Could Lipoprotein Lipase Play a Role in Alzheimer's Disease?

por Blain, Jean-Francois, Poirier, Judes
Publicado 2004

BACE1 Inhibitor MK-8931 Alters Formation but Not Stability of Dendritic Spines

por Blume, Tanja, Filser, Severin, Jaworska, Anna, Blain, Jean-Francois, Koenig, Gerhard, Moschke, Katrin, Lichtenthaler, Stefan F., Herms, Jochen
Publicado 2018

Granulins rescue inflammation, lysosome dysfunction, and neuropathology in a mouse model of progranulin deficiency

por Root, Jessica, Mendsaikhan, Anarmaa, Nandy, Srijita, Taylor, Georgia, Wang, Minzheng, Araujo, Ludmilla Troiano, Merino, Paola, Ryu, Danny, Holler, Christopher, Thompson, Bonne M., Astarita, Giuseppe, Blain, Jean-François, Kukar, Thomas
Publicado 2023

Characterization of FRM-36143 as a new γ-secretase modulator for the potential treatment of familial Alzheimer’s disease

por Blain, Jean-François, Bursavich, Matthew G., Freeman, Emily A., Hrdlicka, Lori A., Hodgdon, Hilliary E., Chen, Ting, Costa, Don E., Harrison, Bryce A., Kapadnis, Sudarshan, Murphy, Deirdre A., Nolan, Scott, Tu, Zhiming, Tang, Cuyue, Burnett, Duane A., Patzke, Holger, Koenig, Gerhard
Publicado 2016

Modulation of γ-secretase by EVP-0015962 reduces amyloid deposition and behavioral deficits in Tg2576 mice

por Rogers, Kathryn, Felsenstein, Kevin M, Hrdlicka, Lori, Tu, Zhiming, Albayya, Faris, Lee, Winnie, Hopp, Sarah, Miller, Mary-Jo, Spaulding, Darcie, Yang, Zhiyong, Hodgdon, Hilliary, Nolan, Scott, Wen, Melody, Costa, Don, Blain, Jean-Francois, Freeman, Emily, De Strooper, Bart, Vulsteke, Veerle, Scrocchi, Louise, Zetterberg, Henrik, Portelius, Erik, Hutter-Paier, Birgit, Havas, Daniel, Ahlijanian, Michael, Flood, Dorothy, Leventhal, Liza, Shapiro, Gideon, Patzke, Holger, Chesworth, Richard, Koenig, Gerhard
Publicado 2012