Immune repertoire fingerprinting by principal component analysis reveals shared features in subject groups with common exposures

por Sevy, Alexander M., Soto, Cinque, Bombardi, Robin G., Meiler, Jens, Crowe, James E.
Publicado 2019

Diverse patterns of antibody variable gene repertoire disruption in patients with amyloid light chain (AL) amyloidosis

por Chen, Elaine C., Rubinstein, Samuel, Soto, Cinque, Bombardi, Robin G., Day, Samuel B., Myers, Luke, Zaytsev, Alexey, Majedi, Mahsa, Cornell, R. Frank, Crowe, James E.
Publicado 2020

Human antibody recognition of H7N9 influenza virus HA following natural infection

por Gilchuk, Iuliia M., Bangaru, Sandhya, Kose, Nurgun, Bombardi, Robin G., Trivette, Andrew, Li, Sheng, Turner, Hannah L., Carnahan, Robert H., Ward, Andrew B., Crowe, James E.
Publicado 2021

Human monoclonal antibodies against Ross River virus target epitopes within the E2 protein and protect against disease

por Powell, Laura A., Fox, Julie M., Kose, Nurgun, Kim, Arthur S., Majedi, Mahsa, Bombardi, Robin, Carnahan, Robert H., Slaughter, James C., Morrison, Thomas E., Diamond, Michael S., Crowe, James. E.
Publicado 2020

High Frequency of Shared Clonotypes in Human T Cell Receptor Repertoires

por Soto, Cinque, Bombardi, Robin G., Kozhevnikov, Morgan, Sinkovits, Robert S., Chen, Elaine C., Branchizio, Andre, Kose, Nurgun, Day, Samuel B., Pilkinton, Mark, Gujral, Madhusudan, Mallal, Simon, Crowe, James E.
Publicado 2020

Cross-reactive neutralizing human survivor monoclonal antibody BDBV223 targets the ebolavirus stalk

por King, Liam B., West, Brandyn R., Moyer, Crystal L., Gilchuk, Pavlo, Flyak, Andrew, Ilinykh, Philipp A., Bombardi, Robin, Hui, Sean, Huang, Kai, Bukreyev, Alexander, Crowe, James E., Saphire, Erica Ollmann
Publicado 2019

Mechanism of differential Zika and dengue virus neutralization by a public antibody lineage targeting the DIII lateral ridge

por Zhao, Haiyan, Xu, Lily, Bombardi, Robin, Nargi, Rachel, Deng, Zengqin, Errico, John M., Nelson, Christopher A., Dowd, Kimberly A., Pierson, Theodore C., Crowe, James E., Diamond, Michael S., Fremont, Daved H.
Publicado 2019

Human V(H)1-69 Gene-Encoded Human Monoclonal Antibodies against Staphylococcus aureus IsdB Use at Least Three Distinct Modes of Binding To Inhibit Bacterial Growth and Pathogenesis

por Bennett, Monique R., Dong, Jinhui, Bombardi, Robin G., Soto, Cinque, Parrington, Helen M., Nargi, Rachel S., Schoeder, Clara T., Nagel, Marcus B., Schey, Kevin L., Meiler, Jens, Skaar, Eric P., Crowe, James E.
Publicado 2019

Computational identification of HCV neutralizing antibodies with a common HCDR3 disulfide bond motif in the antibody repertoires of infected individuals

por Bozhanova, Nina G., Flyak, Andrew I., Brown, Benjamin P., Ruiz, Stormy E., Salas, Jordan, Rho, Semi, Bombardi, Robin G., Myers, Luke, Soto, Cinque, Bailey, Justin R., Crowe, James E., Bjorkman, Pamela J., Meiler, Jens
Publicado 2022

Antibodies targeting epitopes on the cell-surface form of NS1 protect against Zika virus infection during pregnancy

por Wessel, Alex W., Kose, Nurgun, Bombardi, Robin G., Roy, Vicky, Chantima, Warangkana, Mongkolsapaya, Juthathip, Edeling, Melissa A., Nelson, Christopher A., Bosch, Irene, Alter, Galit, Screaton, Gavin R., Fremont, David H., Crowe, James E., Diamond, Michael S.
Publicado 2020

