Key role of a structural water molecule for the specificity of 14F7—An antitumor antibody targeting the NeuGc GM3 ganglioside

por Bjerregaard-Andersen, Kaare, Abraha, Fana, Johannesen, Hedda, Oscarson, Stefan, Moreno, Ernesto, Krengel, Ute
Publicado 2021

α-synuclein buildup is alleviated via ESCRT-dependent endosomal degradation brought about by p38MAPK inhibition in cells expressing p25α

por Borland, Helena, Rasmussen, Izabela, Bjerregaard-Andersen, Kaare, Rasmussen, Michel, Olsen, Anders, Vilhardt, Frederik
Publicado 2022

The N-terminal cytoplasmic region of NCBE displays features of an intrinsic disordered structure and represents a novel target for specific drug screening

por Bjerregaard-Andersen, Kaare, Perdreau-Dahl, Harmonie, Guldsten, Hanne, Praetorius, Jeppe, Jensen, Jan K., Morth, Jens P.
Publicado 2013

The crystal structure of the regulatory domain of the human sodium-driven chloride/bicarbonate exchanger

por Alvadia, Carolina M., Sommer, Theis, Bjerregaard-Andersen, Kaare, Damkier, Helle Hasager, Montrasio, Michele, Aalkjaer, Christian, Morth, J. Preben
Publicado 2017

A fundamental catalytic difference between zinc and manganese dependent enzymes revealed in a bacterial isatin hydrolase

por Sommer, Theis, Bjerregaard-Andersen, Kaare, Uribe, Lalita, Etzerodt, Michael, Diezemann, Gregor, Gauss, Jürgen, Cascella, Michele, Morth, J. Preben
Publicado 2018

Perdeuterated GbpA Enables Neutron Scattering Experiments of a Lytic Polysaccharide Monooxygenase

por Sørensen, H. V., Montserrat-Canals, Mateu, Loose, Jennifer S. M., Fisher, S. Zoë, Moulin, Martine, Blakeley, Matthew P., Cordara, Gabriele, Bjerregaard-Andersen, Kaare, Krengel, Ute
Publicado 2023

Soluble T-cell receptor design influences functional yield in an E. coli chaperone-assisted expression system

por Gunnarsen, Kristin Støen, Høydahl, Lene Støkken, Neumann, Ralf Stefan, Bjerregaard-Andersen, Kaare, Nilssen, Nicolay Rustad, Sollid, Ludvig Magne, Sandlie, Inger, Løset, Geir Åge
Publicado 2018

The Structural Combination of SIL and MODAG Scaffolds Fails to Enhance Binding to α-Synuclein but Reveals Promising Affinity to Amyloid β

por Di Nanni, Adriana, Saw, Ran Sing, Bowden, Gregory D., Bidesi, Natasha S. R., Bjerregaard-Andersen, Kaare, Korat, Špela, Herth, Matthias M., Pichler, Bernd J., Herfert, Kristina, Maurer, Andreas
Publicado 2023

A Fluorescent Probe as a Lead Compound for a Selective α-Synuclein PET Tracer: Development of a Library of 2-Styrylbenzothiazoles and Biological Evaluation of [(18)F]PFSB and [(18)...

por Di Nanni, Adriana, Saw, Ran Sing, Battisti, Umberto M., Bowden, Gregory D., Boeckermann, Adam, Bjerregaard-Andersen, Kaare, Pichler, Bernd J., Herfert, Kristina, Herth, Matthias M., Maurer, Andreas
Publicado 2023

Crystal structure of an L chain optimised 14F7 anti-ganglioside Fv suggests a unique tumour-specificity through an unusual H-chain CDR3 architecture

por Bjerregaard-Andersen, Kaare, Johannesen, Hedda, Abdel-Rahman, Noha, Heggelund, Julie Elisabeth, Hoås, Helene Mykland, Abraha, Fana, Bousquet, Paula A., Høydahl, Lene Støkken, Burschowsky, Daniel, Rojas, Gertrudis, Oscarson, Stefan, Løset, Geir Åge, Krengel, Ute
Publicado 2018

Multiple system atrophy-associated oligodendroglial protein p25α stimulates formation of novel α-synuclein strain with enhanced neurodegenerative potential

por Ferreira, Nelson, Gram, Hjalte, Sorrentino, Zachary A., Gregersen, Emil, Schmidt, Sissel Ida, Reimer, Lasse, Betzer, Cristine, Perez-Gozalbo, Clara, Beltoja, Marjo, Nagaraj, Madhu, Wang, Jie, Nowak, Jan S., Dong, Mingdong, Willén, Katarina, Cholak, Ersoy, Bjerregaard-Andersen, Kaare, Mendez, Nicolas, Rabadia, Prakruti, Shahnawaz, Mohammad, Soto, Claudio, Otzen, Daniel E., Akbey, Ümit, Meyer, Morten, Giasson, Benoit I., Romero-Ramos, Marina, Jensen, Poul Henning
Publicado 2021