Cytochrome P450 3A4, 3A5, and 2C8 expression in breast, prostate, lung, endometrial, and ovarian tumors: relevance for resistance to taxanes

por van Eijk, Maarten, Boosman, René J., Schinkel, Alfred H., Huitema, Alwin D. R., Beijnen, Jos H.
Publicado 2019

Highly sensitive quantification of pemetrexed in human plasma using UPLC‐MS/MS to support microdosing studies

por van Ewijk‐Beneken Kolmer, Eleonora W. J., Teulen, Marga J. A., Boosman, Rene J., de Rouw, Nikki, Burgers, Jacobus A., ter Heine, Rob
Publicado 2021

Ritonavir-Boosted Exposure of Kinase Inhibitors: an Open Label, Cross-over Pharmacokinetic Proof-of-Concept Trial with Erlotinib

por Boosman, René J., de Gooijer, Cornedine J., Groenland, Stefanie L., Burgers, Jacobus A., Baas, Paul, van der Noort, Vincent, Beijnen, Jos H., Huitema, Alwin D.R., Steeghs, Neeltje
Publicado 2022

Rethinking the Application of Pemetrexed for Patients with Renal Impairment: A Pharmacokinetic Analysis

por de Rouw, Nikki, Boosman, Rene J., Huitema, Alwin D. R., Hilbrands, Luuk B., Svensson, Elin M., Derijks, Hieronymus J., van den Heuvel, Michel M., Burger, David M., ter Heine, Rob
Publicado 2021

The Pharmacoeconomic Benefits of Pemetrexed Dose Individualization in Patients With Lung Cancer

por de Rouw, Nikki, de Boer, Merel, Boosman, René J., van den Heuvel, Michel M., Burger, David M., Lieverse, Joris E., Derijks, Hieronymus J., Frederix, Geert W.J., ter Heine, Rob
Publicado 2022

Renal function-based versus standard dosing of pemetrexed: a randomized controlled trial

por de Rouw, Nikki, Boosman, René J., Burgers, Jacobus A., Huitema, Alwin D. R., Dingemans, Anne-Marie C., Derijks, Hieronymus. J., Burger, David M., Piet, Berber, Hendriks, Lizza E. L., Biesma, Bonne, Pruis, Melinda A., Dumoulin, Daphne W., Croes, Sander, Mathijssen, Ron H. J., van den Heuvel, Michel M., ter Heine, Rob
Publicado 2022

Influence of germline variations in drug transporters ABCB1 and ABCG2 on intracerebral osimertinib efficacy in patients with non-small cell lung cancer

por Veerman, G.D. Marijn, Boosman, Rene J., Jebbink, Merel, Oomen-de Hoop, Esther, van der Wekken, Anthonie J., Bahce, Idris, Hendriks, Lizza E.L., Croes, Sander, Steendam, Christi M.J., de Jonge, Evert, Koolen, Stijn L.W., Steeghs, Neeltje, van Schaik, Ron H.N., Smit, Egbert F., Dingemans, Anne-Marie C., Huitema, Alwin D.R., Mathijssen, Ron H.J.
Publicado 2023

Hyperhydration with cisplatin does not influence pemetrexed exposure

por de Rouw, Nikki, Derijks, Hieronymus J., Hilbrands, Luuk B., Boosman, René J., Piet, Berber, Koolen, Stijn L. W., Burgers, Jacobus A., Dingemans, Anne‐Marie C., van den Heuvel, Michel M., Hendriks, Lizza E. L., Aerts, Joachim G. J. V., Croes, Sander, Mathijssen, Ron H. J., Huitema, Alwin D. R., Burger, David M., Biesma, Bonne, ter Heine, Rob
Publicado 2021