Causal mechanisms and balancing selection inferred from genetic associations with polycystic ovary syndrome

por Day, Felix R., Hinds, David A., Tung, Joyce Y., Stolk, Lisette, Styrkarsdottir, Unnur, Saxena, Richa, Bjonnes, Andrew, Broer, Linda, Dunger, David B., Halldorsson, Bjarni V., Lawlor, Debbie A., Laval, Guillaume, Mathieson, Iain, McCardle, Wendy L., Louwers, Yvonne, Meun, Cindy, Ring, Susan, Scott, Robert A., Sulem, Patrick, Uitterlinden, André G., Wareham, Nicholas J., Thorsteinsdottir, Unnur, Welt, Corrine, Stefansson, Kari, Laven, Joop S. E., Ong, Ken K., Perry, John R. B.
Publicado 2015

Chronotype Genetic Variant in PER2 is Associated with Intrinsic Circadian Period in Humans

por Chang, Anne-Marie, Duffy, Jeanne F., Buxton, Orfeu M., Lane, Jacqueline M., Aeschbach, Daniel, Anderson, Clare, Bjonnes, Andrew C., Cain, Sean W., Cohen, Daniel A., Frayling, Timothy M., Gooley, Joshua J., Jones, Samuel E., Klerman, Elizabeth B., Lockley, Steven W., Munch, Mirjam, Rajaratnam, Shantha M. W., Rueger, Melanie, Rutter, Martin K., Santhi, Nayantara, Scheuermaier, Karine, Van Reen, Eliza, Weedon, Michael N., Czeisler, Charles A., Scheer, Frank A. J. L., Saxena, Richa
Publicado 2019

Impact of Common Diabetes Risk Variant in MTNR1B on Sleep, Circadian, and Melatonin Physiology

por Lane, Jacqueline M., Chang, Anne-Marie, Bjonnes, Andrew C., Aeschbach, Daniel, Anderson, Clare, Cade, Brian E., Cain, Sean W., Czeisler, Charles A., Gharib, Sina A., Gooley, Joshua J., Gottlieb, Daniel J., Grant, Struan F.A., Klerman, Elizabeth B., Lauderdale, Diane S., Lockley, Steven W., Munch, Miriam, Patel, Sanjay, Punjabi, Naresh M., Rajaratnam, Shanthakumar M.W., Rueger, Melanie, St. Hilaire, Melissa A., Santhi, Nayantara, Scheuermaier, Karin, Van Reen, Eliza, Zee, Phyllis C., Shea, Steven A., Duffy, Jeanne F., Buxton, Orfeu M., Redline, Susan, Scheer, Frank A.J.L., Saxena, Richa
Publicado 2016

Genome-Wide Association Study Identifies a Novel Locus Contributing to Type 2 Diabetes Susceptibility in Sikhs of Punjabi Origin From India

por Saxena, Richa, Saleheen, Danish, Been, Latonya F., Garavito, Martha L., Braun, Timothy, Bjonnes, Andrew, Young, Robin, Ho, Weang Kee, Rasheed, Asif, Frossard, Philippe, Sim, Xueling, Hassanali, Neelam, Radha, Venkatesan, Chidambaram, Manickam, Liju, Samuel, Rees, Simon D., Ng, Daniel Peng-Keat, Wong, Tien-Yin, Yamauchi, Toshimasa, Hara, Kazuo, Tanaka, Yasushi, Hirose, Hiroshi, McCarthy, Mark I., Morris, Andrew P., Basit, Abdul, Barnett, Anthony H., Katulanda, Prasad, Matthews, David, Mohan, Viswanathan, Wander, Gurpreet S., Singh, Jai Rup, Mehra, Narinder K., Ralhan, Sarju, Kamboh, M. Ilyas, Mulvihill, John J., Maegawa, Hiroshi, Tobe, Kazuyuki, Maeda, Shiro, Cho, Yoon S., Tai, E. Shyong, Kelly, M. Ann, Chambers, John C., Kooner, Jaspal S., Kadowaki, Takashi, Deloukas, Panos, Rader, Daniel J., Danesh, John, Sanghera, Dharambir K.
Publicado 2013

