Revisiting the genome-wide significance threshold for common variant GWAS

por Chen, Zhongsheng, Boehnke, Michael, Wen, Xiaoquan, Mukherjee, Bhramar
Publicado 2021

Integrating comprehensive functional annotations to boost power and accuracy in gene-based association analysis

por Quick, Corbin, Wen, Xiaoquan, Abecasis, Gonçalo, Boehnke, Michael, Kang, Hyun Min
Publicado 2020

LASER server: ancestry tracing with genotypes or sequence reads

por Taliun, Daniel, Chothani, Sonia P, Schönherr, Sebastian, Forer, Lukas, Boehnke, Michael, Abecasis, Gonçalo R, Wang, Chaolong
Publicado 2017

LocusZoom.js: interactive and embeddable visualization of genetic association study results

por Boughton, Andrew P, Welch, Ryan P, Flickinger, Matthew, VandeHaar, Peter, Taliun, Daniel, Abecasis, Gonçalo R, Boehnke, Michael
Publicado 2021

Association of 18 Confirmed Susceptibility Loci for Type 2 Diabetes With Indices of Insulin Release, Proinsulin Conversion, and Insulin Sensitivity in 5,327 Nondiabetic Finnish Men

por Stančáková, Alena, Kuulasmaa, Teemu, Paananen, Jussi, Jackson, Anne U., Bonnycastle, Lori L., Collins, Francis S., Boehnke, Michael, Kuusisto, Johanna, Laakso, Markku
Publicado 2009

LocusZoom: regional visualization of genome-wide association scan results

por Pruim, Randall J., Welch, Ryan P., Sanna, Serena, Teslovich, Tanya M., Chines, Peter S., Gliedt, Terry P., Boehnke, Michael, Abecasis, Gonçalo R., Willer, Cristen J.
Publicado 2010

Estimating Hepatic Glucokinase Activity Using a Simple Model of Lactate Kinetics

por Stefanovski, Darko, Youn, Jang H., Rees, Matthew, Watanabe, Richard M., Ader, Marilyn, Ionut, Viorica, Jackson, Anne U., Boehnke, Michael, Collins, Francis S., Bergman, Richard N.
Publicado 2012

Congenital cataracts: de novo gene conversion event in CRYBB2

por Garnai, Sarah J., Huyghe, Jeroen R., Reed, David M., Scott, Kathleen M., Liebmann, Jeffrey M., Boehnke, Michael, Richards, Julia E., Ritch, Robert, Pawar, Hemant
Publicado 2014

Sequencing and imputation in GWAS: Cost‐effective strategies to increase power and genomic coverage across diverse populations

por Quick, Corbin, Anugu, Pramod, Musani, Solomon, Weiss, Scott T., Burchard, Esteban G., White, Marquitta J., Keys, Kevin L., Cucca, Francesco, Sidore, Carlo, Boehnke, Michael, Fuchsberger, Christian
Publicado 2020

Ancestry-agnostic estimation of DNA sample contamination from sequence reads

por Zhang, Fan, Flickinger, Matthew, Taliun, Sarah A. Gagliano, Abecasis, Gonçalo R., Scott, Laura J., McCaroll, Steven A., Pato, Carlos N., Boehnke, Michael, Kang, Hyun Min
Publicado 2020

Extremely rare variants reveal patterns of germline mutation rate heterogeneity in humans

por Carlson, Jedidiah, Locke, Adam E., Flickinger, Matthew, Zawistowski, Matthew, Levy, Shawn, Myers, Richard M., Boehnke, Michael, Kang, Hyun Min, Scott, Laura J., Li, Jun Z., Zöllner, Sebastian
Publicado 2018

The Power of Gene-Based Rare Variant Methods to Detect Disease-Associated Variation and Test Hypotheses About Complex Disease

por Moutsianas, Loukas, Agarwala, Vineeta, Fuchsberger, Christian, Flannick, Jason, Rivas, Manuel A., Gaulton, Kyle J., Albers, Patrick K., McVean, Gil, Boehnke, Michael, Altshuler, David, McCarthy, Mark I.
Publicado 2015

