Activation of IGF1R/p110β/AKT/mTOR confers resistance to α-specific PI3K inhibition

por Leroy, Cedric, Ramos, Pedro, Cornille, Karen, Bonenfant, Debora, Fritsch, Christine, Voshol, Hans, Bentires-Alj, Mohamed
Publicado 2016

ANO1/TMEM16A interacts with EGFR and correlates with sensitivity to EGFR-targeting therapy in head and neck cancer

por Bill, Anke, Gutierrez, Abraham, Kulkarni, Sucheta, Kemp, Carolyn, Bonenfant, Debora, Voshol, Hans, Duvvuri, Umamaheswar, Gaither, L. Alex
Publicado 2015

Oncogenic Signalling of PEAK2 Pseudokinase in Colon Cancer

por Lecointre, Céline, Fourgous, Elise, Montarras, Ingrid, Kerneur, Clément, Simon, Valérie, Boublik, Yvan, Bonenfant, Débora, Robert, Bruno, Martineau, Pierre, Roche, Serge
Publicado 2022

Protein Tyrosine Phosphatase SHP2 Controls Interleukin-8 Expression in Breast Cancer Cells

por Amante, Romain J., Auf der Maur, Priska, Richina, Veronica, Sethi, Atul, Iesmantavicius, Vytautas, Bonenfant, Debora, Aceto, Nicola, Bentires-Alj, Mohamed
Publicado 2022

Genome-wide CRISPR screening reveals genetic modifiers of mutant EGFR dependence in human NSCLC

por Zeng, Hao, Castillo-Cabrera, Johnny, Manser, Mika, Lu, Bo, Yang, Zinger, Strande, Vaik, Begue, Damien, Zamponi, Raffaella, Qiu, Shumei, Sigoillot, Frederic, Wang, Qiong, Lindeman, Alicia, Reece-Hoyes, John S, Russ, Carsten, Bonenfant, Debora, Jiang, Xiaomo, Wang, Youzhen, Cong, Feng
Publicado 2019

Inhibition of DDR1‐BCR signalling by nilotinib as a new therapeutic strategy for metastatic colorectal cancer

por Jeitany, Maya, Leroy, Cédric, Tosti, Priscillia, Lafitte, Marie, Le Guet, Jordy, Simon, Valérie, Bonenfant, Debora, Robert, Bruno, Grillet, Fanny, Mollevi, Caroline, El Messaoudi, Safia, Otandault, Amaëlle, Canterel‐Thouennon, Lucile, Busson, Muriel, Thierry, Alain R, Martineau, Pierre, Pannequin, Julie, Roche, Serge, Sirvent, Audrey
Publicado 2018

BRD9 degraders as chemosensitizers in acute leukemia and multiple myeloma

por Weisberg, Ellen, Chowdhury, Basudev, Meng, Chengcheng, Case, Abigail E., Ni, Wei, Garg, Swati, Sattler, Martin, Azab, Abdel Kareem, Sun, Jennifer, Muz, Barbara, Sanchez, Dana, Toure, Anthia, Stone, Richard M., Galinsky, Ilene, Winer, Eric, Gleim, Scott, Gkountela, Sofia, Kedves, Alexia, Harrington, Edmund, Abrams, Tinya, Zoller, Thomas, Vaupel, Andrea, Manley, Paul, Faller, Michael, Chung, BoYee, Chen, Xin, Busenhart, Philipp, Stephan, Christine, Calkins, Keith, Bonenfant, Debora, Thoma, Claudio R., Forrester, William, Griffin, James D.
Publicado 2022