Protein Ubiquitylation in Pancreatic Cancer

por Bonacci, Thomas, Roignot, Julie, Soubeyran, Philippe
Publicado 2010

Alterations of host cell ubiquitination machinery by pathogenic bacteria

por Alomairi, Jaafar, Bonacci, Thomas, Ghigo, Eric, Soubeyran, Philippe
Publicado 2015

Oligomerization and Phosphorylation Dependent Regulation of ArgBP2 Adaptive Capabilities and Associated Functions

por Roignot, Julie, Bonacci, Thomas, Ghigo, Eric, Iovanna, Juan L., Soubeyran, Philippe
Publicado 2014

Redox-sensitive TP53INP1 SUMOylation as an oxidative stress sensor to activate TP53

por Bonacci, Thomas, Peuget, Sylvain, Soubeyran, Philippe, Iovanna, Juan, Dusetti, Nelson J
Publicado 2014

Regulation of NUB1 Activity through Non-Proteolytic Mdm2-Mediated Ubiquitination

por Bonacci, Thomas, Audebert, Stéphane, Camoin, Luc, Baudelet, Emilie, Iovanna, Juan-Lucio, Soubeyran, Philippe
Publicado 2017

FOXM1 Deubiquitination by USP21 Regulates Cell Cycle Progression and Paclitaxel Sensitivity in Basal-like Breast Cancer

por Arceci, Anthony, Bonacci, Thomas, Wang, Xianxi, Stewart, Kyle, Damrauer, Jeffrey S., Hoadley, Katherine A., Emanuele, Michael J.
Publicado 2019

Identification of a Drug Targeting an Intrinsically Disordered Protein Involved in Pancreatic Adenocarcinoma

por Neira, José L., Bintz, Jennifer, Arruebo, María, Rizzuti, Bruno, Bonacci, Thomas, Vega, Sonia, Lanas, Angel, Velázquez-Campoy, Adrián, Iovanna, Juan L., Abián, Olga
Publicado 2017

Proteomic Analysis Reveals a PLK1-Dependent G2/M Degradation Program and Links PKA-AKAP2 to Cell Cycle Control

por Mouery, Ryan D, Hsu, Carolyn, Bonacci, Thomas, Bolhuis, Derek L, Wang, Xianxi, Mills, Christine A, Toomer, E Drew, Canterbury, Owen G, Robertson, Kevin C, Branigan, Timothy B, Brown, Nicholas G, Herring, Laura E, Emanuele, Michael J
Publicado 2023

Functional conservation and divergence of the helix‐turn‐helix motif of E2 ubiquitin‐conjugating enzymes

por Welsh, Kaeli A, Bolhuis, Derek L, Nederstigt, Anneroos E, Boyer, Joshua, Temple, Brenda R S, Bonacci, Thomas, Gu, Li, Ordureau, Alban, Harper, J Wade, Steimel, Joshua P, Zhang, Qi, Emanuele, Michael J, Harrison, Joseph S, Brown, Nicholas G
Publicado 2021

Ubiquitin chain-elongating enzyme UBE2S activates the RING E3 ligase APC/C for substrate priming

por Martinez-Chacin, Raquel C., Bodrug, Tatyana, Bolhuis, Derek L., Kedziora, Katarzyna M., Bonacci, Thomas, Ordureau, Alban, Gibbs, Morgan E., Weissmann, Florian, Qiao, Renping, Grant, Gavin D., Cook, Jeanette G., Peters, Jan-Michael, Harper, J. Wade, Emanuele, Michael J., Brown, Nicholas G.
Publicado 2020

Self-oligomerization regulates stability of survival motor neuron protein isoforms by sequestering an SCF(Slmb) degron

por Gray, Kelsey M., Kaifer, Kevin A., Baillat, David, Wen, Ying, Bonacci, Thomas R., Ebert, Allison D., Raimer, Amanda C., Spring, Ashlyn M., Have, Sara ten, Glascock, Jacqueline J., Gupta, Kushol, Van Duyne, Gregory D., Emanuele, Michael J., Lamond, Angus I., Wagner, Eric J., Lorson, Christian L., Matera, A. Gregory
Publicado 2018

In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators

por Franks, Jennifer L., Martinez-Chacin, Raquel C., Wang, Xianxi, Tiedemann, Rochelle L., Bonacci, Thomas, Choudhury, Rajarshi, Bolhuis, Derek L., Enrico, Taylor P., Mouery, Ryan D., Damrauer, Jeffrey S., Yan, Feng, Harrison, Joseph S., Major, M. Ben, Hoadley, Katherine A., Suzuki, Aussie, Rothbart, Scott B., Brown, Nicholas G., Emanuele, Michael J.
Publicado 2020

Time-resolved cryo-EM (TR-EM) analysis of substrate polyubiquitination by the RING E3 anaphase-promoting complex/cyclosome (APC/C)

por Bodrug, Tatyana, Welsh, Kaeli A., Bolhuis, Derek L., Paulаkonis, Ethan, Martinez-Chacin, Raquel C., Liu, Bei, Pinkin, Nicholas, Bonacci, Thomas, Cui, Liying, Xu, Pengning, Roscow, Olivia, Amann, Sascha Josef, Grishkovskaya, Irina, Emanuele, Michael J., Harrison, Joseph S., Steimel, Joshua P., Hahn, Klaus M., Zhang, Wei, Zhong, Ellen D., Haselbach, David, Brown, Nicholas G.
Publicado 2023