Cancer Cell B7-H3 Expression Is More Prevalent in the Pancreato-Biliary Subtype of Ampullary Cancer Than in Pancreatic Cancer

por Geerdes, Emma E., Sideras, Kostandinos, Aziz, M. Hosein, van Eijck, Casper H., Bruno, Marco J., Sprengers, Dave, Boor, Patrick P. C., Kwekkeboom, Jaap
Publicado 2021

Detection of oncogenic mutations in paired circulating tumor DNA and circulating tumor cells in patients with hepatocellular carcinoma

por Ge, Zhouhong, Helmijr, Jean C.A., Jansen, Maurice P.H.M., Boor, Patrick P.C., Noordam, Lisanne, Peppelenbosch, Maikel, Kwekkeboom, Jaap, Kraan, Jaco, Sprengers, Dave
Publicado 2021

Characterization of Antigen-Presenting Cell Subsets in Human Liver-Draining Lymph Nodes

por Boor, Patrick P. C., Bosma, Brenda M., Tran, Khe T. C., van der Laan, Luc J. W., Hagenaars, Hanneke, IJzermans, Jan N. M., Metselaar, Herold J., Kwekkeboom, Jaap
Publicado 2019

Current Tolerance-Associated Peripheral Blood Gene Expression Profiles After Liver Transplantation Are Influenced by Immunosuppressive Drugs and Prior Cytomegalovirus Infection

por Duizendstra, Aafke A., van der Grift, Michelle V., Boor, Patrick P., Noordam, Lisanne, de Knegt, Robert J., Peppelenbosch, Maikel P., Betjes, Michiel G. H., Litjens, Nicolle H. R., Kwekkeboom, Jaap
Publicado 2022

HHLA2 is expressed in pancreatic and ampullary cancers and increased expression is associated with better post-surgical prognosis

por Boor, Patrick P. C., Sideras, Kostandinos, Biermann, Katharina, Hosein Aziz, M., Levink, Iris J. M., Mancham, Shanta, Erler, Nicole S., Tang, Xudong, van Eijck, Casper H., Bruno, Marco J., Sprengers, Dave, Zang, Xingxing, Kwekkeboom, Jaap
Publicado 2020

Systemic T-cell and humoral responses against cancer testis antigens in hepatocellular carcinoma patients

por Noordam, Lisanne, de Beijer, Monique T.A., Mancham, Shanta, Vogler, Isabel, Boor, Patrick P.C., de Ruiter, Valeska, Luijten, Robbie, IJzermans, Jan N.M., Sahin, Ugur, Bruno, Marco J., Sprengers, Dave, Buschow, Sonja I., Kwekkeboom, Jaap
Publicado 2022

Expression of Cancer Testis Antigens in Tumor-Adjacent Normal Liver Is Associated with Post-Resection Recurrence of Hepatocellular Carcinoma

por Noordam, Lisanne, Ge, Zhouhong, Özturk, Hadiye, Doukas, Michail, Mancham, Shanta, Boor, Patrick P. C., Campos Carrascosa, Lucia, Zhou, Guoying, van den Bosch, Thierry P. P., Pan, Qiuwei, IJzermans, Jan N. M., Bruno, Marco J., Sprengers, Dave, Kwekkeboom, Jaap
Publicado 2021

Activated CD4(+) T Cells and Highly Differentiated Alloreactive CD4(+) T Cells Distinguish Operationally Tolerant Liver Transplantation Recipients

por Duizendstra, Aafke A., de Knegt, Robert J., Mancham, Shanta, Klepper, Mariska, Roelen, Dave L., Brand‐Schaaf, Simone H., Boor, Patrick P., Doukas, Michail, de Man, Robert A., Sprengers, Dave, Peppelenbosch, Maikel P., Betjes, Michiel G. H., Kwekkeboom, Jaap, Litjens, Nicolle H. R.
Publicado 2021

Blockade of LAG3 enhances responses of tumor-infiltrating T cells in mismatch repair-proficient liver metastases of colorectal cancer

por Zhou, Guoying, Noordam, Lisanne, Sprengers, Dave, Doukas, Michail, Boor, Patrick P. C., van Beek, Adriaan A., Erkens, Remco, Mancham, Shanta, Grünhagen, Dirk, Menon, Anand G., Lange, Johan F., Burger, Pim J. W. A., Brandt, Alexandra, Galjart, Boris, Verhoef, Cornelis, Kwekkeboom, Jaap, Bruno, Marco J.
Publicado 2018

