The Difference a Single Atom Can Make: Synthesis and Design at the Chemistry–Biology Interface

por Boger, Dale L.
Publicado 2017

Total Syntheses of (−)-Pyrimidoblamic Acid and P-3A

por Duerfeldt, Adam S., Boger, Dale L.
Publicado 2014

Total Syntheses of (−)-Kopsifoline D and (−)-Deoxoapodine: Divergent Total Synthesis via Late-Stage Key Strategic Bond Formation

por Lee, Kiyoun, Boger, Dale L.
Publicado 2014

Asymmetric Synthesis of a CBI-Based Cyclic N-Acyl O-Amino Phenol Duocarmycin Prodrug

por Uematsu, Mika, Boger, Dale L.
Publicado 2014

Total Synthesis of Vinblastine, Related Natural Products, and Key Analogues and Development of Inspired Methodology Suitable for the Systematic Study of Their Structure–Function Pr...

por Sears, Justin E., Boger, Dale L.
Publicado 2015

Design, Synthesis, and Characterization of α-Ketoheterocycles That Additionally Target the Cytosolic Port Cys269 of Fatty Acid Amide Hydrolase

por Otrubova, Katerina, Cravatt, Benjamin F., Boger, Dale L.
Publicado 2014

Total Synthesis of [Ψ[C(=NH)NH]Tpg(4)]Vancomycin and its (4-Chlorobiphenyl)methyl Derivative: Impact of Peripheral Modifications on Vancomycin Analogues Redesigned for Dual d-Ala-d...

por Okano, Akinori, Nakayama, Atsushi, Schammel, Alex W., Boger, Dale L.
Publicado 2014

Mechanistic Insights into the Reaction of Amidines with 1,2,3-Triazines and 1,2,3,5-Tetrazines

por Wu, Zhi-Chen, Houk, K. N., Boger, Dale L., Svatunek, Dennis
Publicado 2022

Cycloadditions of Noncomplementary Substituted 1,2,3-Triazines

por Anderson, Erin D., Duerfeldt, Adam S., Zhu, Kaicheng, Glinkerman, Christopher M., Boger, Dale L.
Publicado 2014

Structural evolution of a DNA repair self-resistance mechanism targeting genotoxic secondary metabolites

por Mullins, Elwood A., Dorival, Jonathan, Tang, Gong-Li, Boger, Dale L., Eichman, Brandt F.
Publicado 2021

Enzymatic Glycosylation of Vancomycin Aglycon: Completion of a Total Synthesis of Vancomycin and N- and C-Terminus Substituent Effects of the Aglycon Substrate

por Nakayama, Atsushi, Okano, Akinori, Feng, Yiqing, Collins, James C., Collins, Karen C., Walsh, Christopher T., Boger, Dale L.
Publicado 2014

The Sleep-inducing Lipid Oleamide Deconvolutes Gap Junction Communication and Calcium Wave Transmission in Glial Cells

por Guan, Xiaojun, Cravatt, Benjamin F., Ehring, George R., Hall, James E., Boger, Dale L., Lerner, Richard A., Gilula, Norton B.
Publicado 1997

Total synthesis of a key series of vinblastines modified at C4 that define the importance and surprising trends in activity

por Yang, Shouliang, Sankar, Kuppusamy, Skepper, Colin K., Barker, Timothy J., Lukesh III, John C., Brody, Daniel M., Brütsch, Manuela M., Boger, Dale L.
Publicado 2017

Target-Based Screen Against a Periplasmic Serine Protease That Regulates Intrabacterial pH Homeostasis in Mycobacterium tuberculosis

por Zhao, Nan, Darby, Crystal M., Small, Jennifer, Bachovchin, Daniel A., Jiang, Xiuju, Burns-Huang, Kristin E., Botella, Helene, Ehrt, Sabine, Boger, Dale L., Anderson, Erin D., Cravatt, Benjamin F., Speers, Anna E., Fernandez-Vega, Virneliz, Hodder, Peter S., Eberhart, Christina, Rosen, Hugh, Spicer, Timothy P., Nathan, Carl F.
Publicado 2014

Discovery of small-molecule enzyme activators by activity-based protein profiling

por Kok, Bernard P., Ghimire, Srijana, Kim, Woojoo, Chatterjee, Shreyosree, Johns, Tyler, Kitamura, Seiya, Eberhardt, Jerome, Ogasawara, Daisuke, Xu, Janice, Sukiasyan, Ara, Kim, Sean M., Godio, Cristina, Bittencourt, Julia M., Cameron, Michael, Galmozzi, Andrea, Forli, Stefano, Wolan, Dennis W., Cravatt, Benjamin F., Boger, Dale L., Saez, Enrique
Publicado 2020