Deletion of Gpr55 Results in Subtle Effects on Energy Metabolism, Motor Activity and Thermal Pain Sensation

por Bjursell, Mikael, Ryberg, Erik, Wu, Tingting, Greasley, Peter J., Bohlooly-Y, Mohammad, Hjorth, Stephan
Publicado 2016

Review article: the emerging role of genetics in precision medicine for patients with non‐alcoholic steatohepatitis

por Carlsson, Björn, Lindén, Daniel, Brolén, Gabriella, Liljeblad, Mathias, Bjursell, Mikael, Romeo, Stefano, Loomba, Rohit
Publicado 2020

Lingonberries alter the gut microbiota and prevent low-grade inflammation in high-fat diet fed mice

por Heyman-Lindén, Lovisa, Kotowska, Dorota, Sand, Elin, Bjursell, Mikael, Plaza, Merichel, Turner, Charlotta, Holm, Cecilia, Fåk, Frida, Berger, Karin
Publicado 2016

Ageing Fxr Deficient Mice Develop Increased Energy Expenditure, Improved Glucose Control and Liver Damage Resembling NASH

por Bjursell, Mikael, Wedin, Marianne, Admyre, Therése, Hermansson, Majlis, Böttcher, Gerhard, Göransson, Melker, Lindén, Daniel, Bamberg, Krister, Oscarsson, Jan, Bohlooly-Y, Mohammad
Publicado 2013

Ghrelin increases intake of rewarding food in rodents

por Egecioglu, Emil, Jerlhag, Elisabet, Salomé, Nicolas, Skibicka, Karolina P, Haage, David, Bohlooly-Y, Mohammad, Andersson, Daniel, Bjursell, Mikael, Perrissoud, Daniel, Engel, Jörgen A, Dickson, Suzanne L
Publicado 2010

Metabolic Parameters and Emotionality Are Little Affected in G-Protein Coupled Receptor 12 (Gpr12) Mutant Mice

por Frank, Elisabeth, Wu, Yizhen, Piyaratna, Naomi, Body, William James, Snikeris, Peta, South, Timothy, Gerdin, Anna-Karin, Bjursell, Mikael, Bohlooly-Y, Mohammad, Storlien, Leonard, Huang, Xu-Feng
Publicado 2012

Therapeutic Genome Editing With CRISPR/Cas9 in a Humanized Mouse Model Ameliorates α1-antitrypsin Deficiency Phenotype

por Bjursell, Mikael, Porritt, Michelle J., Ericson, Elke, Taheri-Ghahfarokhi, Amir, Clausen, Maryam, Magnusson, Lisa, Admyre, Therese, Nitsch, Roberto, Mayr, Lorenz, Aasehaug, Leif, Seeliger, Frank, Maresca, Marcello, Bohlooly-Y, Mohammad, Wiseman, John
Publicado 2018

The Beneficial Effects of n-3 Polyunsaturated Fatty Acids on Diet Induced Obesity and Impaired Glucose Control Do Not Require Gpr120

por Bjursell, Mikael, Xu, Xiufeng, Admyre, Therése, Böttcher, Gerhard, Lundin, Sofia, Nilsson, Ralf, Stone, Virginia M., Morgan, Noel G., Lam, Yan Y., Storlien, Leonard H., Lindén, Daniel, Smith, David M., Bohlooly-Y, Mohammad, Oscarsson, Jan
Publicado 2014

Monoclonal Antibody Targeting of Fibroblast Growth Factor Receptor 1c Ameliorates Obesity and Glucose Intolerance via Central Mechanisms

por Lelliott, Christopher J., Ahnmark, Andrea, Admyre, Therese, Ahlstedt, Ingela, Irving, Lorraine, Keyes, Feenagh, Patterson, Laurel, Mumphrey, Michael B., Bjursell, Mikael, Gorman, Tracy, Bohlooly-Y, Mohammad, Buchanan, Andrew, Harrison, Paula, Vaughan, Tristan, Berthoud, Hans-Rudolf, Lindén, Daniel
Publicado 2014

In vivo genome and base editing of a human PCSK9 knock-in hypercholesterolemic mouse model

por Carreras, Alba, Pane, Luna Simona, Nitsch, Roberto, Madeyski-Bengtson, Katja, Porritt, Michelle, Akcakaya, Pinar, Taheri-Ghahfarokhi, Amir, Ericson, Elke, Bjursell, Mikael, Perez-Alcazar, Marta, Seeliger, Frank, Althage, Magnus, Knöll, Ralph, Hicks, Ryan, Mayr, Lorenz M., Perkins, Rosie, Lindén, Daniel, Borén, Jan, Bohlooly-Y, Mohammad, Maresca, Marcello
Publicado 2019

