ADAMs and ADAMTSs

por Blobel, Carl P., Apte, Suneel
Publicado 2022

Interleukin-1 Stimulates ADAM17 through a Mechanism Independent of its Cytoplasmic Domain or Phosphorylation at Threonine 735

por Hall, Katherine C., Blobel, Carl P.
Publicado 2012

The Threshold Effect: Lipopolysaccharide-Induced Inflammatory Responses in Primary Macrophages Are Differentially Regulated in an iRhom2-Dependent Manner

por Skurski, Joseph, Dixit, Garima, Blobel, Carl P., Issuree, Priya D., Maretzky, Thorsten
Publicado 2021

Conditional inactivation of the ectodomain shedding of pro-TNFα in monocytes prevents lethality from LPS-induced septic shock

por Horiuchi, Keisuke, Kimura, Tokuhiro, Okada, Yasunori, Chiba, Kazuhiro, Blobel, Carl P, Toyama, Yoshiaki
Publicado 2012

Analysis of the Conditions That Affect the Selective Processing of Endogenous Notch1 by ADAM10 and ADAM17

por Alabi, Rolake O., Lora, Jose, Celen, Arda B., Maretzky, Thorsten, Blobel, Carl P.
Publicado 2021

Epidermal ADAM17 is dispensable for Notch activation

por Groot, Arjan J., Cobzaru, Cristina, Weber, Silvio, Saftig, Paul, Blobel, Carl P., Kopan, Raphael, Vooijs, Marc, Franzke, Claus-Werner
Publicado 2013

Identification of Molecular Determinants in iRhoms1 and 2 That Contribute to the Substrate Selectivity of Stimulated ADAM17

por Zhao, Yi, Dávila, Eliud Morales, Li, Xue, Tang, Beiyu, Rabinowitsch, Ariana I., Perez-Aguilar, Jose Manuel, Blobel, Carl P.
Publicado 2022

Distinct roles for ADAM10 and ADAM17 in ectodomain shedding of six EGFR ligands

por Sahin, Umut, Weskamp, Gisela, Kelly, Kristine, Zhou, Hong-Ming, Higashiyama, Shigeki, Peschon, Jacques, Hartmann, Dieter, Saftig, Paul, Blobel, Carl P.
Publicado 2004

Evidence for cadherin-11 cleavage in the synovium and partial characterization of its mechanism

por Noss, Erika H, Watts, Gerald FM, Zocco, Davide, Keller, Tracy L, Whitman, Malcolm, Blobel, Carl P, Lee, David M, Brenner, Michael B
Publicado 2015

Role of iRhoms 1 and 2 in Endochondral Ossification

por Fang, Renpeng, Haxaire, Coline, Otero, Miguel, Lessard, Samantha, Weskamp, Gisela, McIlwain, David R., Mak, Tak W., Lichtenthaler, Stefan F., Blobel, Carl P.
Publicado 2020

Epidermal ADAM17 maintains the skin barrier by regulating EGFR ligand–dependent terminal keratinocyte differentiation

por Franzke, Claus-Werner, Cobzaru, Cristina, Triantafyllopoulou, Antigoni, Löffek, Stefanie, Horiuchi, Keisuke, Threadgill, David W., Kurz, Thomas, van Rooijen, Nico, Bruckner-Tuderman, Leena, Blobel, Carl P.
Publicado 2012

Epidermal ADAM17 maintains the skin barrier by regulating EGFR ligand-dependent terminal keratinocyte differentiation

por Franzke, Claus-Werner, Cobzaru, Cristina, Triantafyllopoulou, Antigoni, Löffek, Stefanie, Horiuchi, Keisuke, Threadgill, David W., Kurz, Thomas, van Rooijen, Nico, Bruckner-Tuderman, Leena, Blobel, Carl P.
Publicado 2012

Targeted truncation of the ADAM17 cytoplasmic domain in mice results in protein destabilization and a hypomorphic phenotype

por Lora, Jose, Weskamp, Gisela, Li, Thomas M., Maretzky, Thorsten, Shola, Dorjee T.N., Monette, Sébastien, Lichtenthaler, Stefan F., Lu, Theresa T., Yang, Chingwen, Blobel, Carl P.
Publicado 2021

Notch-RBP-J Signaling Regulates IRF8 to Promote Inflammatory Macrophage Polarization

por Xu, Haixia, Zhu, Jimmy, Smith, Sinead, Foldi, Julia, Zhao, Baohong, Chung, Allen Y., Outtz, Hasina, Kitajewski, Jan, Shi, Chao, Weber, Silvio, Saftig, Paul, Li, Yueming, Ozato, Keiko, Blobel, Carl P., Ivashkiv, Lionel B., Hu, Xiaoyu
Publicado 2012

Phytochemicals Perturb Membranes and Promiscuously Alter Protein Function

por Ingólfsson, Helgi I., Thakur, Pratima, Herold, Karl F., Hobart, E. Ashley, Ramsey, Nicole B., Periole, Xavier, de Jong, Djurre H., Zwama, Martijn, Yilmaz, Duygu, Hall, Katherine, Maretzky, Thorsten, Hemmings, Hugh C., Blobel, Carl, Marrink, Siewert J., Koçer, Armağan, Sack, Jon T., Andersen, Olaf S.
Publicado 2014

ADAM10 and ADAM17 promote SARS‐CoV‐2 cell entry and spike protein‐mediated lung cell fusion

por Jocher, Georg, Grass, Vincent, Tschirner, Sarah K, Riepler, Lydia, Breimann, Stephan, Kaya, Tuğberk, Oelsner, Madlen, Hamad, M Sabri, Hofmann, Laura I, Blobel, Carl P, Schmidt‐Weber, Carsten B, Gokce, Ozgun, Jakwerth, Constanze A, Trimpert, Jakob, Kimpel, Janine, Pichlmair, Andreas, Lichtenthaler, Stefan F
Publicado 2022

Loss of the Metalloprotease ADAM9 Leads to Cone-Rod Dystrophy in Humans and Retinal Degeneration in Mice

por Parry, David A., Toomes, Carmel, Bida, Lina, Danciger, Michael, Towns, Katherine V., McKibbin, Martin, Jacobson, Samuel G., Logan, Clare V., Ali, Manir, Bond, Jacquelyn, Chance, Rebecca, Swendeman, Steven, Daniele, Lauren L., Springell, Kelly, Adams, Matthew, Johnson, Colin A., Booth, Adam P., Jafri, Hussain, Rashid, Yasmin, Banin, Eyal, Strom, Tim M., Farber, Debora B., Sharon, Dror, Blobel, Carl P., Pugh, Edward N., Pierce, Eric A., Inglehearn, Chris F.
Publicado 2009