An integrated clinical program and crowdsourcing strategy for genomic sequencing and Mendelian disease gene discovery

por Haghighi, Alireza, Krier, Joel B., Toth-Petroczy, Agnes, Cassa, Christopher A., Frank, Natasha Y., Carmichael, Nikkola, Fieg, Elizabeth, Bjonnes, Andrew, Mohanty, Anwoy, Briere, Lauren C., Lincoln, Sharyn, Lucia, Stephanie, Gupta, Vandana A., Söylemez, Onuralp, Sutti, Sheila, Kooshesh, Kameron, Qiu, Haiyan, Fay, Christopher J., Perroni, Victoria, Valerius, Jamie, Hanna, Meredith, Frank, Alexander, Ouahed, Jodie, Snapper, Scott B., Pantazi, Angeliki, Chopra, Sameer S., Leshchiner, Ignaty, Stitziel, Nathan O., Feldweg, Anna, Mannstadt, Michael, Loscalzo, Joseph, Sweetser, David A., Liao, Eric, Stoler, Joan M., Nowak, Catherine B., Sanchez-Lara, Pedro A., Klein, Ophir D., Perry, Hazel, Patsopoulos, Nikolaos A., Raychaudhuri, Soumya, Goessling, Wolfram, Green, Robert C., Seidman, Christine E., MacRae, Calum A., Sunyaev, Shamil R., Maas, Richard L., Vuzman, Dana
Publicado 2018

No Association of Coronary Artery Disease with X-Chromosomal Variants in Comprehensive International Meta-Analysis

por Loley, Christina, Alver, Maris, Assimes, Themistocles L., Bjonnes, Andrew, Goel, Anuj, Gustafsson, Stefan, Hernesniemi, Jussi, Hopewell, Jemma C., Kanoni, Stavroula, Kleber, Marcus E., Lau, King Wai, Lu, Yingchang, Lyytikäinen, Leo-Pekka, Nelson, Christopher P., Nikpay, Majid, Qu, Liming, Salfati, Elias, Scholz, Markus, Tukiainen, Taru, Willenborg, Christina, Won, Hong-Hee, Zeng, Lingyao, Zhang, Weihua, Anand, Sonia S., Beutner, Frank, Bottinger, Erwin P., Clarke, Robert, Dedoussis, George, Do, Ron, Esko, Tõnu, Eskola, Markku, Farrall, Martin, Gauguier, Dominique, Giedraitis, Vilmantas, Granger, Christopher B., Hall, Alistair S., Hamsten, Anders, Hazen, Stanley L., Huang, Jie, Kähönen, Mika, Kyriakou, Theodosios, Laaksonen, Reijo, Lind, Lars, Lindgren, Cecilia, Magnusson, Patrik K. E., Marouli, Eirini, Mihailov, Evelin, Morris, Andrew P., Nikus, Kjell, Pedersen, Nancy, Rallidis, Loukianos, Salomaa, Veikko, Shah, Svati H., Stewart, Alexandre F. R., Thompson, John R., Zalloua, Pierre A., Chambers, John C., Collins, Rory, Ingelsson, Erik, Iribarren, Carlos, Karhunen, Pekka J., Kooner, Jaspal S., Lehtimäki, Terho, Loos, Ruth J. F., März, Winfried, McPherson, Ruth, Metspalu, Andres, Reilly, Muredach P., Ripatti, Samuli, Sanghera, Dharambir K., Thiery, Joachim, Watkins, Hugh, Deloukas, Panos, Kathiresan, Sekar, Samani, Nilesh J., Schunkert, Heribert, Erdmann, Jeanette, König, Inke R.
Publicado 2016

A comprehensive 1000 Genomes-based genome-wide association meta-analysis of coronary artery disease

