A Strategy to Refine the Phenotyping Approach and Its Implementation to Predict Drug Clearance: A Physiologically Based Pharmacokinetic Simulation Study

por Adiwidjaja, Jeffry, Boddy, Alan V., McLachlan, Andrew J.
Publicado 2018

Implementation of a Physiologically Based Pharmacokinetic Modeling Approach to Guide Optimal Dosing Regimens for Imatinib and Potential Drug Interactions in Paediatrics

por Adiwidjaja, Jeffry, Boddy, Alan V., McLachlan, Andrew J.
Publicado 2020

Physiologically Based Pharmacokinetic Modeling Approaches for Patients With SARS‐CoV‐2 Infection: A Case Study With Imatinib

por Adiwidjaja, Jeffry, Adattini, Josephine A., Boddy, Alan V., McLachlan, Andrew J.
Publicado 2022

Characterisation of the Clinical Pharmacokinetics of Actinomycin D and the Influence of ABCB1 Pharmacogenetic Variation on Actinomycin D Disposition in Children with Cancer

por Hill, Christopher R., Cole, Michael, Errington, Julie, Malik, Ghada, Boddy, Alan V., Veal, Gareth J.
Publicado 2014

Investigating the potential impact of dose banding for systemic anti-cancer therapy in the paediatric setting based on pharmacokinetic evidence

por White-Koning, Melanie, Osborne, Caroline, Paci, Angelo, Boddy, Alan V., Chatelut, Etienne, Veal, Gareth J.
Publicado 2018

Interactions between natural products and cancer treatments: underlying mechanisms and clinical importance

por Chan, Wai-Jo Jocelin, Adiwidjaja, Jeffry, McLachlan, Andrew J., Boddy, Alan V., Harnett, Joanna E.
Publicado 2023

Characterisation of the roles of ABCB1, ABCC1, ABCC2 and ABCG2 in the transport and pharmacokinetics of actinomycin D in vitro and in vivo

por Hill, Christopher R., Jamieson, David, Thomas, Huw D., Brown, Colin D.A., Boddy, Alan V., Veal, Gareth J.
Publicado 2013

A Retinol Isotope Dilution Equation Predicts Both Group and Individual Total Body Vitamin A Stores in Adults Based on Data from an Early Postdosing Blood Sample(1)(2)(3)

por Green, Michael H, Ford, Jennifer Lynn, Green, Joanne Balmer, Berry, Philip, Boddy, Alan V, Oxley, Anthony, Lietz, Georg
Publicado 2016

Plasma Retinol Kinetics and β-Carotene Bioefficacy Are Quantified by Model-Based Compartmental Analysis in Healthy Young Adults with Low Vitamin A Stores(1)(2)

por Green, Michael H, Ford, Jennifer Lynn, Oxley, Anthony, Green, Joanne Balmer, Park, Hyunjin, Berry, Philip, Boddy, Alan V, Lietz, Georg
Publicado 2016

Towards a Model-Based Dose Recommendation for Doxorubicin in Children

por Völler, Swantje, Hempel, Georg, Würthwein, Gudrun, Boddy, Alan V., Krischke, Miriam, André, Nicolas, D’Incalci, Maurizio, Bisogno, Gianni, Boos, Joachim
Publicado 2016

Development of a physiologically based pharmacokinetic model of actinomycin D in children with cancer

por Walsh, Christopher, Bonner, Jennifer J., Johnson, Trevor N., Neuhoff, Sibylle, Ghazaly, Essam A., Gribben, John G., Boddy, Alan V., Veal, Gareth J.
Publicado 2016

Cyclophosphamide pharmacokinetics and pharmacogenetics in children with B-cell non-Hodgkin's lymphoma

por Veal, Gareth J., Cole, Michael, Chinnaswamy, Girish, Sludden, Julieann, Jamieson, David, Errington, Julie, Malik, Ghada, Hill, Christopher R., Chamberlain, Thomas, Boddy, Alan V.
Publicado 2016

Pharmacokinetic and pharmacodynamic study of doxorubicin in children with cancer: results of a “European Pediatric Oncology Off-patents Medicines Consortium” trial

por Krischke, Miriam, Hempel, Georg, Völler, Swantje, André, Nicolas, D’Incalci, Maurizio, Bisogno, Gianni, Köpcke, Wolfgang, Borowski, Matthias, Herold, Ralf, Boddy, Alan V., Boos, Joachim
Publicado 2016

Formulation of Biologically-Inspired Silk-Based Drug Carriers for Pulmonary Delivery Targeted for Lung Cancer

por Kim, Sally Yunsun, Naskar, Deboki, Kundu, Subhas C., Bishop, David P., Doble, Philip A., Boddy, Alan V., Chan, Hak-Kim, Wall, Ivan B., Chrzanowski, Wojciech
Publicado 2015

Audit of Data Sharing by Pharmaceutical Companies for Anticancer Medicines Approved by the US Food and Drug Administration

por Modi, Natansh D., Abuhelwa, Ahmad Y., McKinnon, Ross A., Boddy, Alan V., Haseloff, Mark, Wiese, Michael D., Hoffmann, Tammy C., Perakslis, Eric D., Rowland, Andrew, Sorich, Michael J., Hopkins, Ashley M.
Publicado 2022

High‐resolution imaging for the detection and characterisation of circulating tumour cells from patients with oesophageal, hepatocellular, thyroid and ovarian cancers

por Dent, Barry M., Ogle, Laura F., O'Donnell, Rachel L., Hayes, Nicholas, Malik, Ujjal, Curtin, Nicola J., Boddy, Alan V., Plummer, E. Ruth, Edmondson, Richard J., Reeves, Helen L., May, Felicity E.B., Jamieson, David
Publicado 2015