Preservation of muscle mass as a strategy to reduce the toxic effects of cancer chemotherapy on body composition

por Pin, Fabrizio, Couch, Marion E., Bonetto, Andrea
Publicado 2018

The Mitochondria-Targeting Agent MitoQ Improves Muscle Atrophy, Weakness and Oxidative Metabolism in C26 Tumor-Bearing Mice

por Pin, Fabrizio, Huot, Joshua R., Bonetto, Andrea
Publicado 2022

PGC1α overexpression preserves muscle mass and function in cisplatin‐induced cachexia

por Huot, Joshua R., Pin, Fabrizio, Chatterjee, Rohit, Bonetto, Andrea
Publicado 2022

Molecular Mechanisms Responsible for the Rescue Effects of Pamidronate on Muscle Atrophy in Pediatric Burn Patients

por Pin, Fabrizio, Bonetto, Andrea, Bonewald, Lynda F., Klein, Gordon L.
Publicado 2019

HCT116 colorectal liver metastases exacerbate muscle wasting in a mouse model for the study of colorectal cancer cachexia

por Huot, Joshua R., Novinger, Leah J., Pin, Fabrizio, Bonetto, Andrea
Publicado 2020

MC38 Tumors Induce Musculoskeletal Defects in Colorectal Cancer

por Huot, Joshua R., Pin, Fabrizio, Essex, Alyson L., Bonetto, Andrea
Publicado 2021

Targeting the Activin Receptor Signaling to Counteract the Multi-Systemic Complications of Cancer and Its Treatments

por Hulmi, Juha J., Nissinen, Tuuli A., Penna, Fabio, Bonetto, Andrea
Publicado 2021

Treatment with Soluble Activin Receptor Type IIB Alters Metabolic Response in Chemotherapy-Induced Cachexia

por O’Connell, Thomas M., Pin, Fabrizio, Couch, Marion E., Bonetto, Andrea
Publicado 2019

Cachexia induced by cancer and chemotherapy yield distinct perturbations to energy metabolism

por Pin, Fabrizio, Barreto, Rafael, Couch, Marion E., Bonetto, Andrea, O'Connell, Thomas M.
Publicado 2019

Cancer and Chemotherapy Contribute to Muscle Loss by Activating Common Signaling Pathways

por Barreto, Rafael, Mandili, Giorgia, Witzmann, Frank A., Novelli, Francesco, Zimmers, Teresa A., Bonetto, Andrea
Publicado 2016

Chemotherapy-related cachexia is associated with mitochondrial depletion and the activation of ERK1/2 and p38 MAPKs

por Barreto, Rafael, Waning, David L., Gao, Hongyu, Liu, Yunlong, Zimmers, Teresa A., Bonetto, Andrea
Publicado 2016

Effect of the specific proteasome inhibitor bortezomib on cancer‐related muscle wasting

por Penna, Fabio, Bonetto, Andrea, Aversa, Zaira, Minero, Valerio Giacomo, Rossi Fanelli, Filippo, Costelli, Paola, Muscaritoli, Maurizio
Publicado 2015

Bisphosphonate Treatment Ameliorates Chemotherapy-Induced Bone and Muscle Abnormalities in Young Mice

por Essex, Alyson L., Pin, Fabrizio, Huot, Joshua R., Bonewald, Lynda F., Plotkin, Lilian I., Bonetto, Andrea
Publicado 2019

STAT3 Activation in Skeletal Muscle Links Muscle Wasting and the Acute Phase Response in Cancer Cachexia

por Bonetto, Andrea, Aydogdu, Tufan, Kunzevitzky, Noelia, Guttridge, Denis C., Khuri, Sawsan, Koniaris, Leonidas G., Zimmers, Teresa A.
Publicado 2011

Transcriptome Profiling Reveals Matrisome Alteration as a Key Feature of Ovarian Cancer Progression

por Mitra, Sumegha, Tiwari, Kartikeya, Podicheti, Ram, Pandhiri, Taruni, Rusch, Douglas B., Bonetto, Andrea, Zhang, Chi, Mitra, Anirban K.
Publicado 2019

miR21 deletion in osteocytes has direct and indirect effects on skeletal muscle in a sex-dimorphic manner in mice

por Essex, Alyson L., Deosthale, Padmini, Huot, Joshua R., Davis, Hannah M., Momeni, Nicholas, Bonetto, Andrea, Plotkin, Lilian I.
Publicado 2022

ACVR2B antagonism as a countermeasure to multi‐organ perturbations in metastatic colorectal cancer cachexia

por Huot, Joshua R., Pin, Fabrizio, Narasimhan, Ashok, Novinger, Leah J., Keith, Austin S., Zimmers, Teresa A., Willis, Monte S., Bonetto, Andrea
Publicado 2020

Metabolic Biomarkers for the Early Detection of Cancer Cachexia

por O’Connell, Thomas M., Golzarri-Arroyo, Lilian, Pin, Fabrizio, Barreto, Rafael, Dickinson, Stephanie L., Couch, Marion E., Bonetto, Andrea
Publicado 2021

Chronic Treatment with Multi-Kinase Inhibitors Causes Differential Toxicities on Skeletal and Cardiac Muscles

por Huot, Joshua R., Essex, Alyson L., Gutierrez, Maya, Barreto, Rafael, Wang, Meijing, Waning, David L., Plotkin, Lilian I., Bonetto, Andrea
Publicado 2019

Growth of ovarian cancer xenografts causes loss of muscle and bone mass: a new model for the study of cancer cachexia

por Pin, Fabrizio, Barreto, Rafael, Kitase, Yukiko, Mitra, Sumegha, Erne, Carlie E., Novinger, Leah J., Zimmers, Teresa A., Couch, Marion E., Bonewald, Lynda F., Bonetto, Andrea
Publicado 2018