Plasma proteomics identifies CRTAC1 as a biomarker for osteoarthritis severity and progression

por Szilagyi, Ingrid A, Vallerga, Costanza L, Boer, Cindy G, Schiphof, Dieuwke, Ikram, M Arfan, Bierma-Zeinstra, Sita M A, van Meurs, Joyce B J
Publicado 2022

Vitamin K antagonist anticoagulant usage is associated with increased incidence and progression of osteoarthritis

por Boer, Cindy G, Szilagyi, Ingrid, Nguyen, N Long, Neogi, Tuhina, Meulenbelt, Ingrid, Ikram, M Arfan, Uitterlinden, André G, Bierma-Zeinstra, Sita, Stricker, Bruno H, van Meurs, Joyce B
Publicado 2021

Using multivariable Mendelian randomization to estimate the causal effect of bone mineral density on osteoarthritis risk, independently of body mass index

por Hartley, April, Sanderson, Eleanor, Granell, Raquel, Paternoster, Lavinia, Zheng, Jie, Smith, George Davey, Southam, Lorraine, Hatzikotoulas, Konstantinos, Boer, Cindy G, van Meurs, Joyce, Zeggini, Eleftheria, Gregson, Celia L, Tobias, Jon H
Publicado 2021

Risk Assessment for Hip and Knee Osteoarthritis Using Polygenic Risk Scores

por Sedaghati‐Khayat, Bahar, Boer, Cindy G., Runhaar, Jos, Bierma‐Zeinstra, Sita M. A., Broer, Linda, Ikram, M. Arfan, Zeggini, Eleftheria, Uitterlinden, André G., van Rooij, Jeroen G. J., van Meurs, Joyce B. J.
Publicado 2022

WNT/beta-catenin signalling interrupts a senescence-induction cascade in human mesenchymal stem cells that restricts their expansion

por Lehmann, Johannes, Narcisi, Roberto, Franceschini, Natasja, Chatzivasileiou, Danai, Boer, Cindy G., Koevoet, Wendy J. L. M., Putavet, Diana, Drabek, Dubravka, van Haperen, Rien, de Keizer, Peter L. J., van Osch, Gerjo J. V. M., ten Berge, Derk
Publicado 2022

Intestinal microbiome composition and its relation to joint pain and inflammation

por Boer, Cindy G., Radjabzadeh, Djawad, Medina-Gomez, Carolina, Garmaeva, Sanzhima, Schiphof, Dieuwke, Arp, Pascal, Koet, Thomas, Kurilshikov, Alexander, Fu, Jingyuan, Ikram, M. Arfan, Bierma-Zeinstra, Sita, Uitterlinden, André G., Kraaij, Robert, Zhernakova, Alexandra, van Meurs, Joyce B. J.
Publicado 2019

A Genome‐Wide Association Study Meta‐Analysis of Alpha Angle Suggests Cam‐Type Morphology May Be a Specific Feature of Hip Osteoarthritis in Older Adults

por Faber, Benjamin G., Frysz, Monika, Hartley, April E., Ebsim, Raja, Boer, Cindy G., Saunders, Fiona R., Gregory, Jennifer S., Aspden, Richard M., Harvey, Nicholas C., Southam, Lorraine, Giles, William, Le Maitre, Christine L., Wilkinson, J. Mark, van Meurs, Joyce B. J., Zeggini, Eleftheria, Cootes, Timothy, Lindner, Claudia, Kemp, John P., Davey Smith, George, Tobias, Jonathan H.
Publicado 2023

Diversity, compositional and functional differences between gut microbiota of children and adults

por Radjabzadeh, Djawad, Boer, Cindy G., Beth, Sanne A., van der Wal, Pelle, Kiefte-De Jong, Jessica C., Jansen, Michelle A. E., Konstantinov, Sergey R., Peppelenbosch, Maikel P., Hays, John P., Jaddoe, Vincent W. V., Ikram, M. Arfan, Rivadeneira, Fernando, van Meurs, Joyce B. J., Uitterlinden, André G., Medina-Gomez, Carolina, Moll, Henriette A., Kraaij, Robert
Publicado 2020

The identification of distinct protective and susceptibility mechanisms for hip osteoarthritis: findings from a genome-wide association study meta-analysis of minimum joint space w...