Multi-Donor Longitudinal Antibody Repertoire Sequencing Reveals the Existence of Public Antibody Clonotypes in HIV-1 Infection

por Setliff, Ian, McDonnell, Wyatt J., Raju, Nagarajan, Bombardi, Robin G., Murji, Amyn A., Scheepers, Cathrine, Ziki, Rutendo, Mynhardt, Charissa, Shepherd, Bryan E., Mamchak, Alusha A., Garrett, Nigel, Karim, Salim Abdool, Mallal, Simon A., Crowe, James E., Morris, Lynn, Georgiev, Ivelin S.
Publicado 2018

Intramuscular Delivery of Replicon RNA Encoding ZIKV-117 Human Monoclonal Antibody Protects against Zika Virus Infection

por Erasmus, Jesse H., Archer, Jacob, Fuerte-Stone, Jasmine, Khandhar, Amit P., Voigt, Emily, Granger, Brian, Bombardi, Robin G., Govero, Jennifer, Tan, Qing, Durnell, Lorellin A., Coler, Rhea N., Diamond, Michael S., Crowe, James E., Reed, Steven G., Thackray, Larissa B., Carnahan, Robert H., Van Hoeven, Neal
Publicado 2020

Isolation of a Potently Neutralizing and Protective Human Monoclonal Antibody Targeting Yellow Fever Virus

por Doyle, Michael P., Genualdi, Joseph R., Bailey, Adam L., Kose, Nurgun, Gainza, Christopher, Rodriguez, Jessica, Reeder, Kristen M., Nelson, Christopher A., Jethva, Prashant N., Sutton, Rachel E., Bombardi, Robin G., Gross, Michael L., Julander, Justin G., Fremont, Daved H., Diamond, Michael S., Crowe, James E.
Publicado 2022

A multifunctional human monoclonal neutralizing antibody that targets a unique conserved epitope on influenza HA

por Bangaru, Sandhya, Zhang, Heng, Gilchuk, Iuliia M., Voss, Thomas G., Irving, Ryan P., Gilchuk, Pavlo, Matta, Pranathi, Zhu, Xueyong, Lang, Shanshan, Nieusma, Travis, Richt, Juergen A., Albrecht, Randy A., Vanderven, Hillary A., Bombardi, Robin, Kent, Stephen J., Ward, Andrew B., Wilson, Ian A., Crowe, James E.
Publicado 2018

Proteo-Genomic Analysis Identifies Two Major Sites of Vulnerability on Ebolavirus Glycoprotein for Neutralizing Antibodies in Convalescent Human Plasma

por Gilchuk, Pavlo, Guthals, Adrian, Bonissone, Stefano R., Shaw, Jared B., Ilinykh, Philipp A., Huang, Kai, Bombardi, Robin G., Liang, Jenny, Grinyo, Ariadna, Davidson, Edgar, Chen, Elaine C., Gunn, Bronwyn M., Alter, Galit, Saphire, Erica Ollmann, Doranz, Benjamin J., Bukreyev, Alexander, Zeitlin, Larry, Castellana, Natalie, Crowe, James E.
Publicado 2021

Cooperativity mediated by rationally selected combinations of human monoclonal antibodies targeting the henipavirus receptor binding protein

por Doyle, Michael P., Kose, Nurgun, Borisevich, Viktoriya, Binshtein, Elad, Amaya, Moushimi, Nagel, Marcus, Annand, Edward J., Armstrong, Erica, Bombardi, Robin, Dong, Jinhui, Schey, Kevin L., Broder, Christopher C., Zeitlin, Larry, Kuang, Erin A., Bornholdt, Zachary A., West, Brandyn R., Geisbert, Thomas W., Cross, Robert W., Crowe, James E.
Publicado 2021

