Targeting human SET1/MLL family of proteins

por Vedadi, Masoud, Blazer, Levi, Eram, Mohammad S., Barsyte‐Lovejoy, Dalia, Arrowsmith, Cheryl H., Hajian, Taraneh
Publicado 2017

PR Domain-containing Protein 7 (PRDM7) Is a Histone 3 Lysine 4 Trimethyltransferase

por Blazer, Levi L., Lima-Fernandes, Evelyne, Gibson, Elisa, Eram, Mohammad S., Loppnau, Peter, Arrowsmith, Cheryl H., Schapira, Matthieu, Vedadi, Masoud
Publicado 2016

A covalent peptide inhibitor of RGS4 identified in a focused one-bead, one compound library screen

por Roof, Rebecca A, Roman, David L, Clements, Samuel T, Sobczyk-Kojiro, Katarzyna, Blazer, Levi L, Ota, Shodai, Mosberg, Henry I, Neubig, Richard R
Publicado 2009

A T cell redirection platform for co-targeting dual antigens on solid tumors

por Enderle, Leonie, Shalaby, Karim H., Gorelik, Maryna, Weiss, Alexander, Blazer, Levi L., Paduch, Marcin, Cardarelli, Lia, Kossiakoff, Anthony, Adams, Jarrett J., Sidhu, Sachdev S.
Publicado 2021

Single-cell spatial transcriptomics reveals a dynamic control of metabolic zonation and liver regeneration by endothelial cell Wnt2 and Wnt9b

por Hu, Shikai, Liu, Silvia, Bian, Yu, Poddar, Minakshi, Singh, Sucha, Cao, Catherine, McGaughey, Jackson, Bell, Aaron, Blazer, Levi L., Adams, Jarret J., Sidhu, Sachdev S., Angers, Stephane, Monga, Satdarshan P.
Publicado 2022

Tailored tetravalent antibodies potently and specifically activate Wnt/Frizzled pathways in cells, organoids and mice

por Tao, Yuyong, Mis, Monika, Blazer, Levi, Ustav, Mart, Steinhart, Zachary, Chidiac, Rony, Kubarakos, Elli, O'Brien, Siobhan, Wang, Xiaomei, Jarvik, Nick, Patel, Nish, Adams, Jarrett, Moffat, Jason, Angers, Stephane, Sidhu, Sachdev S
Publicado 2019

A Norrin/Wnt surrogate antibody stimulates endothelial cell barrier function and rescues retinopathy

por Chidiac, Rony, Abedin, Md., Macleod, Graham, Yang, Andy, Thibeault, Pierre E, Blazer, Levi L, Adams, Jarrett J, Zhang, Lingling, Roehrich, Heidi, Jo, Ha‐Neul, Seshagiri, Somasekar, Sidhu, Sachdev S, Junge, Harald J, Angers, Stephane
Publicado 2021

Tetravalent SARS-CoV-2 Neutralizing Antibodies Show Enhanced Potency and Resistance to Escape Mutations

por Miersch, Shane, Li, Zhijie, Saberianfar, Reza, Ustav, Mart, Brett Case, James, Blazer, Levi, Chen, Chao, Ye, Wei, Pavlenco, Alevtina, Gorelik, Maryna, Garcia Perez, Julia, Subramania, Suryasree, Singh, Serena, Ploder, Lynda, Ganaie, Safder, Chen, Rita E., Leung, Daisy W., Pandolfi, Pier Paolo, Novelli, Giuseppe, Matusali, Giulia, Colavita, Francesca, Capobianchi, Maria R., Jain, Suresh, Gupta, J.B., Amarasinghe, Gaya K., Diamond, Michael S., Rini, James, Sidhu, Sachdev S.
Publicado 2021

Discovery of a chemical probe for PRDM9

por Allali-Hassani, Abdellah, Szewczyk, Magdalena M., Ivanochko, Danton, Organ, Shawna L., Bok, Jabez, Ho, Jessica Sook Yuin, Gay, Florence P. H., Li, Fengling, Blazer, Levi, Eram, Mohammad S., Halabelian, Levon, Dilworth, David, Luciani, Genna M., Lima-Fernandes, Evelyne, Wu, Qin, Loppnau, Peter, Palmer, Nathan, Talib, S. Zakiah A., Brown, Peter J., Schapira, Matthieu, Kaldis, Philipp, O’Hagan, Ronan C., Guccione, Ernesto, Barsyte-Lovejoy, Dalia, Arrowsmith, Cheryl H., Sanders, John M., Kattar, Solomon D., Bennett, D. Jonathan, Nicholson, Benjamin, Vedadi, Masoud
Publicado 2019