Enhancement of Antiviral T-Cell Responses by Vitamin C Suggests New Strategies to Improve Manufacturing of Virus-Specific T Cells for Adoptive Immunotherapy

por Laubert, Miriam, Bonifacius, Agnes, Dragon, Anna Christina, Mangare, Caroline, Blasczyk, Rainer, Huehn, Jochen, Eiz-Vesper, Britta
Publicado 2022

Yersinia Pseudotuberculosis Modulates Regulatory T Cell Stability via Injection of Yersinia Outer Proteins in a Type III Secretion System-Dependent Manner

por Elfiky, Ahmed, Bonifacius, Agnes, Pezoldt, Joern, Pasztoi, Maria, Chaoprasid, Paweena, Sadana, Pooja, El-Sherbeeny, Nagla, Hagras, Magda, Scrima, Andrea, Dersch, Petra, Huehn, Jochen
Publicado 2018

Reinforcement of cell-mediated immunity driven by tumor-associated Epstein-Barr virus (EBV)-specific T cells during targeted B-cell therapy with rituximab

por Tischer-Zimmermann, Sabine, Bonifacius, Agnes, Santamorena, Maria Michela, Mausberg, Philip, Stoll, Sven, Döring, Marius, Kalinke, Ulrich, Blasczyk, Rainer, Maecker-Kolhoff, Britta, Eiz-Vesper, Britta
Publicado 2023

Yersinia pseudotuberculosis supports Th17 differentiation and limits de novo regulatory T cell induction by directly interfering with T cell receptor signaling

por Pasztoi, Maria, Bonifacius, Agnes, Pezoldt, Joern, Kulkarni, Devesha, Niemz, Jana, Yang, Juhao, Teich, René, Hajek, Janina, Pisano, Fabio, Rohde, Manfred, Dersch, Petra, Huehn, Jochen
Publicado 2017

Long-Lasting Immunity Against SARS-CoV-2: Dream or Reality?

por Gussarow, Daniel, Bonifacius, Agnes, Cossmann, Anne, Stankov, Metodi V., Mausberg, Philip, Tischer-Zimmermann, Sabine, Gödecke, Nina, Kalinke, Ulrich, Behrens, Georg M. N., Blasczyk, Rainer, Eiz-Vesper, Britta
Publicado 2021

Staphylococcus aureus Alpha-Toxin Limits Type 1 While Fostering Type 3 Immune Responses

por Bonifacius, Agnes, Goldmann, Oliver, Floess, Stefan, Holtfreter, Silva, Robert, Philippe A., Nordengrün, Maria, Kruse, Friederike, Lochner, Matthias, Falk, Christine S., Schmitz, Ingo, Bröker, Barbara M., Medina, Eva, Huehn, Jochen
Publicado 2020

Adoptive Allogeneic T-Cell Therapy Improves the Clinical Outcome of JC Virus Granule Cell Neuronopathy: A Case Report

por Grote-Levi, Lea, Möhn, Nora, Bonifacius, Agnes, Tischer-Zimmermann, Sabine, Schweitzer, Finja, Mahmoudi, Nima, Silling, Steffi, Warnke, Clemens, Maecker-Kolhoff, Britta, Wattjes, Mike P., Eiz-Vesper, Britta, Höglinger, Günter U., Skripuletz, Thomas
Publicado 2023

Antiviral T-Cell Frequencies in a Healthy Population: Reference Values for Evaluating Antiviral Immune Cell Profiles in Immunocompromised Patients

por Schulze Lammers, Friederike C., Bonifacius, Agnes, Tischer-Zimmermann, Sabine, Goudeva, Lilia, Martens, Jörg, Lepenies, Bernd, von Karpowitz, Maria, Einecke, Gunilla, Beutel, Gernot, Skripuletz, Thomas, Blasczyk, Rainer, Beier, Rita, Maecker-Kolhoff, Britta, Eiz-Vesper, Britta
Publicado 2022

Severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) specific cellular and humoral immunity in Corovavirus Disease-2019 (COVID-19) convalescence after liver transplant...

por Kirchner, Theresa, Sauer, Hagen, Heinrich, Sophia, Bonifacius, Agnes, Louisa, Ruhl, Pink, Isabell, Engel, Bastian, Saunders, Emily, Martens, Joerg, Hoeper, Marius M., Blasczkyk, Rainer, Wedemeyer, Heiner, Jaeckel, Elmar, Falk, Christine, Eiz-Vesper, Britta, Taubert, Richard
Publicado 2022