AMPK activation protects against diet induced obesity through Ucp1-independent thermogenesis in subcutaneous white adipose tissue

por Pollard, Alice E., Martins, Luís, Muckett, Phillip J., Khadayate, Sanjay, Bornot, Aurélie, Clausen, Maryam, Admyre, Therese, Bjursell, Mikael, Fiadeiro, Rebeca, Wilson, Laura, Whilding, Chad, Kotiadis, Vassilios N., Duchen, Michael R., Sutton, Daniel, Penfold, Lucy, Sardini, Alessandro, Bohlooly-Y, Mohammad, Smith, David M., Read, Jon A., Snowden, Michael A., Woods, Angela, Carling, David
Publicado 2019

Pnpla3 silencing with antisense oligonucleotides ameliorates nonalcoholic steatohepatitis and fibrosis in Pnpla3 I148M knock-in mice

por Lindén, Daniel, Ahnmark, Andrea, Pingitore, Piero, Ciociola, Ester, Ahlstedt, Ingela, Andréasson, Anne-Christine, Sasidharan, Kavitha, Madeyski-Bengtson, Katja, Zurek, Magdalena, Mancina, Rosellina M., Lindblom, Anna, Bjursell, Mikael, Böttcher, Gerhard, Ståhlman, Marcus, Bohlooly-Y, Mohammad, Haynes, William G., Carlsson, Björn, Graham, Mark, Lee, Richard, Murray, Sue, Valenti, Luca, Bhanot, Sanjay, Åkerblad, Peter, Romeo, Stefano
Publicado 2019

In vivo CRISPR editing with no detectable genome-wide off-target mutations

por Akcakaya, Pinar, Bobbin, Maggie L., Guo, Jimmy A., Malagon-Lopez, Jose, Clement, Kendell, Garcia, Sara P., Fellows, Mick D., Porritt, Michelle J., Firth, Mike A., Carreras, Alba, Baccega, Tania, Seeliger, Frank, Bjursell, Mikael, Tsai, Shengdar Q., Nguyen, Nhu T., Nitsch, Roberto, Mayr, Lorenz M., Pinello, Luca, Bohlooly-Y, Mohammad, Aryee, Martin J., Maresca, Marcello, Joung, J. Keith
Publicado 2018

Ablation of PGC-1β Results in Defective Mitochondrial Activity, Thermogenesis, Hepatic Function, and Cardiac Performance

por Lelliott, Christopher J, Medina-Gomez, Gema, Petrovic, Natasa, Kis, Adrienn, Feldmann, Helena M, Bjursell, Mikael, Parker, Nadeene, Curtis, Keira, Campbell, Mark, Hu, Ping, Zhang, Dongfang, Litwin, Sheldon E, Zaha, Vlad G, Fountain, Kimberly T, Boudina, Sihem, Jimenez-Linan, Mercedes, Blount, Margaret, Lopez, Miguel, Meirhaeghe, Aline, Bohlooly-Y, Mohammad, Storlien, Leonard, Strömstedt, Maria, Snaith, Michael, Orešič, Matej, Abel, E. Dale, Cannon, Barbara, Vidal-Puig, Antonio
Publicado 2006

Adaptive Changes of the Insig1/SREBP1/SCD1 Set Point Help Adipose Tissue to Cope With Increased Storage Demands of Obesity

por Carobbio, Stefania, Hagen, Rachel M., Lelliott, Christopher J., Slawik, Marc, Medina-Gomez, Gema, Tan, Chong-Yew, Sicard, Audrey, Atherton, Helen J., Barbarroja, Nuria, Bjursell, Mikael, Bohlooly-Y, Mohammad, Virtue, Sam, Tuthill, Antoinette, Lefai, Etienne, Laville, Martine, Wu, Tingting, Considine, Robert V., Vidal, Hubert, Langin, Dominique, Oresic, Matej, Tinahones, Francisco J., Fernandez-Real, Jose Manuel, Griffin, Julian L., Sethi, Jaswinder K., López, Miguel, Vidal-Puig, Antonio
Publicado 2013

IDOL regulates systemic energy balance through control of neuronal VLDLR expression

por Lee, Stephen D., Priest, Christina, Bjursell, Mikael, Gao, Jie, Arneson, Douglas V., Ahn, In Sook, Diamante, Graciel, van Veen, J. Edward, Massa, Megan G., Calkin, Anna C., Kim, Jason, Andersén, Harriet, Rajbhandari, Prashant, Porritt, Michelle, Carreras, Alba, Ahnmark, Andrea, Seeliger, Frank, Maxvall, Ingela, Eliasson, Pernilla, Althage, Magnus, Åkerblad, Peter, Lindén, Daniel, Cole, Tracy A., Lee, Richard, Boyd, Helen, Bohlooly-Y, Mohammad, Correa, Stephanie M., Yang, Xia, Tontonoz, Peter, Hong, Cynthia
Publicado 2019