Model of care and risk factors for poor outcomes in patients on multi-drug resistant tuberculosis treatment at two facilities in eSwatini (formerly Swaziland), 2011–2013

por Verdecchia, M., Keus, K., Blankley, S., Vambe, D., Ssonko, C., Piening, T., Casas, E. C.
Publicado 2018

The application of transcriptional blood signatures to enhance our understanding of the host response to infection: the example of tuberculosis

por Blankley, Simon, Berry, Matthew Paul Reddoch, Graham, Christine M., Bloom, Chloe I., Lipman, Marc, O'Garra, Anne
Publicado 2014

Lessons learned: Retrospective assessment of outcomes and management of patients with advanced HIV disease in a semi-urban polyclinic in Epworth, Zimbabwe

por Blankley, Simon, Gashu, Tadele, Ahmad, Bilal, Belaye, Abi kebra, Ringtho, Lucia, Mesic, Anita, Zizhou, Simukai, Casas, Esther C.
Publicado 2019

Socio-demographic determinants and prevalence of Tuberculosis knowledge in three slum populations of Uganda

por Obuku, Ekwaro A, Meynell, Clea, Kiboss-Kyeyune, Jemimah, Blankley, Simon, Atuhairwe, Christine, Nabankema, Evelyn, Lab, Morris, Jeffrey, Nikki, Ndungutse, David
Publicado 2012

Identification of the Key Differential Transcriptional Responses of Human Whole Blood Following TLR2 or TLR4 Ligation In-Vitro

por Blankley, Simon, Graham, Christine M., Howes, Ashleigh, Bloom, Chloe I., Berry, Matthew P. R., Chaussabel, Damien, Pascual, Virginia, Banchereau, Jacques, Lipman, Marc, O’Garra, Anne
Publicado 2014

Differential Production of Type I IFN Determines the Reciprocal Levels of IL-10 and Proinflammatory Cytokines Produced by C57BL/6 and BALB/c Macrophages

por Howes, Ashleigh, Taubert, Christina, Blankley, Simon, Spink, Natasha, Wu, Xuemei, Graham, Christine M., Zhao, Jiawen, Saraiva, Margarida, Ricciardi-Castagnoli, Paola, Bancroft, Gregory J., O’Garra, Anne
Publicado 2016

Expression, Purification, and Biochemical Characterization of the Flavocytochrome P450 CYP505A30 from Myceliophthora thermophila

por Baker, George J., Girvan, Hazel M., Matthews, Sarah, McLean, Kirsty J., Golovanova, Marina, Waltham, Timothy N., Rigby, Stephen E. J., Nelson, David R., Blankley, Richard T., Munro, Andrew W.
Publicado 2017

Analysis of Transcriptional Signatures in Response to Listeria monocytogenes Infection Reveals Temporal Changes That Result from Type I Interferon Signaling

por Pitt, Jonathan M., Blankley, Simon, Potempa, Krzysztof, Graham, Christine M., Moreira-Teixeira, Lucia, McNab, Finlay W., Howes, Ashleigh, Stavropoulos, Evangelos, Pascual, Virginia, Banchereau, Jacques, Chaussabel, Damien, O’Garra, Anne
Publicado 2016

Catalytic Determinants of Alkene Production by the Cytochrome P450 Peroxygenase OleT(JE)

por Matthews, Sarah, Belcher, James D., Tee, Kang Lan, Girvan, Hazel M., McLean, Kirsty J., Rigby, Stephen E. J., Levy, Colin W., Leys, David, Parker, David A., Blankley, Richard T., Munro, Andrew W.
Publicado 2017

Progression of whole blood transcriptional signatures from interferon-induced to neutrophil-associated patterns in patients with severe influenza

por Dunning, Jake, Blankley, Simon, Hoang, Long T, Cox, Mike, Graham, Christine M, James, Philip L, Bloom, Chloe I, Chaussabel, Damien, Banchereau, Jacques, Brett, Stephen J., Moffatt, Miriam F, O’Garra, Anne, Openshaw, Peter JM
Publicado 2018

The Transcriptional Signature of Active Tuberculosis Reflects Symptom Status in Extra-Pulmonary and Pulmonary Tuberculosis

por Blankley, Simon, Graham, Christine M., Turner, Jacob, Berry, Matthew P. R., Bloom, Chloe I., Xu, Zhaohui, Pascual, Virginia, Banchereau, Jacques, Chaussabel, Damien, Breen, Ronan, Santis, George, Blankenship, Derek M., Lipman, Marc, O’Garra, Anne
Publicado 2016

A new strategy for hit generation: Novel in cellulo active inhibitors of CYP121A1 from Mycobacterium tuberculosis via a combined X-ray crystallographic and phenotypic screening app...

por Frederickson, Martyn, Selvam, Irwin R., Evangelopoulos, Dimitrios, McLean, Kirsty J., Katariya, Mona M., Tunnicliffe, Richard B., Campbell, Bethany, Kavanagh, Madeline E., Charoensutthivarakul, Sitthivut, Blankley, Richard T., Levy, Colin W., de Carvalho, Luiz Pedro S., Leys, David, Munro, Andrew W., Coyne, Anthony G., Abell, Chris
Publicado 2022