por Faber, Benjamin G., Frysz, Monika, Boer, Cindy G., Evans, Daniel S., Ebsim, Raja, Flynn, Kaitlyn A., Lundberg, Mischa, Southam, Lorraine, Hartley, April, Saunders, Fiona R., Lindner, Claudia, Gregory, Jennifer S., Aspden, Richard M., Lane, Nancy E., Harvey, Nicholas C., Evans, David M., Zeggini, Eleftheria, Davey Smith, George, Cootes, Timothy, Van Meurs, Joyce, Kemp, John P., Tobias, Jonathan H.
Publicado 2023

Genome-wide analyses using UK Biobank data provide insights into the genetic architecture of osteoarthritis

por Zengini, Eleni, Hatzikotoulas, Konstantinos, Tachmazidou, Ioanna, Steinberg, Julia, Hartwig, Fernando P., Southam, Lorraine, Hackinger, Sophie, Boer, Cindy G., Styrkarsdottir, Unnur, Gilly, Arthur, Suveges, Daniel, Killian, Britt, Ingvarsson, Thorvaldur, Jonsson, Helgi, Babis, George C., McCaskie, Andrew, Uitterlinden, Andre G., van Meurs, Joyce B. J., Thorsteinsdottir, Unnur, Stefansson, Kari, Smith, George Davey, Wilkinson, Jeremy M., Zeggini, Eleftheria
Publicado 2018

Genome-wide association study identifies nine novel loci for 2D:4D finger ratio, a putative retrospective biomarker of testosterone exposure in utero

por Warrington, Nicole M, Shevroja, Enisa, Hemani, Gibran, Hysi, Pirro G, Jiang, Yunxuan, Auton, Adam, Boer, Cindy G, Mangino, Massimo, Wang, Carol A, Kemp, John P, McMahon, George, Medina-Gomez, Carolina, Hickey, Martha, Trajanoska, Katerina, Wolke, Dieter, Ikram, M Arfan, Montgomery, Grant W, Felix, Janine F, Wright, Margaret J, Mackey, David A, Jaddoe, Vincent W, Martin, Nicholas G, Tung, Joyce Y, Davey Smith, George, Pennell, Craig E, Spector, Tim D, van Meurs, Joyce, Rivadeneira, Fernando, Medland, Sarah E, Evans, David M
Publicado 2018

Bivariate genome-wide association meta-analysis of pediatric musculoskeletal traits reveals pleiotropic effects at the SREBF1/TOM1L2 locus

por Medina-Gomez, Carolina, Kemp, John P., Dimou, Niki L., Kreiner, Eskil, Chesi, Alessandra, Zemel, Babette S., Bønnelykke, Klaus, Boer, Cindy G., Ahluwalia, Tarunveer S., Bisgaard, Hans, Evangelou, Evangelos, Heppe, Denise H. M., Bonewald, Lynda F., Gorski, Jeffrey P., Ghanbari, Mohsen, Demissie, Serkalem, Duque, Gustavo, Maurano, Matthew T., Kiel, Douglas P., Hsu, Yi-Hsiang, C.J. van der Eerden, Bram, Ackert-Bicknell, Cheryl, Reppe, Sjur, Gautvik, Kaare M., Raastad, Truls, Karasik, David, van de Peppel, Jeroen, Jaddoe, Vincent W. V., Uitterlinden, André G., Tobias, Jonathan H., Grant, Struan F.A., Bagos, Pantelis G., Evans, David M., Rivadeneira, Fernando
Publicado 2017

Genome-wide meta-analysis of 158,000 individuals of European ancestry identifies three loci associated with chronic back pain

por Suri, Pradeep, Palmer, Melody R., Tsepilov, Yakov A., Freidin, Maxim B., Boer, Cindy G., Yau, Michelle S., Evans, Daniel S., Gelemanovic, Andrea, Bartz, Traci M., Nethander, Maria, Arbeeva, Liubov, Karssen, Lennart, Neogi, Tuhina, Campbell, Archie, Mellstrom, Dan, Ohlsson, Claes, Marshall, Lynn M., Orwoll, Eric, Uitterlinden, Andre, Rotter, Jerome I., Lauc, Gordan, Psaty, Bruce M., Karlsson, Magnus K., Lane, Nancy E., Jarvik, Gail P., Polasek, Ozren, Hochberg, Marc, Jordan, Joanne M., Van Meurs, Joyce B. J., Jackson, Rebecca, Nielson, Carrie M., Mitchell, Braxton D., Smith, Blair H., Hayward, Caroline, Smith, Nicholas L., Aulchenko, Yurii S., Williams, Frances M. K.
Publicado 2018