por Nikpay, Majid, Goel, Anuj, Won, Hong-Hee, Hall, Leanne M, Willenborg, Christina, Kanoni, Stavroula, Saleheen, Danish, Kyriakou, Theodosios, Nelson, Christopher P, Hopewell, Jemma C, Webb, Thomas R, Zeng, Lingyao, Dehghan, Abbas, Alver, Maris, Armasu, Sebastian M, Auro, Kirsi, Bjonnes, Andrew, Chasman, Daniel I, Chen, Shufeng, Ford, Ian, Franceschini, Nora, Gieger, Christian, Grace, Christopher, Gustafsson, Stefan, Huang, Jie, Hwang, Shih-Jen, Kim, Yun Kyoung, Kleber, Marcus E, Lau, King Wai, Lu, Xiangfeng, Lu, Yingchang, Lyytikäinen, Leo-Pekka, Mihailov, Evelin, Morrison, Alanna C, Pervjakova, Natalia, Qu, Liming, Rose, Lynda M, Salfati, Elias, Saxena, Richa, Scholz, Markus, Smith, Albert V, Tikkanen, Emmi, Uitterlinden, Andre, Yang, Xueli, Zhang, Weihua, Zhao, Wei, de Andrade, Mariza, de Vries, Paul S, van Zuydam, Natalie R, Anand, Sonia S, Bertram, Lars, Beutner, Frank, Dedoussis, George, Frossard, Philippe, Gauguier, Dominique, Goodall, Alison H, Gottesman, Omri, Haber, Marc, Han, Bok-Ghee, Huang, Jianfeng, Jalilzadeh, Shapour, Kessler, Thorsten, König, Inke R, Lannfelt, Lars, Lieb, Wolfgang, Lind, Lars, Lindgren, Cecilia M, Lokki, Marja-Liisa, Magnusson, Patrik K, Mallick, Nadeem H, Mehra, Narinder, Meitinger, Thomas, Memon, Fazal-ur-Rehman, Morris, Andrew P, Nieminen, Markku S, Pedersen, Nancy L, Peters, Annette, Rallidis, Loukianos S, Rasheed, Asif, Samuel, Maria, Shah, Svati H, Sinisalo, Juha, Stirrups, Kathleen E, Trompet, Stella, Wang, Laiyuan, Zaman, Khan S, Ardissino, Diego, Boerwinkle, Eric, Borecki, Ingrid B, Bottinger, Erwin P, Buring, Julie E, Chambers, John C, Collins, Rory, Cupples, L Adrienne, Danesh, John, Demuth, Ilja, Elosua, Roberto, Epstein, Stephen E, Esko, Tõnu, Feitosa, Mary F, Franco, Oscar H, Franzosi, Maria Grazia, Granger, Christopher B, Gu, Dongfeng, Gudnason, Vilmundur, Hall, Alistair S, Hamsten, Anders, Harris, Tamara B, Hazen, Stanley L, Hengstenberg, Christian, Hofman, Albert, Ingelsson, Erik, Iribarren, Carlos, Jukema, J Wouter, Karhunen, Pekka J, Kim, Bong-Jo, Kooner, Jaspal S, Kullo, Iftikhar J, Lehtimäki, Terho, Loos, Ruth J F, Melander, Olle, Metspalu, Andres, März, Winfried, Palmer, Colin N, Perola, Markus, Quertermous, Thomas, Rader, Daniel J, Ridker, Paul M, Ripatti, Samuli, Roberts, Robert, Salomaa, Veikko, Sanghera, Dharambir K, Schwartz, Stephen M, Seedorf, Udo, Stewart, Alexandre F, Stott, David J, Thiery, Joachim, Zalloua, Pierre A, O’Donnell, Christopher J, Reilly, Muredach P, Assimes, Themistocles L, Thompson, John R, Erdmann, Jeanette, Clarke, Robert, Watkins, Hugh, Kathiresan, Sekar, McPherson, Ruth, Deloukas, Panos, Schunkert, Heribert, Samani, Nilesh J, Farrall, Martin
Publicado 2015

