Biology of the mRNA Splicing Machinery and Its Dysregulation in Cancer Providing Therapeutic Opportunities

por Blijlevens, Maxime, Li, Jing, van Beusechem, Victor W.
Publicado 2021

Silencing Core Spliceosome Sm Gene Expression Induces a Cytotoxic Splicing Switch in the Proteasome Subunit Beta 3 mRNA in Non-Small Cell Lung Cancer Cells

por Blijlevens, Maxime, Komor, Malgorzata A., Sciarrillo, Rocco, Smit, Egbert F., Fijneman, Remond J. A., van Beusechem, Victor W.
Publicado 2020

Molecular profiling and computational network analysis of TAZ-mediated mammary tumorigenesis identifies actionable therapeutic targets

por Frangou, Costa, Li, Ying-Wei, Shen, He, Yang, Nuo, Wilson, Kayla E., Blijlevens, Maxime, Guo, Jin, Nowak, Norma J., Zhang, Jianmin
Publicado 2014

A genome‐wide siRNA screen for regulators of tumor suppressor p53 activity in human non‐small cell lung cancer cells identifies components of the RNA splicing machinery as targets...

por Siebring‐van Olst, Ellen, Blijlevens, Maxime, de Menezes, Renee X., van der Meulen‐Muileman, Ida H., Smit, Egbert F., van Beusechem, Victor W.
Publicado 2017

Sox4 Expression Confers Bladder Cancer Stem Cell Properties and Predicts for Poor Patient Outcome

por Shen, He, Blijlevens, Maxime, Yang, Nuo, Frangou, Costakis, Wilson, Kayla E., Xu, Bo, Zhang, Yinglong, Zhang, Lirui, Morrison, Carl D., Shepherd, Lori, Hu, Qiang, Zhu, Qianqian, Wang, Jianmin, Liu, Song, Zhang, Jianmin
Publicado 2015

Splicing modulation as novel therapeutic strategy against diffuse malignant peritoneal mesothelioma

por Sciarrillo, Rocco, Wojtuszkiewicz, Anna, El Hassouni, Btissame, Funel, Niccola, Gandellini, Paolo, Lagerweij, Tonny, Buonamici, Silvia, Blijlevens, Maxime, Zeeuw van der Laan, Eveline A., Zaffaroni, Nadia, Deraco, Marcello, Kusamura, Shigeki, Würdinger, Tom, Peters, Godefridus J., Molthoff, Carla F.M., Jansen, Gerrit, Kaspers, Gertjan J.L., Cloos, Jacqueline, Giovannetti, Elisa
Publicado 2018