Ap4 is rate limiting for intestinal tumor formation by controlling the homeostasis of intestinal stem cells

por Jaeckel, Stephanie, Kaller, Markus, Jackstadt, Rene, Götz, Ursula, Müller, Susanna, Boos, Sophie, Horst, David, Jung, Peter, Hermeking, Heiko
Publicado 2018

Targeting c-MYC through Interference with NAMPT and SIRT1 and Their Association to Oncogenic Drivers in Murine Serrated Intestinal Tumorigenesis()

por Brandl, Lydia, Zhang, Yina, Kirstein, Nina, Sendelhofert, Andrea, Boos, Sophie Luise, Jung, Peter, Greten, Florian, Rad, Roland, Menssen, Antje
Publicado 2019

Oncogenic KRas-induced Increase in Fluid-phase Endocytosis is Dependent on N-WASP and is Required for the Formation of Pancreatic Preneoplastic Lesions

por Lubeseder-Martellato, Clara, Alexandrow, Katharina, Hidalgo-Sastre, Ana, Heid, Irina, Boos, Sophie Luise, Briel, Thomas, Schmid, Roland M., Siveke, Jens T.
Publicado 2016

Wnt-driven LARGE2 mediates laminin-adhesive O-glycosylation in human colonic epithelial cells and colorectal cancer

por Dietinger, Vanessa, García de Durango, Cira R., Wiechmann, Svenja, Boos, Sophie L., Michl, Marlies, Neumann, Jens, Hermeking, Heiko, Kuster, Bernhard, Jung, Peter
Publicado 2020

Proimmunogenic impact of MEK inhibition synergizes with agonist anti-CD40 immunostimulatory antibodies in tumor therapy

por Baumann, Daniel, Hägele, Tanja, Mochayedi, Julian, Drebant, Jennifer, Vent, Caroline, Blobner, Sven, Noll, Julia Han, Nickel, Irena, Schumacher, Corinna, Boos, Sophie Luise, Daniel, Aline Sophie, Wendler, Susann, Volkmar, Michael, Strobel, Oliver, Offringa, Rienk
Publicado 2020

Disease Modeling on Tumor Organoids Implicates AURKA as a Therapeutic Target in Liver Metastatic Colorectal Cancer

por Boos, Sophie L., Loevenich, Leon P., Vosberg, Sebastian, Engleitner, Thomas, Öllinger, Rupert, Kumbrink, Jörg, Rokavec, Matjaz, Michl, Marlies, Greif, Philipp A., Jung, Andreas, Hermeking, Heiko, Neumann, Jens, Kirchner, Thomas, Rad, Roland, Jung, Peter
Publicado 2021