Phosphomimetic Modulation of eNOS Improves Myocardial Reperfusion and Mimics Cardiac Postconditioning in Mice

por Pong, Terrence, Scherrer-Crosbie, Marielle, Atochin, Dmitriy N., Bloch, Kenneth D., Huang, Paul L.
Publicado 2014

Vasoreactivity to inhaled nitric oxide with oxygen predicts long-term survival in pulmonary arterial hypertension

por Malhotra, Rajeev, Hess, Dean, Lewis, Gregory D., Bloch, Kenneth D., Waxman, Aaron B., Semigran, Marc J.
Publicado 2011

Arginase impairs hypoxic pulmonary vasoconstriction in murine endotoxemia

por Petersen, Bodil, Busch, Cornelius J., Schleifer, Grigorij, Schaack, Dominik, Lasitschka, Felix, Bloch, Kenneth D., Bloch, Donald B., Ichinose, Fumito
Publicado 2019

Gender-Specific Modulation of the Response to Arterial Injury by Soluble Guanylate Cyclase α1

por Vermeersch, Pieter, Buys, Emmanuel, Sips, Patrick, Pokreisz, Peter, Marsboom, Glenn, Gillijns, Hilde, Pellens, Marijke, Dewerchin, Mieke, Bloch, Kenneth D, Brouckaert, Peter, Janssens, Stefan
Publicado 2009

Genetic mapping of a modifier locus affecting hypertension in soluble guanylate cyclase α(1) deficient mice

por Buys, Emmanuel S, Raher, Michael J, Kirby, Andrew, Hayton, Sarah R, Tainsh, Laurel T, Sips, Patrick Y, Brouckaert, Peter, Daly, Mark J, Bloch, Kenneth D
Publicado 2011

Deletion of the Sequence Encoding the Tail Domain of the Bone Morphogenetic Protein type 2 Receptor Reveals a Bone Morphogenetic Protein 7-Specific Gain of Function

por Leyton, Patricio A., Beppu, Hideyuki, Pappas, Alexandra, Martyn, Trejeeve M., Derwall, Matthias, Baron, David M., Galdos, Rita, Bloch, Donald B., Bloch, Kenneth D.
Publicado 2013

Pharmacological preconditioning with inhaled nitric oxide (NO): Organ-specific differences in the lifetime of blood and tissue NO metabolites

por Nagasaka, Yasuko, Fernandez, Bernadette O., Steinbicker, Andrea U., Spagnolli, Ester, Malhotra, Rajeev, Bloch, Donald B., Bloch, Kenneth D., Zapol, Warren M., Feelisch, Martin
Publicado 2018

Deletion of the Murine Cytochrome P450 Cyp2j Locus by Fused BAC-Mediated Recombination Identifies a Role for Cyp2j in the Pulmonary Vascular Response to Hypoxia

por Zhou, Guo Ling, Beloiartsev, Arkadi, Yu, Binglan, Baron, David M., Zhou, Weihua, Niedra, Rasma, Lu, Naifang, Tainsh, Laurel T., Zapol, Warren M., Seed, Brian, Bloch, Kenneth D.
Publicado 2013

Cardiac soluble guanylate cyclase protects against the cardiac dysfunction induced by chronic doxorubicin treatment in mice

por Vandenwijngaert, Sara, Swinnen, Melissa, Gillijns, Hilde, Caluwé, Ellen, Tainsh, Robert E, Nathan, Daniel I, Allen, Kaitlin, Bartunek, Jozef, Brouckaert, Peter, Scherrer-Crosbie, Marielle, Bloch, Kenneth D, Janssens, Stefan P, Buys, Emmanuel S
Publicado 2015

MicroRNA miR-425 is a negative regulator of atrial natriuretic peptide

por Arora, Pankaj, Wu, Connie, Bloch, Donald B, Davis-Dusenbury, Brandi N, Spagnolli, Ester, Hata, Akiko, Vandenwijngaert, Sara, Swinnen, Melissa, Janssens, Stefan, Buys, Emmanuel S, Bloch, Kenneth D, Newton-Cheh, Christopher, Wang, Thomas J
Publicado 2013

Identification of a Small Molecule that Increases Hemoglobin Oxygen Affinity and Reduces SS Erythrocyte Sickling

por Nakagawa, Akito, Lui, Francine E., Wassaf, Dina, Yefidoff-Freedman, Revital, Casalena, Dominick, Palmer, Michelle A., Meadows, Jacqueline, Mozzarelli, Andrea, Ronda, Luca, Abdulmalik, Osheiza, Bloch, Kenneth D., Safo, Martin K., Zapol, Warren M.
Publicado 2014

sGCα(1)-deficient mice: a novel murine model of spontaneous primary open angle glaucoma

por Buys, Emmanuel S, Ko, Yu-Chieh, Hayton, Sarah, Jones, Alexander, Tainsh, Laurel, Ren, Ruiyi, Giani, Andrea, Abernathy, Emma, Gong, Haiyan, Rhee, Douglas J, Brouckaert, Peter, Gregory, Meredith, Pasquale, Louis R, Bloch, Kenneth D, Ksander, Bruce
Publicado 2011

sGCα(1)β(1 )attenuates cardiac dysfunction and mortality in murine inflammatory shock models

por Buys, Emmanuel S, Cauwels, Anje, Raher, Michael J, Passeri, Jonathan J, Hobai, Ion, Cawley, Sharon M, Rauwerdink, Kristen M, Thibault, Helene, Sips, Patrick Y, Thoonen, Robrecht, Scherrer-Crosbie, Marielle, Ichinose, Fumito, Brouckaert, Peter, Bloch, Kenneth D
Publicado 2009