Reduced humoral but stable cellular SARS-CoV-2-specific immunity in liver transplant recipients in the first year after COVID-19

por Kirchner, Theresa, Heinrich, Sophia, Bonifacius, Agnes, Engel, Bastian, Ruhl, Louisa, Pink, Isabell, Thomas, Nele, Martens, Joerg, Hoeper, Marius M., Blasczyk, Rainer, Wedemeyer, Heiner, Jaeckel, Elmar, Li, Yang, Falk, Christine S., Eiz-Vesper, Britta, Taubert, Richard
Publicado 2022

Evaluating Saliva Sampling with Reverse Transcription Loop-mediated Isothermal Amplification to Improve Access to SARS-CoV-2 Diagnosis in Low-Resource Settings

por Suwarti, Suwarti, Zanjabila, Sabighoh, Bonifacius, Da Costa, Yacobus, Bogh, Claus, Subekti, Decy, Jeny, Jeny, Dewi, Ayu Madri, Nuraeni, Nunung, Rahardjani, Mutia, Elyazar, Iqbal, Nelwan, Erni J., Shankar, Anuraj H, Baird, J. Kevin, Hamers, Raph L.
Publicado 2022

CAR-T cells and TRUCKs that recognize an EBNA-3C-derived epitope presented on HLA-B*35 control Epstein-Barr virus-associated lymphoproliferation

por Dragon, Anna Christina, Zimmermann, Katharina, Nerreter, Thomas, Sandfort, Deborah, Lahrberg, Julia, Klöß, Stephan, Kloth, Christina, Mangare, Caroline, Bonifacius, Agnes, Tischer-Zimmermann, Sabine, Blasczyk, Rainer, Maecker-Kolhoff, Britta, Uchanska-Ziegler, Barbara, Abken, Hinrich, Schambach, Axel, Hudecek, Michael, Eiz-Vesper, Britta
Publicado 2020

CAR-Ts redirected against the Thomsen-Friedenreich antigen CD176 mediate specific elimination of malignant cells from leukemia and solid tumors

por Dragon, Anna Christina, Beermann, Luca Marie, Umland, Melina, Bonifacius, Agnes, Malinconico, Chiara, Ruhl, Louisa, Kehler, Patrik, Gellert, Johanna, Weiß, Lisa, Mayer-Hain, Sarah, Zimmermann, Katharina, Riese, Sebastian, Thol, Felicitas, Beutel, Gernot, Maecker-Kolhoff, Britta, Yamamoto, Fumiichiro, Blasczyk, Rainer, Schambach, Axel, Hust, Michael, Hudecek, Michael, Eiz-Vesper, Britta
Publicado 2023

Repertoire characterization and validation of gB-specific human IgGs directly cloned from humanized mice vaccinated with dendritic cells and protected against HCMV

por Theobald, Sebastian J., Kreer, Christoph, Khailaie, Sahamoddin, Bonifacius, Agnes, Eiz-Vesper, Britta, Figueiredo, Constanca, Mach, Michael, Backovic, Marija, Ballmaier, Matthias, Koenig, Johannes, Olbrich, Henning, Schneider, Andreas, Volk, Valery, Danisch, Simon, Gieselmann, Lutz, Ercanoglu, Meryem Seda, Messerle, Martin, von Kaisenberg, Constantin, Witte, Torsten, Klawonn, Frank, Meyer-Hermann, Michael, Klein, Florian, Stripecke, Renata
Publicado 2020

Correction: Repertoire characterization and validation of gB-specific human IgGs directly cloned from humanized mice vaccinated with dendritic cells and protected against HCMV

por Theobald, Sebastian J., Kreer, Christoph, Khailaie, Sahamoddin, Bonifacius, Agnes, Eiz-Vesper, Britta, Figueiredo, Constanca, Mach, Michael, Backovic, Marija, Ballmaier, Matthias, Koenig, Johannes, Olbrich, Henning, Schneider, Andreas, Volk, Valery, Danisch, Simon, Gieselmann, Lutz, Ercanoglu, Meryem Seda, Messerle, Martin, von Kaisenberg, Constantin, Witte, Torsten, Klawonn, Frank, Meyer-Hermann, Michael, Klein, Florian, Stripecke, Renata
Publicado 2021

