Diet-Induced Obesity Impairs Outcomes and Induces Multi-Factorial Deficiencies in Effector T Cell Responses Following Anti-CTLA-4 Combinatorial Immunotherapy in Renal Tumor-Bearing...

por Turbitt, William J., Boi, Shannon K., Gibson, Justin T., Orlandella, Rachael M., Norian, Lyse A.
Publicado 2021

Obesity Does Not Exacerbate the Protumorigenic Systemic Environment in Sarcoma Subjects

por Buchta, Claire M., Boi, Shannon K., Miller, Benjamin J., Milhem, Mohammed M., Norian, Lyse A.
Publicado 2017

The Antidiabetic Agent Acarbose Improves Anti-PD-1 and Rapamycin Efficacy in Preclinical Renal Cancer

por Orlandella, Rachael M., Turbitt, William J., Gibson, Justin T., Boi, Shannon K., Li, Peng, Smith, Daniel L., Norian, Lyse A.
Publicado 2020

CD19-CAR T cells undergo exhaustion DNA methylation programming in patients with acute lymphoblastic leukemia

por Zebley, Caitlin C., Brown, Charmaine, Mi, Tian, Fan, Yiping, Alli, Shanta, Boi, Shannon, Galletti, Giovanni, Lugli, Enrico, Langfitt, Deanna, Metais, Jean-Yves, Lockey, Timothy, Meagher, Michael, Triplett, Brandon, Talleur, Aimee C., Gottschalk, Stephen, Youngblood, Ben
Publicado 2021

Obesity induces limited changes to systemic and local immune profiles in treatment-naive human clear cell renal cell carcinoma

por Gibson, Justin T., Norris, Katlyn E., Wald, Gal, Buchta Rosean, Claire M., Thomas, Lewis J., Boi, Shannon K., Bertrand, Laura A., Bing, Megan, Gordetsky, Jennifer B., Deshane, Jessy, Li, Peng, Brown, James A., Nepple, Kenneth G., Norian, Lyse A.
Publicado 2020

Beta cell-specific CD8(+) T cells maintain stem-cell memory-associated epigenetic programs during type 1 diabetes

por Abdelsamed, Hossam A., Zebley, Caitlin C., Nguyen, Hai, Rutishauser, Rachel L., Fan, Yiping, Ghoneim, Hazem E., Crawford, Jeremy Chase, Alfei, Francesca, Alli, Shanta, Ribeiro, Susan Pereira, Castellaw, Ashley H., McGargill, Maureen A., Jin, Hongjian, Boi, Shannon K., Speake, Cate, Serti, Elisavet, Turka, Laurence A., Busch, Michael E., Stone, Mars, Deeks, Steven G., Sekaly, Rafick-Pierre, Zehn, Dietmar, James, Eddie A., Nepom, Gerald T., Youngblood, Ben
Publicado 2020

Two subsets of stem-like CD8(+) memory T cell progenitors with distinct fate commitments in humans

por Galletti, Giovanni, De Simone, Gabriele, Mazza, Emilia M.C., Puccio, Simone, Mezzanotte, Claudia, Bi, Timothy M., Davydov, Alexey N., Metsger, Maria, Scamardella, Eloise, Alvisi, Giorgia, De Paoli, Federica, Zanon, Veronica, Scarpa, Alice, Camisa, Barbara, Colombo, Federico S., Anselmo, Achille, Peano, Clelia, Polletti, Sara, Mavilio, Domenico, Gattinoni, Luca, Boi, Shannon K., Youngblood, Benjamin A., Jones, Rhiannon E., Baird, Duncan M., Gostick, Emma, Llewellyn-Lacey, Sian, Ladell, Kristin, Price, David A., Chudakov, Dmitriy M., Newell, Evan W., Casucci, Monica, Lugli, Enrico
Publicado 2020

Obesity diminishes response to PD-1-based immunotherapies in renal cancer

por Boi, Shannon K, Orlandella, Rachael M, Gibson, Justin Tyler, Turbitt, William James, Wald, Gal, Thomas, Lewis, Buchta Rosean, Claire, Norris, Katlyn E, Bing, Megan, Bertrand, Laura, Gross, Brett P, Makkouk, Amani, Starenki, Dmytro, Farag, Kristine I, Sorge, Robert E, Brown, James A, Gordetsky, Jennifer, Yasin, Hesham, Garje, Rohan, Nandagopal, Lakshminarayanan, Weiner, George J, Lubaroff, David M, Arend, Rebecca C, Li, Peng, Zakharia, Yousef, Yang, Eddy, Salem, Aliasger K, Nepple, Kenneth, Marquez-Lago, Tatiana T, Norian, Lyse A
Publicado 2020