Cardiovascular and pharmacological implications of haem-deficient NO-unresponsive soluble guanylate cyclase knock-in mice

por Thoonen, Robrecht, Cauwels, Anje, Decaluwe, Kelly, Geschka, Sandra, Tainsh, Robert E., Delanghe, Joris, Hochepied, Tino, De Cauwer, Lode, Rogge, Elke, Voet, Sofie, Sips, Patrick, Karas, Richard H., Bloch, Kenneth D., Vuylsteke, Marnik, Stasch, Johannes-Peter, Van de Voorde, Johan, Buys, Emmanuel S., Brouckaert, Peter
Publicado 2015

Increased Cardiac Myocyte PDE5 Levels in Human and Murine Pressure Overload Hypertrophy Contribute to Adverse LV Remodeling

por Vandenwijngaert, Sara, Pokreisz, Peter, Hermans, Hadewich, Gillijns, Hilde, Pellens, Marijke, Bax, Noortje A. M., Coppiello, Giulia, Oosterlinck, Wouter, Balogh, Agnes, Papp, Zoltan, Bouten, Carlijn V. C., Bartunek, Jozef, D'hooge, Jan, Luttun, Aernout, Verbeken, Erik, Herregods, Marie Christine, Herijgers, Paul, Bloch, Kenneth D., Janssens, Stefan
Publicado 2013

Inhibition of Bone Morphogenetic Protein Signal Transduction Prevents the Medial Vascular Calcification Associated with Matrix Gla Protein Deficiency

por Malhotra, Rajeev, Burke, Megan F., Martyn, Trejeeve, Shakartzi, Hannah R., Thayer, Timothy E., O’Rourke, Caitlin, Li, Pingcheng, Derwall, Matthias, Spagnolli, Ester, Kolodziej, Starsha A., Hoeft, Konrad, Mayeur, Claire, Jiramongkolchai, Pawina, Kumar, Ravindra, Buys, Emmanuel S., Yu, Paul B., Bloch, Kenneth D., Bloch, Donald B.
Publicado 2015

Inhaled Nitric Oxide as an Adjunctive Treatment for Cerebral Malaria in Children: A Phase II Randomized Open-Label Clinical Trial

por Mwanga-Amumpaire, Juliet, Carroll, Ryan W., Baudin, Elisabeth, Kemigisha, Elisabeth, Nampijja, Dorah, Mworozi, Kenneth, Santorino, Data, Nyehangane, Dan, Nathan, Daniel I., De Beaudrap, Pierre, Etard, Jean-François, Feelisch, Martin, Fernandez, Bernadette O., Berssenbrugge, Annie, Bangsberg, David, Bloch, Kenneth D., Boum, Yap, Zapol, Warren M.
Publicado 2015

Androgen-sensitive hypertension associated with soluble guanylate cyclase alpha1 deficiency is mediated by 20-HETE

por Vandenwijngaert, Sara, Dordea, Ana C, Garcia, Victor, Tainsh, Robert E, Nathan, Daniel I, Raher, Michael J, Allen, Kaitlin, Zhang, Fan, Lieb, Wolfgang S, Mikelman, Sarah, Kirby, Andrew, Stevens, Christine, Thoonen, Robrecht, Hindle, Allyson, Sips, Patrick Y, Malhotra, Rajeev, Daly, Mark J, Brouckaert, Peter, Bloch, Kenneth D, Schwartzman, Michal, Buys, Emmanuel S
Publicado 2015

Association of Common Variants in NPPA and NPPB with Circulating Natriuretic Peptides and Blood Pressure

por Newton-Cheh, Christopher, Larson, Martin G., Vasan, Ramachandran S., Levy, Daniel, Bloch, Kenneth D., Surti, Aarti, Guiducci, Candace, Kathiresan, Sekar, Benjamin, Emelia J., Struck, Joachim, Morgenthaler, Nils G., Bergmann, Andreas, Blankenberg, Stefan, Kee, Frank, Nilsson, Peter, Yin, Xiaoyan, Peltonen, Leena, Vartiainen, Erkki, Salomaa, Veikko, Hirschhorn, Joel N., Melander, Olle, Wang, Thomas J.
Publicado 2009

Weight Loss, Saline Loading, and the Natriuretic Peptide System

por Arora, Pankaj, Reingold, Jason, Baggish, Aaron, Guanaga, Derek P., Wu, Connie, Ghorbani, Anahita, Song, Yanna, Chen‐Tournaux, Annabel, Khan, Abigail May, Tainsh, Laurel T., Buys, Emmanuel S., Williams, Jonathan S., Heublein, Denise M., Burnett, John C., Semigran, Marc J., Bloch, Kenneth D., Scherrer‐Crosbie, Marielle, Newton‐Cheh, Christopher, Kaplan, Lee M., Wang, Thomas J.
Publicado 2015