Novel Genetic Variants for Cartilage Thickness and Hip Osteoarthritis

por Castaño-Betancourt, Martha C., Evans, Dan S., Ramos, Yolande F. M., Boer, Cindy G., Metrustry, Sarah, Liu, Youfang, den Hollander, Wouter, van Rooij, Jeroen, Kraus, Virginia B., Yau, Michelle S., Mitchell, Braxton D., Muir, Kenneth, Hofman, Albert, Doherty, Michael, Doherty, Sally, Zhang, Weiya, Kraaij, Robert, Rivadeneira, Fernando, Barrett-Connor, Elizabeth, Maciewicz, Rose A., Arden, Nigel, Nelissen, Rob G. H. H., Kloppenburg, Margreet, Jordan, Joanne M., Nevitt, Michael C., Slagboom, Eline P., Hart, Deborah J., Lafeber, Floris, Styrkarsdottir, Unnur, Zeggini, Eleftheria, Evangelou, Evangelos, Spector, Tim D., Uitterlinden, Andre G., Lane, Nancy E., Meulenbelt, Ingrid, Valdes, Ana M., van Meurs, Joyce B. J.
Publicado 2016

GWAS of bone size yields twelve loci that also affect height, BMD, osteoarthritis or fractures

por Styrkarsdottir, Unnur, Stefansson, Olafur A., Gunnarsdottir, Kristbjorg, Thorleifsson, Gudmar, Lund, Sigrun H., Stefansdottir, Lilja, Juliusson, Kristinn, Agustsdottir, Arna B., Zink, Florian, Halldorsson, Gisli H., Ivarsdottir, Erna V., Benonisdottir, Stefania, Jonsson, Hakon, Gylfason, Arnaldur, Norland, Kristjan, Trajanoska, Katerina, Boer, Cindy G., Southam, Lorraine, Leung, Jason C. S., Tang, Nelson L. S., Kwok, Timothy C. Y., Lee, Jenny S. W., Ho, Suzanne C., Byrjalsen, Inger, Center, Jacqueline R., Lee, Seung Hun, Koh, Jung-Min, Lohmander, L. Stefan, Ho-Pham, Lan T., Nguyen, Tuan V., Eisman, John A., Woo, Jean, Leung, Ping-C., Loughlin, John, Zeggini, Eleftheria, Christiansen, Claus, Rivadeneira, Fernando, van Meurs, Joyce, Uitterlinden, Andre G., Mogensen, Brynjolfur, Jonsson, Helgi, Ingvarsson, Thorvaldur, Sigurdsson, Gunnar, Benediktsson, Rafn, Sulem, Patrick, Jonsdottir, Ingileif, Masson, Gisli, Holm, Hilma, Norddahl, Gudmundur L., Thorsteinsdottir, Unnur, Gudbjartsson, Daniel F., Stefansson, Kari
Publicado 2019

Publisher Correction: GWAS of bone size yields twelve loci that also affect height, BMD, osteoarthritis or fractures

por Styrkarsdottir, Unnur, Stefansson, Olafur A., Gunnarsdottir, Kristbjorg, Thorleifsson, Gudmar, Lund, Sigrun H., Stefansdottir, Lilja, Juliusson, Kristinn, Agustsdottir, Arna B., Zink, Florian, Halldorsson, Gisli H., Ivarsdottir, Erna V., Benonisdottir, Stefania, Jonsson, Hakon, Gylfason, Arnaldur, Norland, Kristjan, Trajanoska, Katerina, Boer, Cindy G., Southam, Lorraine, Leung, Jason C. S., Tang, Nelson L. S., Kwok, Timothy C. Y., Lee, Jenny S. W., Ho, Suzanne C., Byrjalsen, Inger, Center, Jacqueline R., Lee, Seung Hun, Koh, Jung-Min, Lohmander, L. Stefan, Ho-Pham, Lan T., Nguyen, Tuan V., Eisman, John A., Woo, Jean, Leung, Ping-C., Loughlin, John, Zeggini, Eleftheria, Christiansen, Claus, Rivadeneira, Fernando, van Meurs, Joyce, Uitterlinden, Andre G., Mogensen, Brynjolfur, Jonsson, Helgi, Ingvarsson, Thorvaldur, Sigurdsson, Gunnar, Benediktsson, Rafn, Sulem, Patrick, Jonsdottir, Ingileif, Masson, Gisli, Holm, Hilma, Norddahl, Gudmundur L., Thorsteinsdottir, Unnur, Gudbjartsson, Daniel F., Stefansson, Kari
Publicado 2019

Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations

por Boer, Cindy G., Hatzikotoulas, Konstantinos, Southam, Lorraine, Stefánsdóttir, Lilja, Zhang, Yanfei, Coutinho de Almeida, Rodrigo, Wu, Tian T., Zheng, Jie, Hartley, April, Teder-Laving, Maris, Skogholt, Anne Heidi, Terao, Chikashi, Zengini, Eleni, Alexiadis, George, Barysenka, Andrei, Bjornsdottir, Gyda, Gabrielsen, Maiken E., Gilly, Arthur, Ingvarsson, Thorvaldur, Johnsen, Marianne B., Jonsson, Helgi, Kloppenburg, Margreet, Luetge, Almut, Lund, Sigrun H., Mägi, Reedik, Mangino, Massimo, Nelissen, Rob R.G.H.H., Shivakumar, Manu, Steinberg, Julia, Takuwa, Hiroshi, Thomas, Laurent F., Tuerlings, Margo, Babis, George C., Cheung, Jason Pui Yin, Kang, Jae Hee, Kraft, Peter, Lietman, Steven A., Samartzis, Dino, Slagboom, P. Eline, Stefansson, Kari, Thorsteinsdottir, Unnur, Tobias, Jonathan H., Uitterlinden, André G., Winsvold, Bendik, Zwart, John-Anker, Davey Smith, George, Sham, Pak Chung, Thorleifsson, Gudmar, Gaunt, Tom R., Morris, Andrew P., Valdes, Ana M., Tsezou, Aspasia, Cheah, Kathryn S.E., Ikegawa, Shiro, Hveem, Kristian, Esko, Tõnu, Wilkinson, J. Mark, Meulenbelt, Ingrid, Lee, Ming Ta Michael, van Meurs, Joyce B.J., Styrkársdóttir, Unnur, Zeggini, Eleftheria
Publicado 2021

Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations

por Boer, Cindy G., Hatzikotoulas, Konstantinos, Southam, Lorraine, Stefánsdóttir, Lilja, Zhang, Yanfei, Coutinho de Almeida, Rodrigo, Wu, Tian T., Zheng, Jie, Hartley, April, Teder-Laving, Maris, Skogholt, Anne Heidi, Terao, Chikashi, Zengini, Eleni, Alexiadis, George, Barysenka, Andrei, Bjornsdottir, Gyda, Gabrielsen, Maiken E., Gilly, Arthur, Ingvarsson, Thorvaldur, Johnsen, Marianne B., Jonsson, Helgi, Kloppenburg, Margreet, Luetge, Almut, Lund, Sigrun H., Mägi, Reedik, Mangino, Massimo, Nelissen, Rob R.G.H.H., Shivakumar, Manu, Steinberg, Julia, Takuwa, Hiroshi, Thomas, Laurent F., Tuerlings, Margo, Babis, George C., Yin Cheung, Jason Pui, Kang, Jae Hee, Kraft, Peter, Lietman, Steven A., Samartzis, Dino, Slagboom, P. Eline, Stefansson, Kari, Thorsteinsdottir, Unnur, Tobias, Jonathan H., Uitterlinden, André G., Winsvold, Bendik, Zwart, John-Anker, Smith, George Davey, Sham, Pak Chung, Thorleifsson, Gudmar, Gaunt, Tom R., Morris, Andrew P., Valdes, Ana M., Tsezou, Aspasia, Cheah, Kathryn S.E., Ikegawa, Shiro, Hveem, Kristian, Esko, Tõnu, Wilkinson, J. Mark, Meulenbelt, Ingrid, Michael Lee, Ming Ta, van Meurs, Joyce B.J., Styrkársdóttir, Unnur, Zeggini, Eleftheria
Publicado 2021