, Parmar, Malin
Publicado 2020

Dopamine Cell Therapy: From Cell Replacement to Circuitry Repair

por Björklund, Anders, Parmar, Malin
Publicado 2021

The Amphetamine Induced Rotation Test: A Re-Assessment of Its Use as a Tool to Monitor Motor Impairment and Functional Recovery in Rodent Models of Parkinson’s Disease

por Björklund, Anders, Dunnett, Stephen B.
Publicado 2019

A Combined α-Synuclein/Fibril (SynFib) Model of Parkinson-Like Synucleinopathy Targeting the Nigrostriatal Dopamine System

por Björklund, Anders, Nilsson, Fredrik, Mattsson, Bengt, Hoban, Deirdre B., Parmar, Malin
Publicado 2022

Gli1 Is an Inducing Factor in Generating Floor Plate Progenitor Cells from Human Embryonic Stem Cells

por Denham, Mark, Thompson, Lachlan H, Leung, Jessie, Pébay, Alice, Björklund, Anders, Dottori, Mirella
Publicado 2010

α-Synuclein induced toxicity in brain stem serotonin neurons mediated by an AAV vector driven by the tryptophan hydroxylase promoter

por Wan, Oi Wan, Shin, Eunju, Mattsson, Bengt, Caudal, Dorian, Svenningsson, Per, Björklund, Anders
Publicado 2016

Are Stem Cell-Based Therapies for Parkinson’s Disease Ready for the Clinic in 2016?

por Barker, Roger A., Parmar, Malin, Kirkeby, Agnete, Björklund, Anders, Thompson, Lachlan, Brundin, Patrik
Publicado 2016

The A9 dopamine neuron component in grafts of ventral mesencephalon is an important determinant for recovery of motor function in a rat model of Parkinson’s disease

por Grealish, Shane, Jönsson, Marie E., Li, Meng, Kirik, Deniz, Björklund, Anders, Thompson, Lachlan H.
Publicado 2010

Alpha-Synuclein Cell-to-Cell Transfer and Seeding in Grafted Dopaminergic Neurons In Vivo

por Angot, Elodie, Steiner, Jennifer A., Lema Tomé, Carla M., Ekström, Peter, Mattsson, Bengt, Björklund, Anders, Brundin, Patrik
Publicado 2012

Monosynaptic Tracing using Modified Rabies Virus Reveals Early and Extensive Circuit Integration of Human Embryonic Stem Cell-Derived Neurons

por Grealish, Shane, Heuer, Andreas, Cardoso, Tiago, Kirkeby, Agnete, Jönsson, Marie, Johansson, Jenny, Björklund, Anders, Jakobsson, Johan, Parmar, Malin
Publicado 2015

Eltoprazine counteracts l-DOPA-induced dyskinesias in Parkinson’s disease: a dose-finding study

por Svenningsson, Per, Rosenblad, Carl, af Edholm Arvidsson, Karolina, Wictorin, Klas, Keywood, Charlotte, Shankar, Bavani, Lowe, David A., Björklund, Anders, Widner, Håkan
Publicado 2015

Grafts Derived from an α-Synuclein Triplication Patient Mediate Functional Recovery but Develop Disease-Associated Pathology in the 6-OHDA Model of Parkinson’s Disease

por Shrigley, Shelby, Nilsson, Fredrik, Mattsson, Bengt, Fiorenzano, Alessandro, Mudannayake, Janitha, Bruzelius, Andreas, Ottosson, Daniella Rylander, Björklund, Anders, Hoban, Deirdre B., Parmar, Malin
Publicado 2021

Target‐specific forebrain projections and appropriate synaptic inputs of hESC‐derived dopamine neurons grafted to the midbrain of parkinsonian rats

por Cardoso, Tiago, Adler, Andrew F., Mattsson, Bengt, Hoban, Deirdre B., Nolbrant, Sara, Wahlestedt, Jenny Nelander, Kirkeby, Agnete, Grealish, Shane, Björklund, Anders, Parmar, Malin
Publicado 2018

hESC-Derived Dopaminergic Transplants Integrate into Basal Ganglia Circuitry in a Preclinical Model of Parkinson’s Disease

por Adler, Andrew F., Cardoso, Tiago, Nolbrant, Sara, Mattsson, Bengt, Hoban, Deirdre B., Jarl, Ulla, Wahlestedt, Jenny Nelander, Grealish, Shane, Björklund, Anders, Parmar, Malin
Publicado 2019

Impact of α-synuclein pathology on transplanted hESC-derived dopaminergic neurons in a humanized α-synuclein rat model of PD

por Hoban, Deirdre B., Shrigley, Shelby, Mattsson, Bengt, Breger, Ludivine S., Jarl, Ulla, Cardoso, Tiago, Nelander Wahlestedt, Jenny, Luk, Kelvin C., Björklund, Anders, Parmar, Malin
Publicado 2020

Human ESC-Derived Dopamine Neurons Show Similar Preclinical Efficacy and Potency to Fetal Neurons when Grafted in a Rat Model of Parkinson’s Disease

por Grealish, Shane, Diguet, Elsa, Kirkeby, Agnete, Mattsson, Bengt, Heuer, Andreas, Bramoulle, Yann, Van Camp, Nadja, Perrier, Anselme L., Hantraye, Philippe, Björklund, Anders, Parmar, Malin
Publicado 2014

Vector-mediated l-3,4-dihydroxyphenylalanine delivery reverses motor impairments in a primate model of Parkinson’s disease

por Rosenblad, Carl, Li, Qin, Pioli, Elsa Y., Dovero, Sandra, Antunes, André SLM, Agúndez, Leticia, Bardelli, Martino, Linden, R. Michael, Henckaerts, Els, Björklund, Anders, Bezard, Erwan, Björklund, Tomas
Publicado 2019

Cyclosporin promotes neurorestoration and cell replacement therapy in pre-clinical models of Parkinson’s disease

por Tamburrino, Anna, Churchill, Madeline J., Wan, Oi W., Colino-Sanguino, Yolanda, Ippolito, Rossana, Bergstrand, Sofie, Wolf, Daniel A., Herz, Niculin J., Sconce, Michelle D., Björklund, Anders, Meshul, Charles K., Decressac, Mickael
Publicado 2015