The amyloid-beta forming tripeptide cleavage mechanism of γ-secretase

por Bolduc, David M, Montagna, Daniel R, Seghers, Matthew C, Wolfe, Michael S, Selkoe, Dennis J
Publicado 2016

Structural basis of nSH2 regulation and lipid binding in PI3Kα

por Miller, Michelle S., Schmidt-Kittler, Oleg, Bolduc, David M., Brower, Evan T., Chaves-Moreira, Daniele, Allaire, Marc, Kinzler, Kenneth W., Jennings, Ian G., Thompson, Philip E., Cole, Philip A., Amzel, L. Mario, Vogelstein, Bert, Gabelli, Sandra B.
Publicado 2014

Covalent ERα Antagonist H3B-6545 Demonstrates Encouraging Preclinical Activity in Therapy-Resistant Breast Cancer

por Furman, Craig, Puyang, Xiaoling, Zhang, Zhaojie, Wu, Zhenhua J., Banka, Deepti, Aithal, Kiran B., Albacker, Lee A., Hao, Ming-Hong, Irwin, Sean, Kim, Amy, Montesion, Meagan, Moriarty, Alyssa D., Murugesan, Karthikeyan, Nguyen, Tuong-Vi, Rimkunas, Victoria, Sahmoud, Tarek, Wick, Michael J., Yao, Shihua, Zhang, Xun, Zeng, Hao, Vaillancourt, Frédéric H., Bolduc, David M., Larsen, Nicholas, Zheng, Guo Zhu, Prajapati, Sudeep, Zhu, Ping, Korpal, Manav
Publicado 2022