Milk cholesterol concentration in mice is not affected by high cholesterol diet- or genetically-induced hypercholesterolaemia

por Dimova, Lidiya G., Lohuis, Mirjam A. M., Bloks, Vincent W., Tietge, Uwe J. F., Verkade, Henkjan J.
Publicado 2018

Response to Spontaneous Cholemia in C57BL/6 Mice Predisposes to Liver Cancer in NASH

por Ronda, Onne A.H.O., Bloks, Vincent W., De Boer, Jan-Freark, Kuipers, Folkert, Verkade, Henkjan J.
Publicado 2022

Hepatic Farnesoid X-Receptor Isoforms α2 and α4 Differentially Modulate Bile Salt and Lipoprotein Metabolism in Mice

por Boesjes, Marije, Bloks, Vincent W., Hageman, Jurre, Bos, Trijnie, van Dijk, Theo H., Havinga, Rick, Wolters, Henk, Jonker, Johan W., Kuipers, Folkert, Groen, Albert K.
Publicado 2014

Perinatal exposure to UDCA prevents neonatal cholestasis in Cyp2c70(-/-) mice with human-like bile acids

por de Vries, Hilde D., Palmiotti, Anna, Li, Rumei, Hovingh, Milaine V., Mulder, Niels L., Koehorst, Martijn, Bloks, Vincent W., van Zutphen, Tim, Kuipers, Folkert, de Boer, Jan Freark
Publicado 2022

Gut microbiota depletion aggravates bile acid-induced liver pathology in mice with a human-like bile acid composition

por Verkade, Esther, Shen, Wenqiang, Hovingh, Milaine V., Mulder, Niels L., de Bruyn, Krisztina, Koehorst, Martijn, de Vries, Hilde D., Bloks, Vincent W., Kuipers, Folkert, de Boer, Jan Freark
Publicado 2023

Resistance to diet-induced adiposity in cannabinoid receptor-1 deficient mice is not due to impaired adipocyte function

por Oosterveer, Maaike H, Koolman, Anniek H, de Boer, Pieter T, Bos, Trijnie, Bleeker, Aycha, van Dijk, Theo H, Bloks, Vincent W, Kuipers, Folkert, Sauer, Pieter JJ, van Dijk, Gertjan
Publicado 2011

Intestinal PPARδ protects against diet-induced obesity, insulin resistance and dyslipidemia

por Doktorova, Marcela, Zwarts, Irene, Zutphen, Tim van, Dijk, Theo H. van, Bloks, Vincent W., Harkema, Liesbeth, Bruin, Alain de, Downes, Michael, Evans, Ronald M., Verkade, Henkjan J., Jonker, Johan W.
Publicado 2017

A human-like bile acid pool induced by deletion of hepatic Cyp2c70 modulates effects of FXR activation in mice

por de Boer, Jan Freark, Verkade, Esther, Mulder, Niels L., de Vries, Hilde D., Huijkman, Nicolette, Koehorst, Martijn, Boer, Theo, Wolters, Justina C., Bloks, Vincent W., van de Sluis, Bart, Kuipers, Folkert
Publicado 2020

Male apoE*3‐Leiden.CETP mice on high‐fat high‐cholesterol diet exhibit a biphasic dyslipidemic response, mimicking the changes in plasma lipids observed through life in men

por Paalvast, Yared, Gerding, Albert, Wang, Yanan, Bloks, Vincent W., van Dijk, Theo H., Havinga, Rick, Willems van Dijk, Ko, Rensen, Patrick C. N., Bakker, Barbara M., Kuivenhoven, Jan Albert, Groen, Albert K.
Publicado 2017

Cerebral Accumulation of Dietary Derivable Plant Sterols does not Interfere with Memory and Anxiety Related Behavior in Abcg5−/− Mice

por Vanmierlo, Tim, Rutten, Kris, van Vark - van der Zee, Leonie C., Friedrichs, Silvia, Bloks, Vincent W., Blokland, Arjan, Ramaekers, Frans C., Sijbrands, Eric, Steinbusch, Harry, Prickaerts, Jos, Kuipers, Folkert, Lütjohann, Dieter, Mulder, Monique
Publicado 2011

Low production of 12α-hydroxylated bile acids prevents hepatic steatosis in Cyp2c70(−/−) mice by reducing fat absorption

por Li, Rumei, Palmiotti, Anna, de Vries, Hilde D., Hovingh, Milaine V., Koehorst, Martijn, Mulder, Niels L., Zhang, Yue, Kats, Kim, Bloks, Vincent W., Fu, Jingyuan, Verkade, Henkjan J., de Boer, Jan Freark, Kuipers, Folkert
Publicado 2021

Short‐term protein restriction at advanced age stimulates FGF21 signalling, energy expenditure and browning of white adipose tissue

por Dommerholt, Marleen B., Blankestijn, Maaike, Vieira‐Lara, Marcel A., van Dijk, Theo H., Wolters, Henk, Koster, Mirjam H., Gerding, Albert, van Os, Ronald P., Bloks, Vincent W., Bakker, Barbara M., Kruit, Janine K., Jonker, Johan W.
Publicado 2020