Multifunctional Pan-ebolavirus Antibody Recognizes a Site of Broad Vulnerability on the Ebolavirus Glycoprotein

por Gilchuk, Pavlo, Kuzmina, Natalia, Ilinykh, Philipp A., Huang, Kai, Gunn, Bronwyn M., Bryan, Aubrey, Davidson, Edgar, Doranz, Benjamin J., Turner, Hannah L., Fusco, Marnie L., Bramble, Matthew S., Hoff, Nicole A., Binshtein, Elad, Kose, Nurgun, Flyak, Andrew I., Flinko, Robin, Orlandi, Chiara, Carnahan, Robert, Parrish, Erica H., Sevy, Alexander M., Bombardi, Robin G., Singh, Prashant K., Mukadi, Patrick, Muyembe-Tamfum, Jean Jacques, Ohi, Melanie D., Saphire, Erica Ollmann, Lewis, George K., Alter, Galit, Ward, Andrew B., Rimoin, Anne W., Bukreyev, Alexander, Crowe, James E.
Publicado 2018

Analysis of a Therapeutic Antibody Cocktail Reveals Determinants for Cooperative and Broad Ebolavirus Neutralization

por Gilchuk, Pavlo, Murin, Charles D., Milligan, Jacob C., Cross, Robert W., Mire, Chad E., Ilinykh, Philipp A., Huang, Kai, Kuzmina, Natalia, Altman, Pilar X., Hui, Sean, Gunn, Bronwyn M., Bryan, Aubrey L., Davidson, Edgar, Doranz, Benjamin J., Turner, Hannah L., Alkutkar, Tanwee, Flinko, Robin, Orlandi, Chiara, Carnahan, Robert, Nargi, Rachel, Bombardi, Robin G., Vodzak, Megan E., Li, Sheng, Okoli, Adaora, Ibeawuchi, Morris, Ohiaeri, Benjamin, Lewis, George K., Alter, Galit, Bukreyev, Alexander, Saphire, Erica Ollmann, Geisbert, Thomas W., Ward, Andrew B., Crowe, James E.
Publicado 2020

Integrated pipeline for the accelerated discovery of antiviral antibody therapeutics

por Gilchuk, Pavlo, Bombardi, Robin G., Erasmus, Jesse H., Tan, Qing, Nargi, Rachel, Soto, Cinque, Abbink, Peter, Suscovich, Todd J, Durnell, Lorellin A., Khandhar, Amit, Archer, Jacob, Liang, Jenny, Fouch, Mallorie E., Davidson, Edgar, Doranz, Benjamin J., Jones, Taylor, Larson, Elise, Ertel, Stacey, Granger, Brian, Fuerte-Stone, Jasmine, Roy, Vicky, Broge, Thomas, Linnekin, Thomas C., Linde, Caitlyn H., Gorman, Matthew J., Nkolola, Joseph, Alter, Galit, Reed, Steven G., Barouch, Dan H., Diamond, Michael S., Crowe, James E., Van Hoeven, Neal, Thackray, Larissa, Carnahan, Robert
Publicado 2020

Structural variant analysis of a cancer reference cell line sample using multiple sequencing technologies

por Talsania, Keyur, Shen, Tsai-wei, Chen, Xiongfong, Jaeger, Erich, Li, Zhipan, Chen, Zhong, Chen, Wanqiu, Tran, Bao, Kusko, Rebecca, Wang, Limin, Pang, Andy Wing Chun, Yang, Zhaowei, Choudhari, Sulbha, Colgan, Michael, Fang, Li Tai, Carroll, Andrew, Shetty, Jyoti, Kriga, Yuliya, German, Oksana, Smirnova, Tatyana, Liu, Tiantain, Li, Jing, Kellman, Ben, Hong, Karl, Hastie, Alex R., Natarajan, Aparna, Moshrefi, Ali, Granat, Anastasiya, Truong, Tiffany, Bombardi, Robin, Mankinen, Veronnica, Meerzaman, Daoud, Mason, Christopher E., Collins, Jack, Stahlberg, Eric, Xiao, Chunlin, Wang, Charles, Xiao, Wenming, Zhao, Yongmei
Publicado 2022