Finding the mutations that drive resistance

por Bley, Nadine
Publicado 2020

Musashi–1—A Stemness RBP for Cancer Therapy?

por Bley, Nadine, Hmedat, Ali, Müller, Simon, Rolnik, Robin, Rausch, Alexander, Lederer, Marcell, Hüttelmaier, Stefan
Publicado 2021

Oncogenic Potential of the Dual-Function Protein MEX3A

por Lederer, Marcell, Müller, Simon, Glaß, Markus, Bley, Nadine, Ihling, Christian, Sinz, Andrea, Hüttelmaier, Stefan
Publicado 2021

Stress granules are dispensable for mRNA stabilization during cellular stress

por Bley, Nadine, Lederer, Marcell, Pfalz, Birgit, Reinke, Claudia, Fuchs, Tommy, Glaß, Markus, Möller, Birgit, Hüttelmaier, Stefan
Publicado 2015

IGF2BP1, a Conserved Regulator of RNA Turnover in Cancer

por Glaß, Markus, Misiak, Danny, Bley, Nadine, Müller, Simon, Hagemann, Sven, Busch, Bianca, Rausch, Alexander, Hüttelmaier, Stefan
Publicado 2021

IGF2BP1 enhances an aggressive tumor cell phenotype by impairing miRNA-directed downregulation of oncogenic factors

por Müller, Simon, Bley, Nadine, Glaß, Markus, Busch, Bianca, Rousseau, Vanessa, Misiak, Danny, Fuchs, Tommy, Lederer, Marcell, Hüttelmaier, Stefan
Publicado 2018

The MicroRNA Landscape of MYCN-Amplified Neuroblastoma

por Misiak, Danny, Hagemann, Sven, Bell, Jessica L., Busch, Bianca, Lederer, Marcell, Bley, Nadine, Schulte, Johannes H., Hüttelmaier, Stefan
Publicado 2021

The oncogenic triangle of HMGA2, LIN28B and IGF2BP1 antagonizes tumor-suppressive actions of the let-7 family

por Busch, Bianca, Bley, Nadine, Müller, Simon, Glaß, Markus, Misiak, Danny, Lederer, Marcell, Vetter, Martina, Strauß, Hans-Georg, Thomssen, Christoph, Hüttelmaier, Stefan
Publicado 2016

IGF2BP1 induces neuroblastoma via a druggable feedforward loop with MYCN promoting 17q oncogene expression

por Hagemann, Sven, Misiak, Danny, Bell, Jessica L., Fuchs, Tommy, Lederer, Marcell I., Bley, Nadine, Hämmerle, Monika, Ghazy, Ehab, Sippl, Wolfgang, Schulte, Johannes H., Hüttelmaier, Stefan
Publicado 2023

IGF2BP1 promotes SRF-dependent transcription in cancer in a m(6)A- and miRNA-dependent manner

por Müller, Simon, Glaß, Markus, Singh, Anurag K, Haase, Jacob, Bley, Nadine, Fuchs, Tommy, Lederer, Marcell, Dahl, Andreas, Huang, Huilin, Chen, Jianjun, Posern, Guido, Hüttelmaier, Stefan
Publicado 2019

The oncofetal RNA-binding protein IGF2BP1 is a druggable, post-transcriptional super-enhancer of E2F-driven gene expression in cancer

por Müller, Simon, Bley, Nadine, Busch, Bianca, Glaß, Markus, Lederer, Marcell, Misiak, Claudia, Fuchs, Tommy, Wedler, Alice, Haase, Jacob, Bertoldo, Jean Borges, Michl, Patrick, Hüttelmaier, Stefan
Publicado 2020

Melanoma RBPome identification reveals PDIA6 as an unconventional RNA-binding protein involved in metastasis

por Mestre-Farràs, Neus, Guerrero, Santiago, Bley, Nadine, Rivero, Ezequiel, Coll, Olga, Borràs, Eva, Sabidó, Eduard, Indacochea, Alberto, Casillas-Serra, Carlos, Järvelin, Aino I, Oliva, Baldomero, Castello, Alfredo, Hüttelmaier, Stefan, Gebauer, Fátima
Publicado 2022

Synthetic circular miR-21 RNA decoys enhance tumor suppressor expression and impair tumor growth in mice

por Müller, Simon, Wedler, Alice, Breuer, Janina, Glaß, Markus, Bley, Nadine, Lederer, Marcell, Haase, Jacob, Misiak, Claudia, Fuchs, Tommy, Ottmann, Alina, Schmachtel, Tessa, Shalamova, Lyudmila, Ewe, Alexander, Aigner, Achim, Rossbach, Oliver, Hüttelmaier, Stefan
Publicado 2020

IGF2BP1 is a targetable SRC/MAPK-dependent driver of invasive growth in ovarian cancer

por Bley, Nadine, Schott, Annekatrin, Müller, Simon, Misiak, Danny, Lederer, Marcell, Fuchs, Tommy, Aßmann, Chris, Glaß, Markus, Ihling, Christian, Sinz, Andrea, Pazaitis, Nikolaos, Wickenhauser, Claudia, Vetter, Martina, Ungurs, Olga, Strauss, Hans-Georg, Thomssen, Christoph, Hüttelmaier, Stefan
Publicado 2020

HDLBP binds ER-targeted mRNAs by multivalent interactions to promote protein synthesis of transmembrane and secreted proteins

por Zinnall, Ulrike, Milek, Miha, Minia, Igor, Vieira-Vieira, Carlos H., Müller, Simon, Mastrobuoni, Guido, Hazapis, Orsalia-Georgia, Del Giudice, Simone, Schwefel, David, Bley, Nadine, Voigt, Franka, Chao, Jeffrey A., Kempa, Stefan, Hüttelmaier, Stefan, Selbach, Matthias, Landthaler, Markus
Publicado 2022