Rapid Manufacturing of Highly Cytotoxic Clinical-Grade SARS-CoV-2-specific T Cell Products Covering SARS-CoV-2 and Its Variants for Adoptive T Cell Therapy

por Bonifacius, Agnes, Tischer-Zimmermann, Sabine, Santamorena, Maria Michela, Mausberg, Philip, Schenk, Josephine, Koch, Stephanie, Barnstorf-Brandes, Johanna, Gödecke, Nina, Martens, Jörg, Goudeva, Lilia, Verboom, Murielle, Wittig, Jana, Maecker-Kolhoff, Britta, Baurmann, Herrad, Clark, Caren, Brauns, Olaf, Simon, Martina, Lang, Peter, Cornely, Oliver A., Hallek, Michael, Blasczyk, Rainer, Seiferling, Dominic, Köhler, Philipp, Eiz-Vesper, Britta
Publicado 2022

COVID-19 immune signatures reveal stable antiviral T cell function despite declining humoral responses

por Bonifacius, Agnes, Tischer-Zimmermann, Sabine, Dragon, Anna C., Gussarow, Daniel, Vogel, Alexander, Krettek, Ulrike, Gödecke, Nina, Yilmaz, Mustafa, Kraft, Anke R.M., Hoeper, Marius M., Pink, Isabell, Schmidt, Julius J., Li, Yang, Welte, Tobias, Maecker-Kolhoff, Britta, Martens, Jörg, Berger, Marc Moritz, Lobenwein, Corinna, Stankov, Metodi V., Cornberg, Markus, David, Sascha, Behrens, Georg M.N., Witzke, Oliver, Blasczyk, Rainer, Eiz-Vesper, Britta
Publicado 2021

Induced dendritic cells co-expressing GM-CSF/IFN-α/tWT1 priming T and B cells and automated manufacturing to boost GvL

por Bialek-Waldmann, Julia K., Domning, Sabine, Esser, Ruth, Glienke, Wolfgang, Mertens, Mira, Aleksandrova, Krasimira, Arseniev, Lubomir, Kumar, Suresh, Schneider, Andreas, Koenig, Johannes, Theobald, Sebastian J., Tsay, Hsin-Chieh, Cornelius, Angela D.A., Bonifacius, Agnes, Eiz-Vesper, Britta, Figueiredo, Constanca, Schaudien, Dirk, Talbot, Steven R., Bleich, Andre, Spineli, Loukia M., von Kaisenberg, Constantin, Clark, Caren, Blasczyk, Rainer, Heuser, Michael, Ganser, Arnold, Köhl, Ulrike, Farzaneh, Farzin, Stripecke, Renata
Publicado 2021

Targeted proteomics identifies circulating biomarkers associated with active COVID-19 and post-COVID-19

por Zoodsma, Martijn, de Nooijer, Aline H., Grondman, Inge, Gupta, Manoj Kumar, Bonifacius, Agnes, Koeken, Valerie A. C. M., Kooistra, Emma, Kilic, Gizem, Bulut, Ozlem, Gödecke, Nina, Janssen, Nico, Kox, Matthijs, Domínguez-Andrés, Jorge, van Gammeren, Adriaan J., Ermens, Anton A. M., van der Ven, Andre J. A. M., Pickkers, Peter, Blasczyk, Rainer, Behrens, Georg M. N., van de Veerdonk, Frank L., Joosten, Leo A. B., Xu, Cheng-Jian, Eiz-Vesper, Britta, Netea, Mihai G., Li, Yang
Publicado 2022

Patient-tailored adoptive immunotherapy with EBV-specific T cells from related and unrelated donors

por Bonifacius, Agnes, Lamottke, Britta, Tischer-Zimmermann, Sabine, Schultze-Florey, Rebecca, Goudeva, Lilia, Heuft, Hans-Gert, Arseniev, Lubomir, Beier, Rita, Beutel, Gernot, Cario, Gunnar, Fröhlich, Birgit, Greil, Johann, Hansmann, Leo, Hasenkamp, Justin, Höfs, Michaela, Hundsdoerfer, Patrick, Jost, Edgar, Kafa, Kinan, Kriege, Oliver, Kröger, Nicolaus, Mathas, Stephan, Meisel, Roland, Nathrath, Michaela, Putkonen, Mervi, Ravens, Sarina, Reinhardt, Hans Christian, Sala, Elisa, Sauer, Martin G., Schmitt, Clemens, Schroers, Roland, Steckel, Nina Kristin, Trappe, Ralf Ulrich, Verbeek, Mareike, Wolff, Daniel, Blasczyk, Rainer, Eiz-Vesper, Britta, Maecker-Kolhoff, Britta
Publicado 2023