A rare case of sporadic mismatch repair deficient pancreatic ductal adenocarcinoma that responded to ipilimumab and nivolumab combination treatment: case report

por Han, Margaret Y., Borazanci, Erkut
Publicado 2023

Malignant ascites in pancreatic cancer: Pathophysiology, diagnosis, molecular characterization, and therapeutic strategies

por Han, Margaret Y., Borazanci, Erkut H.
Publicado 2023

Mitomycin C in Homologous Recombination Deficient Metastatic Pancreatic Cancer after Disease Progression on Platinum-Based Chemotherapy and Olaparib

por Botrus, Gehan, Roe, Denise, Jameson, Gayle S., Junior, Pedro Luiz Serrano Uson, Korn, Ronald Lee, Caldwell, Lana, Bargenquast, Taylor, Miller, Max, Borazanci, Erkut Hasan
Publicado 2022

The value of comprehensive genomic sequencing to maximize the identification of clinically actionable alterations in advanced cancer patients: a case series

por Drenner, Kevin, Basu, Gargi D., Goodman, Laurie J., Ozols, Audrey A., LoBello, Janine R., Royce, Thomas, Gordon, Michael S., Borazanci, Erkut H., Steinbach, Margaux A., Trent, Jeffrey, Sharma, Sunil
Publicado 2021

Addendum: The value of comprehensive genomic sequencing to maximize the identification of clinically actionable alterations in advanced cancer patients: a case series

por Drenner, Kevin, Basu, Gargi D., Goodman, Laurie J., Ozols, Audrey A., LoBello, Janine R., Royce, Thomas, Gordon, Michael S., Borazanci, Erkut H., Steinbach, Margaux A., Trent, Jeffrey, Sharma, Sunil
Publicado 2022

Overcoming Taxane Resistance: Preclinical and Phase 1 Studies of Relacorilant, a Selective Glucocorticoid Receptor Modulator, with Nab-Paclitaxel in Solid Tumors

por Munster, Pamela N., Greenstein, Andrew E., Fleming, Gini F., Borazanci, Erkut, Sharma, Manish R., Custodio, Joseph M., Tudor, Iulia Cristina, Pashova, Hristina I., Shepherd, Stacie Peacock, Grauer, Andreas, Sachdev, Jasgit C.
Publicado 2022

Role of 3D Volumetric and Perfusion Imaging for Detecting Early Changes in Pancreatic Adenocarcinoma

por Rahmanuddin, Syed, Korn, Ronald, Cridebring, Derek, Borazanci, Erkut, Brase, Jordyn, Boswell, William, Jamil, Asma, Cai, Wenli, Sabir, Aqsa, Motarjem, Pejman, Koay, Eugene, Mitra, Anirban, Goel, Ajay, Ho, Joyce, Chung, Vincent, Von Hoff, Daniel D.
Publicado 2021

Single-cell transcriptome analysis of tumor and stromal compartments of pancreatic ductal adenocarcinoma primary tumors and metastatic lesions

por Lin, Wei, Noel, Pawan, Borazanci, Erkut H., Lee, Jeeyun, Amini, Albert, Han, In Woong, Heo, Jin Seok, Jameson, Gayle S., Fraser, Cory, Steinbach, Margaux, Woo, Yanghee, Fong, Yuman, Cridebring, Derek, Von Hoff, Daniel D., Park, Joon Oh, Han, Haiyong
Publicado 2020

First-in-human study of the safety, pharmacokinetics, and pharmacodynamics of first-in-class fatty acid synthase inhibitor TVB-2640 alone and with a taxane in advanced tumors

por Falchook, Gerald, Infante, Jeffrey, Arkenau, Hendrik-Tobias, Patel, Manish R., Dean, Emma, Borazanci, Erkut, Brenner, Andrew, Cook, Natalie, Lopez, Juanita, Pant, Shubham, Frankel, Arthur, Schmid, Peter, Moore, Kathleen, McCulloch, William, Grimmer, Katharine, O'Farrell, Marie, Kemble, George, Burris, Howard
Publicado 2021

