Single‐dose Pharmacokinetics of Eluxadoline in Healthy Participants With Normal Renal Function and Participants With Renal Impairment

por Boinpally, Ramesh, Weissman, Darren
Publicado 2022

Single‐Dose Pharmacokinetics and Safety of Ubrogepant in Adults With Hepatic Impairment: Results From an Open‐Label, Phase 1 Trial

por Boinpally, Ramesh, Lu, Kaifeng
Publicado 2022

Evaluation of the Pharmacokinetic Interaction and Safety of Atogepant Co-Administered with Acetaminophen or Naproxen in Healthy Participants: A Randomized Trial

por Boinpally, Ramesh, Spaventa, John, Chen, Kayla, Butler, Matthew
Publicado 2021

An Open‐Label Study to Evaluate the Effect of Eluxadoline on the Single‐Dose Pharmacokinetics of Midazolam in Healthy Participants

por Boinpally, Ramesh, McGeeney, Danielle, Kaczynski, Edward, Weissman, Darren
Publicado 2022

Single‐Dose Pharmacokinetics and Safety of Atogepant in Adults With Hepatic Impairment: Results From an Open‐Label, Phase 1 Trial

por Boinpally, Ramesh, Jakate, Abhijeet, Butler, Matthew, Borbridge, Lisa, Periclou, Antonia
Publicado 2021

Single Therapeutic and Supratherapeutic Doses of Ubrogepant Do Not Affect Cardiac Repolarization in Healthy Adults: Results From a Randomized Trial

por Jakate, Abhijeet, Boinpally, Ramesh, Butler, Matthew, Lu, Kaifeng, McGeeney, Danielle, Periclou, Antonia
Publicado 2019

Evaluation of the Pharmacokinetic Interaction of Ubrogepant Coadministered With Sumatriptan and of the Safety of Ubrogepant With Triptans

por Jakate, Abhijeet, Boinpally, Ramesh, Butler, Matthew, Lu, Kaifeng, McGeeney, Danielle, Periclou, Antonia
Publicado 2020

A Novel Once-Daily Fixed-Dose Combination of Memantine Extended Release and Donepezil for the Treatment of Moderate to Severe Alzheimer’s Disease: Two Phase I Studies in Healthy Vo...

por Boinpally, Ramesh, Chen, Laishun, Zukin, Stephen R., McClure, Natalie, Hofbauer, Robert K., Periclou, Antonia
Publicado 2015

A randomized, multicenter trial assessing the effects of rapastinel compared to ketamine, alprazolam, and placebo on simulated driving performance

por Su, Shengfang, Kay, Gary, Hochadel, Thomas, Rojo, Jonathan, Christopher Stein, J., Boinpally, Ramesh, Periclou, Antonia
Publicado 2021

A Single Supratherapeutic Dose of Atogepant Does Not Affect Cardiac Repolarization in Healthy Adults: Results From a Randomized, Single‐Dose, Phase 1 Crossover Trial

por Boinpally, Ramesh, McNamee, Brian, Yao, Li, Butler, Matthew, McGeeney, Danielle, Borbridge, Lisa, Periclou, Antonia
Publicado 2021

Atogepant Has No Clinically Relevant Effects on the Pharmacokinetics of an Ethinyl Estradiol/Levonorgestrel Oral Contraceptive in Healthy Female Participants

por Ankrom, Wendy, Xu, Jialin, Vallee, Marie‐Helene, Dockendorf, Marissa F., Armas, Danielle, Boinpally, Ramesh, Min, K. Chris
Publicado 2020

Linaclotide Reduced Response Time for Irritable Bowel Syndrome With Constipation Symptoms: Analysis of 4 Randomized Controlled Trials

por Brenner, Darren M., Lacy, Brian E., Ford, Alexander C., Bartolini, Wilmin, Wu, James, Shea, Elizabeth P., Bochenek, Wieslaw, Boinpally, Ramesh, Almansa, Cristina
Publicado 2023

Randomized Trial of 2 Delayed-Release Formulations of Linaclotide in Patients With Irritable Bowel Syndrome With Constipation

por Chey, William D., Sayuk, Gregory S., Bartolini, Wilmin, Reasner, David S., Fox, Susan M., Bochenek, Wieslaw, Boinpally, Ramesh, Shea, Elizabeth, Tripp, Kenneth, Borgstein, Niels
Publicado 2021

Pharmacokinetics and safety of ubrogepant when coadministered with calcitonin gene‒related peptide‐targeted monoclonal antibody migraine preventives in participants with migraine:...

por Jakate, Abhijeet, Blumenfeld, Andrew M., Boinpally, Ramesh, Butler, Matthew, Borbridge, Lisa, Contreras‐De Lama, Janette, McGeeney, Danielle, Periclou, Antonia, Lipton, Richard B.
Publicado 2021

A phase I study of OSI-461 in combination with mitoxantrone in patients with advanced solid tumors potentially responsive to mitoxantrone

por Resta, Lee P., Pili, Roberto, Eisenberger, Mario A., Spitz, Avery, King, Serina, Porter, Jennifer, Franke, Amy, Boinpally, Ramesh, Carducci, Michael A., Sweeney, Christopher J.
Publicado 2010

Atogepant Is Not Associated With Clinically Meaningful Alanine Aminotransferase Elevations in Healthy Adults

por Min, K. Chris, Kraft, Walter K., Bondiskey, Phung, Colón‐González, Francheska, Liu, Wen, Xu, Jialin, Panebianco, Deborah, Mixson, Lori, Dockendorf, Marissa F., Matthews, Catherine Z., Boinpally, Ramesh
Publicado 2020