TIGIT and PD1 Co-blockade Restores ex vivo Functions of Human Tumor-Infiltrating CD8(+) T Cells in Hepatocellular Carcinoma

por Ge, Zhouhong, Zhou, Guoying, Campos Carrascosa, Lucia, Gausvik, Erik, Boor, Patrick P.C., Noordam, Lisanne, Doukas, Michael, Polak, Wojciech G., Terkivatan, Türkan, Pan, Qiuwei, Takkenberg, R. Bart, Verheij, Joanne, Erdmann, Joris I., IJzermans, Jan N.M., Peppelenbosch, Maikel P., Kraan, Jaco, Kwekkeboom, Jaap, Sprengers, Dave
Publicado 2021

Immunopeptidome of hepatocytes isolated from patients with HBV infection and hepatocellular carcinoma

por de Beijer, Monique T.A., Bezstarosti, Karel, Luijten, Robbie, Doff, Wouter A.S., Boor, Patrick P.C., Pieterman, Roel F.A., Bouzid, Rachid, Biesta, Paula J., Ijzermans, Jan N.M., Doukas, Michail, de Man, Robert A., Woltman, Andrea M., Demmers, Jeroen A.A., Buschow, Sonja I.
Publicado 2022

GITR ligation enhances functionality of tumor‐infiltrating T cells in hepatocellular carcinoma

por van Beek, Adriaan A., Zhou, Guoying, Doukas, Michail, Boor, Patrick P.C., Noordam, Lisanne, Mancham, Shanta, Campos Carrascosa, Lucia, van der Heide‐Mulder, Marieke, Polak, Wojciech G., Ijzermans, Jan N.M., Pan, Qiuwei, Heirman, Carlo, Mahne, Ashley, Bucktrout, Samantha L., Bruno, Marco J., Sprengers, Dave, Kwekkeboom, Jaap
Publicado 2019

Modelling immune cytotoxicity for cholangiocarcinoma with tumour-derived organoids and effector T cells

por Zhou, Guoying, Lieshout, Ruby, van Tienderen, Gilles S., de Ruiter, Valeska, van Royen, Martin E., Boor, Patrick P. C., Magré, Luc, Desai, Jyaysi, Köten, Kübra, Kan, Yik Yang, Ge, Zhouhong, Campos Carrascosa, Lucia, Geuijen, Cecile, Sprengers, Dave, van der Laan, Luc J. W., Verstegen, Monique M. A., Kwekkeboom, Jaap
Publicado 2022

PD-L1, Galectin-9 and CD8(+) tumor-infiltrating lymphocytes are associated with survival in hepatocellular carcinoma

por Sideras, Kostandinos, Biermann, Katharina, Verheij, Joanne, Takkenberg, Bart R., Mancham, Shanta, Hansen, Bettina E., Schutz, Hannah M., de Man, Robert A., Sprengers, Dave, Buschow, Sonja I., Verseput, Maddy C. M., Boor, Patrick P. C., Pan, Qiuwei, van Gulik, Thomas M., Terkivatan, Turkan, Ijzermans, Jan N. M., Beuers, Ulrich H. W., Sleijfer, Stefan, Bruno, Marco J., Kwekkeboom, Jaap
Publicado 2017

FcγRIIB engagement drives agonistic activity of Fc-engineered αOX40 antibody to stimulate human tumor-infiltrating T cells

por Campos Carrascosa, Lucia, van Beek, Adriaan A, de Ruiter, Valeska, Doukas, Michail, Wei, Jie, Fisher, Timothy S, Ching, Keith, Yang, Wenjing, van Loon, Karlijn, Boor, Patrick P C, Rakké, Yannick S, Noordam, Lisanne, Doornebosch, Pascal, Grünhagen, Dirk, Verhoef, Kees, Polak, Wojciech G, IJzermans, Jan N M, Ni, Irene, Yeung, Yik Andy, Salek-Ardakani, Shahram, Sprengers, Dave, Kwekkeboom, Jaap
Publicado 2020