Safety and activity of the TGFβ receptor I kinase inhibitor galunisertib plus the anti-PD-L1 antibody durvalumab in metastatic pancreatic cancer

por Melisi, Davide, Oh, Do-Youn, Hollebecque, Antoine, Calvo, Emiliano, Varghese, Anna, Borazanci, Erkut, Macarulla, Teresa, Merz, Valeria, Zecchetto, Camilla, Zhao, Yumin, Gueorguieva, Ivelina, Man, Michael, Gandhi, Leena, Estrem, Shawn T, Benhadji, Karim A, Lanasa, Mark C, Avsar, Emin, Guba, Susan C, Garcia-Carbonero, Rocio
Publicado 2021

A Preclinical and Phase Ib Study of Palbociclib plus Nab-Paclitaxel in Patients with Metastatic Adenocarcinoma of the Pancreas

por Hidalgo, Manuel, Garcia-Carbonero, Rocio, Lim, Kian-Huat, Messersmith, Wells A., Garrido-Laguna, Ignacio, Borazanci, Erkut, Lowy, Andrew M., Medina Rodriguez, Laura, Laheru, Daniel, Salvador-Barbero, Beatriz, Malumbres, Marcos, Shields, David J., Grossman, Joseph E., Huang, Xin, Tammaro, Meggan, Martini, Jean-François, Yu, Yanke, Kern, Kenneth, Macarulla, Teresa
Publicado 2022

An exploratory study of metformin with or without rapamycin as maintenance therapy after induction chemotherapy in patients with metastatic pancreatic adenocarcinoma

por Bever, Katherine M., Borazanci, Erkut H., Thompson, Elizabeth A., Durham, Jennifer N., Pinero, Kimberly, Jameson, Gayle S., Vrana, Amber, Liu, Meizheng, Wilt, Cara, Wu, Annie A., Fu, Wei, Wang, Hao, Yin, Yafu, Leal, Jeffrey P., Jesus-Acosta, Ana De, Zheng, Lei, Laheru, Daniel A., Von Hoff, Daniel D., Jaffee, Elizabeth M., Powell, Jonathan D., Le, Dung T.
Publicado 2020

Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring

por Shi, Yu, Gao, Weina, Lytle, Nikki K., Huang, Peiwu, Yuan, Xiao, Dann, Amanda M., Ridinger-Saison, Maya, DelGiorno, Kathleen E., Antal, Corina E., Liang, Gaoyang, Atkins, Annette R., Erikson, Galina, Sun, Huaiyu, Meisenhelder, Jill, Terenziani, Elena, Woo, Gyunghwi, Fang, Linjing, Santisakultarm, Thom P., Manor, Uri, Xu, Ruilian, Becerra, Carlos R., Borazanci, Erkut, Von Hoff, Daniel D., Grandgenett, Paul M., Hollingsworth, Michael A., Leblanc, Mathias, Umetsu, Sarah E., Collisson, Eric A., Scadeng, Miriam, Lowy, Andrew M., Donahue, Timothy R., Reya, Tannishtha, Downes, Michael, Evans, Ronald M., Wahl, Geoffrey M., Pawson, Tony, Tian, Ruijun, Hunter, Tony
Publicado 2019

A super-enhancer-regulated RNA-binding protein cascade drives pancreatic cancer

por Antal, Corina E., Oh, Tae Gyu, Aigner, Stefan, Luo, En-Ching, Yee, Brian A., Campos, Tania, Tiriac, Hervé, Rothamel, Katherine L., Cheng, Zhang, Jiao, Henry, Wang, Allen, Hah, Nasun, Lenkiewicz, Elizabeth, Lumibao, Jan C., Truitt, Morgan L., Estepa, Gabriela, Banayo, Ester, Bashi, Senada, Esparza, Edgar, Munoz, Ruben M., Diedrich, Jolene K., Sodir, Nicole M., Mueller, Jasmine R., Fraser, Cory R., Borazanci, Erkut, Propper, David, Von Hoff, Daniel D., Liddle, Christopher, Yu, Ruth T., Atkins, Annette R., Han, Haiyong, Lowy, Andrew M., Barrett, Michael T., Engle, Dannielle D., Evan, Gerard I., Yeo, Gene W., Downes, Michael, Evans, Ronald M.
Publicado 2023