Bile Acid Sequestration via Colesevelam Reduces Bile Acid Hydrophobicity and Improves Liver Pathology in Cyp2c70(−/−) Mice with a Human-like Bile Acid Composition

por Palmiotti, Anna, de Vries, Hilde D., Hovingh, Milaine V., Koehorst, Martijn, Mulder, Niels L., Verkade, Esther, Veentjer, Melany K., van Dijk, Theo H., Bloks, Vincent W., Havinga, Rick, Verkade, Henkjan J., de Boer, Jan Freark, Kuipers, Folkert
Publicado 2023

Mice with a deficiency in Peroxisomal Membrane Protein 4 (PXMP4) display mild changes in hepatic lipid metabolism

por Blankestijn, Maaike, Bloks, Vincent W., Struik, Dicky, Huijkman, Nicolette, Kloosterhuis, Niels, Wolters, Justina C., Wanders, Ronald J. A., Vaz, Frédéric M., Islinger, Markus, Kuipers, Folkert, van de Sluis, Bart, Groen, Albert K., Verkade, Henkjan J., Jonker, Johan W.
Publicado 2022

Identification of Side Chain Oxidized Sterols as Novel Liver X Receptor Agonists with Therapeutic Potential in the Treatment of Cardiovascular and Neurodegenerative Diseases

por Zhan, Na, Wang, Boyang, Martens, Nikita, Liu, Yankai, Zhao, Shangge, Voortman, Gardi, van Rooij, Jeroen, Leijten, Frank, Vanmierlo, Tim, Kuipers, Folkert, Jonker, Johan W., Bloks, Vincent W., Lütjohann, Dieter, Palumbo, Marcella, Zimetti, Francesca, Adorni, Maria Pia, Liu, Hongbing, Mulder, Monique T.
Publicado 2023

The effects of bariatric surgery on clinical profile, DNA methylation, and ageing in severely obese patients

por Fraszczyk, Eliza, Luijten, Mirjam, Spijkerman, Annemieke M. W., Snieder, Harold, Wackers, Paul F. K., Bloks, Vincent W., Nicoletti, Carolina F., Nonino, Carla B., Crujeiras, Ana B., Buurman, Wim A., Greve, Jan Willem, Rensen, Sander S., Wolffenbuttel, Bruce H. R., van Vliet-Ostaptchouk, Jana V.
Publicado 2020

Hepatic Carbohydrate Response Element Binding Protein Activation Limits Nonalcoholic Fatty Liver Disease Development in a Mouse Model for Glycogen Storage Disease Type 1a

por Lei, Yu, Hoogerland, Joanne A., Bloks, Vincent W., Bos, Trijnie, Bleeker, Aycha, Wolters, Henk, Wolters, Justina C., Hijmans, Brenda S., van Dijk, Theo H., Thomas, Rachel, van Weeghel, Michel, Mithieux, Gilles, Houtkooper, Riekelt H., de Bruin, Alain, Rajas, Fabienne, Kuipers, Folkert, Oosterveer, Maaike H.
Publicado 2020

Transcriptome analysis suggests a compensatory role of the cofactors coenzyme A and NAD(+) in medium-chain acyl-CoA dehydrogenase knockout mice

por Martines, Anne-Claire M. F., Gerding, Albert, Stolle, Sarah, Vieira-Lara, Marcel A., Wolters, Justina C., Jurdzinski, Angelika, Bongiovanni, Laura, de Bruin, Alain, van der Vlies, Pieter, van der Vries, Gerben, Bloks, Vincent W., Derks, Terry G. J., Reijngoud, Dirk-Jan, Bakker, Barbara M.
Publicado 2019

Glucose‐6‐Phosphate Regulates Hepatic Bile Acid Synthesis in Mice

por Hoogerland, Joanne A., Lei, Yu, Wolters, Justina C., de Boer, Jan Freark, Bos, Trijnie, Bleeker, Aycha, Mulder, Niels L., van Dijk, Theo H., Kuivenhoven, Jan A., Rajas, Fabienne, Mithieux, Gilles, Haeusler, Rebecca A., Verkade, Henkjan J., Bloks, Vincent W., Kuipers, Folkert, Oosterveer, Maaike H.
Publicado 2019

Potential of therapeutic bile acids in the treatment of neonatal Hyperbilirubinemia

por van der Schoor, Lori W. E., Verkade, Henkjan J., Bertolini, Anna, de Wit, Sanne, Mennillo, Elvira, Rettenmeier, Eva, Weber, André A., Havinga, Rick, Valášková, Petra, Jašprová, Jana, Struik, Dicky, Bloks, Vincent W., Chen, Shujuan, Schreuder, Andrea B., Vítek, Libor, Tukey, Robert H., Jonker, Johan W.
Publicado 2021