Directional dominance on stature and cognition in diverse human populations

por Joshi, Peter K., Esko, Tonu, Mattsson, Hannele, Eklund, Niina, Gandin, Ilaria, Nutile, Teresa, Jackson, Anne U., Schurmann, Claudia, Smith, Albert V., Zhang, Weihua, Okada, Yukinori, Stančáková, Alena, Faul, Jessica D., Zhao, Wei, Bartz, Traci M., Concas, Maria Pina, Franceschini, Nora, Enroth, Stefan, Vitart, Veronique, Trompet, Stella, Guo, Xiuqing, Chasman, Daniel I., O’Connel, Jeffery R., Corre, Tanguy, Nongmaithem, Suraj S., Chen, Yuning, Mangino, Massimo, Ruggiero, Daniela, Traglia, Michela, Farmaki, Aliki-Eleni, Kacprowski, Tim, Bjonnes, Andrew, van der Spek, Ashley, Wu, Ying, Giri, Anil K., Yanek, Lisa R., Wang, Lihua, Hofer, Edith, Rietveld, Cornelius A., McLeod, Olga, Cornelis, Marilyn C., Pattaro, Cristian, Verweij, Niek, Baumbach, Clemens, Abdellaoui, Abdel, Warren, Helen R., Vuckovic, Dragana, Mei, Hao, Bouchard, Claude, Perry, John R.B., Cappellani, Stefania, Mirza, Saira S., Benton, Miles C., Broeckel, Ulrich, Medland, Sarah E., Lind, Penelope A., Malerba, Giovanni, Drong, Alexander, Yengo, Loic, Bielak, Lawrence F., Zhi, Degui, van der Most, Peter J., Shriner, Daniel, Mägi, Reedik, Hemani, Gibran, Karaderi, Tugce, Wang, Zhaoming, Liu, Tian, Demuth, Ilja, Zhao, Jing Hua, Meng, Weihua, Lataniotis, Lazaros, van der Laan, Sander W., Bradfield, Jonathan P., Wood, Andrew R., Bonnefond, Amelie, Ahluwalia, Tarunveer S., Hall, Leanne M., Salvi, Erika, Yazar, Seyhan, Carstensen, Lisbeth, de Haan, Hugoline G., Abney, Mark, Afzal, Uzma, Allison, Matthew A., Amin, Najaf, Asselbergs, Folkert W., Bakker, Stephan J.L., Barr, R. Graham, Baumeister, Sebastian E., Benjamin, Daniel J., Bergmann, Sven, Boerwinkle, Eric, Bottinger, Erwin P., Campbell, Archie, Chakravarti, Aravinda, Chan, Yingleong, Chanock, Stephen J., Chen, Constance, Chen, Y.-D. Ida, Collins, Francis S., Connell, John, Correa, Adolfo, Cupples, L. Adrienne, Smith, George Davey, Davies, Gail, Dörr, Marcus, Ehret, Georg, Ellis, Stephen B., Feenstra, Bjarke, Feitosa, Mary F., Ford, Ian, Fox, Caroline S., Frayling, Timothy M., Friedrich, Nele, Geller, Frank, Scotland, Generation, Gillham-Nasenya, Irina, Gottesman, Omri, Graff, Misa, Grodstein, Francine, Gu, Charles, Haley, Chris, Hammond, Christopher J., Harris, Sarah E., Harris, Tamara B., Hastie, Nicholas D., Heard-Costa, Nancy L., Heikkilä, Kauko, Hocking, Lynne J., Homuth, Georg, Hottenga, Jouke-Jan, Huang, Jinyan, Huffman, Jennifer E., Hysi, Pirro G., Ikram, M. Arfan, Ingelsson, Erik, Joensuu, Anni, Johansson, Åsa, Jousilahti, Pekka, Jukema, J. Wouter, Kähönen, Mika, Kamatani, Yoichiro, Kanoni, Stavroula, Kerr, Shona M., Khan, Nazir M., Koellinger, Philipp, Koistinen, Heikki A., Kooner, Manraj K., Kubo, Michiaki, Kuusisto, Johanna, Lahti, Jari, Launer, Lenore J., Lea, Rodney A., Lehne, Benjamin, Lehtimäki, Terho, Liewald, David C.M., Lind, Lars, Loh, Marie, Lokki, Marja-Liisa, London, Stephanie J., Loomis, Stephanie J., Loukola, Anu, Lu, Yingchang, Lumley, Thomas, Lundqvist, Annamari, Männistö, Satu, Marques-Vidal, Pedro, Masciullo, Corrado, Matchan, Angela, Mathias, Rasika A., Matsuda, Koichi, Meigs, James B., Meisinger, Christa, Meitinger, Thomas, Menni, Cristina, Mentch, Frank D., Mihailov, Evelin, Milani, Lili, Montasser, May E., Montgomery, Grant