Structural and mechanistic basis of the EMC-dependent biogenesis of distinct transmembrane clients

por Miller-Vedam, Lakshmi E, Bräuning, Bastian, Popova, Katerina D, Schirle Oakdale, Nicole T, Bonnar, Jessica L, Prabu, Jesuraj R, Boydston, Elizabeth A, Sevillano, Natalia, Shurtleff, Matthew J, Stroud, Robert M, Craik, Charles S, Schulman, Brenda A, Frost, Adam, Weissman, Jonathan S
Publicado 2020

Mapping information-rich genotype-phenotype landscapes with genome-scale Perturb-seq

por Replogle, Joseph M., Saunders, Reuben A., Pogson, Angela N., Hussmann, Jeffrey A., Lenail, Alexander, Guna, Alina, Mascibroda, Lauren, Wagner, Eric J., Adelman, Karen, Lithwick-Yanai, Gila, Iremadze, Nika, Oberstrass, Florian, Lipson, Doron, Bonnar, Jessica L., Jost, Marco, Norman, Thomas M., Weissman, Jonathan S.
Publicado 2022

Maximizing CRISPRi efficacy and accessibility with dual-sgRNA libraries and optimal effectors

por Replogle, Joseph M, Bonnar, Jessica L, Pogson, Angela N, Liem, Christina R, Maier, Nolan K, Ding, Yufang, Russell, Baylee J, Wang, Xingren, Leng, Kun, Guna, Alina, Norman, Thomas M, Pak, Ryan A, Ramos, Daniel M, Ward, Michael E, Gilbert, Luke A, Kampmann, Martin, Weissman, Jonathan S, Jost, Marco
Publicado 2022