Reduction of mitomycin C is catalysed by human recombinant NRH:quinone oxidoreductase 2 using reduced nicotinamide adenine dinucleotide as an electron donating co-factor

por Jamieson, D, Tung, A T Y, Knox, R J, Boddy, A V
Publicado 2006

Body surface area estimation in children using weight alone: application in paediatric oncology

por Sharkey, I, Boddy, A V, Wallace, H, Mycroft, J, Hollis, R, Picton, S
Publicado 2001

Estimation of glomerular filtration rate in cancer patients

por Wright, J G, Boddy, A V, Highley, M, Fenwick, J, McGill, A, Calvert, A H
Publicado 2001

Influence of pharmacogenetics on response and toxicity in breast cancer patients treated with doxorubicin and cyclophosphamide

por Bray, J, Sludden, J, Griffin, M J, Cole, M, Verrill, M, Jamieson, D, Boddy, A V
Publicado 2010

Estimation of renal function and its potential impact on carboplatin dosing in children with cancer

por Chinnaswamy, G, Cole, M, Boddy, A V, Keir, M, Price, L, Parry, A, English, M, Veal, G J
Publicado 2008

A clinical and pharmacokinetic study of the combination of carboplatin and paclitaxel for epithelial ovarian cancer.

por Siddiqui, N., Boddy, A. V., Thomas, H. D., Bailey, N. P., Robson, L., Lind, M. J., Calvert, A. H.
Publicado 1997

Platinum-DNA adduct formation in leucocytes of children in relation to pharmacokinetics after cisplatin and carboplatin therapy.

por Peng, B., Tilby, M. J., English, M. W., Price, L., Pearson, A. D., Boddy, A. V., Newell, D. R.
Publicado 1997

Molecular targeting of retinoic acid metabolism in neuroblastoma: the role of the CYP26 inhibitor R116010 in vitro and in vivo

por Armstrong, J L, Taylor, G A, Thomas, H D, Boddy, A V, Redfern, C P F, Veal, G J
Publicado 2007

Increasing the intracellular availability of all-trans retinoic acid in neuroblastoma cells

por Armstrong, J L, Ruiz, M, Boddy, A V, Redfern, C P F, Pearson, A D J, Veal, G J
Publicado 2005

Pharmacokinetics and metabolism of ifosfamide in relation to DNA damage assessed by the COMET assay in children with cancer

por Willits, I, Price, L, Parry, A, Tilby, M J, Ford, D, Cholerton, S, Pearson, A D J, Boddy, A V
Publicado 2005

Estimation of glomerular filtration rate in paediatric cancer patients using (51)CR-EDTA population pharmacokinetics

por Cole, M, Price, L, Parry, A, Keir, M J, Pearson, A D J, Boddy, A V, Veal, G J
Publicado 2004

Pharmacokinetics and metabolism of 13-cis-retinoic acid (isotretinoin) in children with high-risk neuroblastoma – a study of the United Kingdom Children's Cancer Study Group

por Veal, G J, Cole, M, Errington, J, Pearson, A D J, Foot, A B M, Whyman, G, Boddy, A V
Publicado 2007

Clinical pharmacokinetic and in vitro combination studies of nolatrexed dihydrochloride (AG337, Thymitaq(TM)) and paclitaxel

por Hughes, A N, Griffin, M J, Newell, D R, Calvert, A H, Johnston, A, Kerr, B, Lee, C, Liang, B, Boddy, A V
Publicado 2000

Thiothymidine combined with UVA as a potential novel therapy for bladder cancer

por Pridgeon, S W, Heer, R, Taylor, G A, Newell, D R, O'Toole, K, Robinson, M, Xu, Y-Z, Karran, P, Boddy, A V
Publicado 2011

Tumour cell retention of rucaparib, sustained PARP inhibition and efficacy of weekly as well as daily schedules

por Murray, J, Thomas, H, Berry, P, Kyle, S, Patterson, M, Jones, C, Los, G, Hostomsky, Z, Plummer, E R, Boddy, A V, Curtin, N J
Publicado 2014

A Phase I clinical study of cisplatin-incorporated polymeric micelles (NC-6004) in patients with solid tumours

por Plummer, R, Wilson, R H, Calvert, H, Boddy, A V, Griffin, M, Sludden, J, Tilby, M J, Eatock, M, Pearson, D G, Ottley, C J, Matsumura, Y, Kataoka, K, Nishiya, T
Publicado 2011

Phase I study of temozolomide plus paclitaxel in patients with advanced malignant melanoma and associated in vitro investigations

por Azzabi, A, Hughes, A N, Calvert, P M, Plummer, E R, Todd, R, Griffin, M J, Lind, M J, Maraveyas, A, Kelly, C, Fishwick, K, Calvert, A H, Boddy, A V
Publicado 2005

Adaptive dosing and platinum–DNA adduct formation in children receiving high-dose carboplatin for the treatment of solid tumours

por Veal, G J, Errington, J, Tilby, M J, Pearson, A D J, Foot, A B M, McDowell, H, Ellershaw, C, Pizer, B, Nowell, G M, Pearson, D G, Boddy, A V
Publicado 2007

Central nervous system penetration and enhancement of temozolomide activity in childhood medulloblastoma models by poly(ADP-ribose) polymerase inhibitor AG-014699

por Daniel, R A, Rozanska, A L, Mulligan, E A, Drew, Y, Thomas, H D, Castelbuono, D J, Hostomsky, Z, Plummer, E R, Tweddle, D A, Boddy, A V, Clifford, S C, Curtin, N J
Publicado 2010

A phase I study in paediatric patients to evaluate the safety and pharmacokinetics of SPI-77, a liposome encapsulated formulation of cisplatin

por Veal, G J, Griffin, M J, Price, E, Parry, A, Dick, G S, Little, M A, Yule, S M, Morland, B, Estlin, E J, Hale, J P, Pearson, A D J, Welbank, H, Boddy, A V
Publicado 2001