Validating and enabling phosphoglycerate dehydrogenase (PHGDH) as a target for fragment-based drug discovery in PHGDH-amplified breast cancer

por Unterlass, Judith E., Baslé, Arnaud, Blackburn, Timothy J., Tucker, Julie, Cano, Céline, Noble, Martin E.M., Curtin, Nicola J.
Publicado 2016

Characterisation of a Tip60 Specific Inhibitor, NU9056, in Prostate Cancer

por Coffey, Kelly, Blackburn, Timothy J., Cook, Susan, Golding, Bernard T., Griffin, Roger J., Hardcastle, Ian R., Hewitt, Lorraine, Huberman, Kety, McNeill, Hesta V., Newell, David R., Roche, Celine, Ryan-Munden, Claudia A., Watson, Anna, Robson, Craig N.
Publicado 2012

Parallel Optimization of Potency and Pharmacokinetics Leading to the Discovery of a Pyrrole Carboxamide ERK5 Kinase Domain Inhibitor

por Miller, Duncan C., Reuillon, Tristan, Molyneux, Lauren, Blackburn, Timothy, Cook, Simon J., Edwards, Noel, Endicott, Jane A., Golding, Bernard T., Griffin, Roger J., Hardcastle, Ian, Harnor, Suzannah J., Heptinstall, Amy, Lochhead, Pamela, Martin, Mathew P., Martin, Nick C., Myers, Stephanie, Newell, David R., Noble, Richard A., Phillips, Nicole, Rigoreau, Laurent, Thomas, Huw, Tucker, Julie A., Wang, Lan-Zhen, Waring, Michael J., Wong, Ai-Ching, Wedge, Stephen R., Noble, Martin E. M., Cano, Celine
Publicado 2022