DNA-Related Pathways Defective in Human Premature Aging

por Bohr, Vilhelm A.
Publicado 2002

Human premature aging, DNA repair and RecQ helicases

por Brosh, Robert M., Bohr, Vilhelm A.
Publicado 2007

Slow mitochondrial repair of 5′-AMP renders mtDNA susceptible to damage in APTX deficient cells

por Akbari, Mansour, Sykora, Peter, Bohr, Vilhelm A.
Publicado 2015

The Impact of Base Excision DNA Repair in Age-Related Neurodegenerative Diseases

por Leandro, Giovana S., Sykora, Peter, Bohr, Vilhelm A.
Publicado 2015

Human exonuclease 1 (EXO1) activity characterization and its function on flap structures

por Keijzers, Guido, Bohr, Vilhelm A., Rasmussen, Lene Juel
Publicado 2015

Mitochondria in the signaling pathways that control longevity and health span

por Akbari, Mansour, Kirkwood, Thomas B.L., Bohr, Vilhelm A.
Publicado 2019

WRNing for the right DNA repair pathway choice

por Lee, Jong-Hyuk, Croteau, Deborah L., Bohr, Vilhelm A.
Publicado 2022

Metabolism, Genomics, and DNA Repair in the Mouse Aging Liver

por Lebel, Michel, de Souza-Pinto, Nadja C., Bohr, Vilhelm A.
Publicado 2011

Alteration of mitochondrial homeostasis is an early event in a C. elegans model of human tauopathy

por Palikaras, Konstantinos, Achanta, Kavya, Choi, Seoyun, Akbari, Mansour, Bohr, Vilhelm A.
Publicado 2021

Cytosolic Self-DNA—A Potential Source of Chronic Inflammation in Aging

por Akbari, Mansour, Shanley, Daryl P., Bohr, Vilhelm A., Rasmussen, Lene Juel
Publicado 2021

Mechanism of Werner DNA Helicase: POT1 and RPA Stimulates WRN to Unwind beyond Gaps in the Translocating Strand

por Ahn, Byungchan, Lee, Jae Wan, Jung, Hana, Beck, Gad, Bohr, Vilhelm A.
Publicado 2009

DNA binding residues in the RQC domain of Werner protein are critical for its catalytic activities

por Tadokoro, Takashi, Kulikowicz, Tomasz, Dawut, Lale, Croteau, Deborah L., Bohr, Vilhelm A.
Publicado 2012

Recent Advances in Understanding Werner Syndrome

por Shamanna, Raghavendra A., Croteau, Deborah L., Lee, Jong-Hyuk, Bohr, Vilhelm A.
Publicado 2017

Heterochromatin: an epigenetic point of view in aging

por Lee, Jong-Hyuk, Kim, Edward W., Croteau, Deborah L., Bohr, Vilhelm A.
Publicado 2020

Longevity and resistance to stress correlate with DNA repair capacity in Caenorhabditis elegans

por Hyun, Moonjung, Lee, Jihyun, Lee, Kyungjin, May, Alfred, Bohr, Vilhelm A., Ahn, Byungchan
Publicado 2008

Cooperation of DNA-PKcs and WRN helicase in the maintenance of telomeric D-loops

por Kusumoto-Matsuo, Rika, Opresko, Patricia L., Ramsden, Dale, Tahara, Hidetoshi, Bohr, Vilhelm A.
Publicado 2010

Human Cockayne syndrome B protein reciprocally communicates with mitochondrial proteins and promotes transcriptional elongation

por Berquist, Brian R., Canugovi, Chandrika, Sykora, Peter, Wilson, David M., Bohr, Vilhelm A.
Publicado 2012

The DNA structure and sequence preferences of WRN underlie its function in telomeric recombination events

por Edwards, Deanna N., Machwe, Amrita, Chen, Li, Bohr, Vilhelm A., Orren, David K.
Publicado 2015

Oxidative damage in telomeric DNA disrupts recognition by TRF1 and TRF2

por Opresko, Patricia L., Fan, Jinshui, Danzy, Shamika, Wilson, David M., Bohr, Vilhelm A.
Publicado 2005

Acetylation Regulates WRN Catalytic Activities and Affects Base Excision DNA Repair

por Muftuoglu, Meltem, Kusumoto, Rika, Speina, Elzbieta, Beck, Gad, Cheng, Wen-Hsing, Bohr, Vilhelm A.
Publicado 2008