Inhibition of ERK1/2 Restores GSK3β Activity and Protein Synthesis Levels in a Model of Tuberous Sclerosis

por Pal, Rituraj, Bondar, Vitaliy V., Adamski, Carolyn J., Rodney, George G., Sardiello, Marco
Publicado 2017

A kinome-wide RNAi screen identifies ERK2 as a druggable regulator of Shank3 stability

por Wang, Li, Adamski, Carolyn J., Bondar, Vitaliy V, Craigen, Evelyn, Collette, John R., Pang, Kaifang, Han, Kihoon, Liu, Zhandong, Sifers, Richard N., Holder, J. Lloyd, Zoghbi, Huda Y.
Publicado 2019

Understanding LRRK2 kinase activity in preclinical models and human subjects through quantitative analysis of LRRK2 and pT73 Rab10

por Wang, Xiang, Negrou, Elvira, Maloney, Michael T., Bondar, Vitaliy V., Andrews, Shan V., Montalban, Manuel, Llapashtica, Ceyda, Maciuca, Romeo, Nguyen, Hoang, Solanoy, Hilda, Arguello, Annie, Przybyla, Laralynne, Moerke, Nathan J., Huntwork-Rodriguez, Sarah, Henry, Anastasia G.
Publicado 2021

An autism-linked missense mutation in SHANK3 reveals the modularity of Shank3 function

por Wang, Li, Pang, Kaifang, Han, Kihoon, Adamski, Carolyn J., Wang, Wei, He, Lingjie, Lai, Jason K., Bondar, Vitaliy V, Duman, Joseph G., Richman, Ronald, Tolias, Kimberley F., Barth, Patrick, Palzkill, Timothy, Liu, Zhandong, Holder, J. Lloyd, Zoghbi, Huda Y.
Publicado 2019

Cross-species genetic screens identify transglutaminase 5 as a regulator of polyglutamine-expanded ataxin-1

por Lee, Won-Seok, Al-Ramahi, Ismael, Jeong, Hyun-Hwan, Jang, Youjin, Lin, Tao, Adamski, Carolyn J., Lavery, Laura A., Rath, Smruti, Richman, Ronald, Bondar, Vitaliy V., Alcala, Elizabeth, Revelli, Jean-Pierre, Orr, Harry T., Liu, Zhandong, Botas, Juan, Zoghbi, Huda Y.
Publicado 2022

mTORC1-independent TFEB activation via Akt inhibition promotes cellular clearance in neurodegenerative storage diseases

por Palmieri, Michela, Pal, Rituraj, Nelvagal, Hemanth R., Lotfi, Parisa, Stinnett, Gary R., Seymour, Michelle L., Chaudhury, Arindam, Bajaj, Lakshya, Bondar, Vitaliy V., Bremner, Laura, Saleem, Usama, Tse, Dennis Y., Sanagasetti, Deepthi, Wu, Samuel M., Neilson, Joel R., Pereira, Fred A., Pautler, Robia G., Rodney, George G., Cooper, Jonathan D., Sardiello, Marco
Publicado 2017

Corrigendum: mTORC1-independent TFEB activation via Akt inhibition promotes cellular clearance in neurodegenerative storage diseases

por Palmieri, Michela, Pal, Rituraj, Nelvagal, Hemanth R., Lotfi, Parisa, Stinnett, Gary R., Seymour, Michelle L., Chaudhury, Arindam, Bajaj, Lakshya, Bondar, Vitaliy V., Bremner, Laura, Saleem, Usama, Tse, Dennis Y., Sanagasetti, Deepthi, Wu, Samuel M., Neilson, Joel R., Pereira, Fred A., Pautler, Robia G., Rodney, George G., Cooper, Jonathan D., Sardiello, Marco
Publicado 2017