Genetic evidence that high BMI in childhood has a protective effect on intermediate diabetes traits, including measures of insulin sensitivity and secretion, after accounting for B...

por Hawkes, Gareth, Beaumont, Robin N., Tyrrell, Jessica, Power, Grace M., Wood, Andrew, Laakso, Markku, Fernandes Silva, Lilian, Boehnke, Michael, Yin, Xianyong, Richardson, Tom G., Smith, George Davey, Frayling, Timothy M.
Publicado 2023

Effects of 34 Risk Loci for Type 2 Diabetes or Hyperglycemia on Lipoprotein Subclasses and Their Composition in 6,580 Nondiabetic Finnish Men

por Stančáková, Alena, Paananen, Jussi, Soininen, Pasi, Kangas, Antti J., Bonnycastle, Lori L., Morken, Mario A., Collins, Francis S., Jackson, Anne U., Boehnke, Michael L., Kuusisto, Johanna, Ala-Korpela, Mika, Laakso, Markku
Publicado 2011

Genetic evidence that high BMI in childhood has a protective effect on intermediate diabetes traits, including measures of insulin sensitivity and secretion

por Hawkes, Gareth, Beaumont, Robin N, Tyrrell, Jessica, Power, Grace M, Wood, Andrew, Laakso, Markku, Silva, Lilian Fernandes, Boehnke, Michael, Yin, Xianyong, Richardson, Tom G, Smith, George Davey, Frayling, Timothy M
Publicado 2023

Imputation-Aware Tag SNP Selection To Improve Power for Large-Scale, Multi-ethnic Association Studies

por Wojcik, Genevieve L., Fuchsberger, Christian, Taliun, Daniel, Welch, Ryan, Martin, Alicia R, Shringarpure, Suyash, Carlson, Christopher S., Abecasis, Goncalo, Kang, Hyun Min, Boehnke, Michael, Bustamante, Carlos D., Gignoux, Christopher R., Kenny, Eimear E.
Publicado 2018

Transferability of Type 2 Diabetes Implicated Loci in Multi-Ethnic Cohorts from Southeast Asia

por Sim, Xueling, Ong, Rick Twee-Hee, Suo, Chen, Tay, Wan-Ting, Liu, Jianjun, Ng, Daniel Peng-Keat, Boehnke, Michael, Chia, Kee-Seng, Wong, Tien-Yin, Seielstad, Mark, Teo, Yik-Ying, Tai, E-Shyong
Publicado 2011

The Michigan Genomics Initiative: A biobank linking genotypes and electronic clinical records in Michigan Medicine patients

por Zawistowski, Matthew, Fritsche, Lars G., Pandit, Anita, Vanderwerff, Brett, Patil, Snehal, Schmidt, Ellen M., VandeHaar, Peter, Willer, Cristen J., Brummett, Chad M., Kheterpal, Sachin, Zhou, Xiang, Boehnke, Michael, Abecasis, Gonçalo R., Zöllner, Sebastian
Publicado 2023

Type 2 diabetes genetic loci informed by multi-trait associations point to disease mechanisms and subtypes: A soft clustering analysis

por Udler, Miriam S., Kim, Jaegil, von Grotthuss, Marcin, Bonàs-Guarch, Sílvia, Cole, Joanne B., Chiou, Joshua, Boehnke, Michael, Laakso, Markku, Atzmon, Gil, Glaser, Benjamin, Mercader, Josep M., Gaulton, Kyle, Flannick, Jason, Getz, Gad, Florez, Jose C.
Publicado 2018

Trans-ancestry Fine Mapping and Molecular Assays Identify Regulatory Variants at the ANGPTL8 HDL-C GWAS Locus

por Cannon, Maren E., Duan, Qing, Wu, Ying, Zeynalzadeh, Monica, Xu, Zheng, Kangas, Antti J., Soininen, Pasi, Ala-Korpela, Mika, Civelek, Mete, Lusis, Aldons J., Kuusisto, Johanna, Collins, Francis S., Boehnke, Michael, Tang, Hua, Laakso, Markku, Li, Yun, Mohlke, Karen L.
Publicado 2017