W., Morrison, Alanna, Myers, Richard H., Nadukuru, Rajiv, Navarro, Pau, Nelis, Mari, Nieminen, Markku S., Nolte, Ilja M., O’Connor, George T., Ogunniyi, Adesola, Padmanabhan, Sandosh, Palmas, Walter R., Pankow, James S., Patarcic, Inga, Pavani, Francesca, Peyser, Patricia A., Pietilainen, Kirsi, Poulter, Neil, Prokopenko, Inga, Ralhan, Sarju, Redmond, Paul, Rich, Stephen S., Rissanen, Harri, Robino, Antonietta, Rose, Lynda M., Rose, Richard, Sala, Cinzia, Salako, Babatunde, Salomaa, Veikko, Sarin, Antti-Pekka, Saxena, Richa, Schmidt, Helena, Scott, Laura J., Scott, William R., Sennblad, Bengt, Seshadri, Sudha, Sever, Peter, Shrestha, Smeeta, Smith, Blair H., Smith, Jennifer A., Soranzo, Nicole, Sotoodehnia, Nona, Southam, Lorraine, Stanton, Alice V., Stathopoulou, Maria G., Strauch, Konstantin, Strawbridge, Rona J., Suderman, Matthew J., Tandon, Nikhil, Tang, Sian-Tsun, Taylor, Kent D., Tayo, Bamidele O., Töglhofer, Anna Maria, Tomaszewski, Maciej, Tšernikova, Natalia, Tuomilehto, Jaakko, Uitterlinden, Andre G., Vaidya, Dhananjay, van Hylckama Vlieg, Astrid, van Setten, Jessica, Vasankari, Tuula, Vedantam, Sailaja, Vlachopoulou, Efthymia, Vozzi, Diego, Vuoksimaa, Eero, Waldenberger, Melanie, Ware, Erin B., Wentworth-Shields, William, Whitfield, John B., Wild, Sarah, Willemsen, Gonneke, Yajnik, Chittaranjan S., Yao, Jie, Zaza, Gianluigi, Zhu, Xiaofeng, Project, The BioBank Japan, Salem, Rany M., Melbye, Mads, Bisgaard, Hans, Samani, Nilesh J., Cusi, Daniele, Mackey, David A., Cooper, Richard S., Froguel, Philippe, Pasterkamp, Gerard, Grant, Struan F.A., Hakonarson, Hakon, Ferrucci, Luigi, Scott, Robert A., Morris, Andrew D., Palmer, Colin N.A., Dedoussis, George, Deloukas, Panos, Bertram, Lars, Lindenberger, Ulman, Berndt, Sonja I., Lindgren, Cecilia M., Timpson, Nicholas J., Tönjes, Anke, Munroe, Patricia B., Sørensen, Thorkild I.A., Rotimi, Charles N., Arnett, Donna K., Oldehinkel, Albertine J., Kardia, Sharon L.R., Balkau, Beverley, Gambaro, Giovanni, Morris, Andrew P., Eriksson, Johan G., Wright, Margie J., Martin, Nicholas G., Hunt, Steven C., Starr, John M., Deary, Ian J., Griffiths, Lyn R., Tiemeier, Henning, Pirastu, Nicola, Kaprio, Jaakko, Wareham, Nicholas J., Pérusse, Louis, Wilson, James G., Girotto, Giorgia, Caulfield, Mark J., Raitakari, Olli, Boomsma, Dorret I., Gieger, Christian, van der Harst, Pim, Hicks, Andrew A., Kraft, Peter, Sinisalo, Juha, Knekt, Paul, Johannesson, Magnus, Magnusson, Patrik K.E., Hamsten, Anders, Schmidt, Reinhold, Borecki, Ingrid B., Vartiainen, Erkki, Becker, Diane M., Bharadwaj, Dwaipayan, Mohlke, Karen L., Boehnke, Michael, van Duijn, Cornelia M., Sanghera, Dharambir K., Teumer, Alexander, Zeggini, Eleftheria, Metspalu, Andres, Gasparini, Paolo, Ulivi, Sheila, Ober, Carole, Toniolo, Daniela, Rudan, Igor, Porteous, David J., Ciullo, Marina, Spector, Tim D., Hayward, Caroline, Dupuis, Josée, Loos, Ruth J.F., Wright, Alan F., Chandak, Giriraj R., Vollenweider, Peter, Shuldiner, Alan, Ridker, Paul M., Rotter, Jerome I., Sattar, Naveed, Gyllensten, Ulf, North, Kari E., Pirastu, Mario, Psaty, Bruce M., Weir, David R., Laakso, Markku, Gudnason, Vilmundur, Takahashi, Atsushi, Chambers, John C., Kooner, Jaspal S., Strachan, David P., Campbell, Harry, Hirschhorn, Joel N., Perola, Markus, Polašek, Ozren, Wilson, James F.
Publicado 2015