Recombinant ASF Live Attenuated Virus Strains as Experimental Vaccine Candidates

por Gladue, Douglas P., Borca, Manuel V.
Publicado 2022

CRISPR-Cas9, a tool to efficiently increase the development of recombinant African swine fever viruses

por Borca, Manuel V., Holinka, Lauren G., Berggren, Keith A., Gladue, Douglas P.
Publicado 2018

The Role of Interleukin 6 During Viral Infections

por Velazquez-Salinas, Lauro, Verdugo-Rodriguez, Antonio, Rodriguez, Luis L., Borca, Manuel V.
Publicado 2019

Morphologic and phenotypic characteristics of myocarditis in two pigs infected by foot-and mouth disease virus strains of serotypes O or A

por Stenfeldt, Carolina, Pacheco, Juan M, Borca, Manuel V, Rodriguez, Luis L, Arzt, Jonathan
Publicado 2014

A Triple Gene-Deleted Pseudorabies Virus-Vectored Subunit PCV2b and CSFV Vaccine Protect Pigs against a Virulent CSFV Challenge

por Silva, Ediane, Medina-Ramirez, Elizabeth, Pavulraj, Selvaraj, Gladue, Douglas P., Borca, Manuel, Chowdhury, Shafiqul I.
Publicado 2023

Positive Selection of ORF1ab, ORF3a, and ORF8 Genes Drives the Early Evolutionary Trends of SARS-CoV-2 During the 2020 COVID-19 Pandemic

por Velazquez-Salinas, Lauro, Zarate, Selene, Eberl, Samantha, Gladue, Douglas P., Novella, Isabel, Borca, Manuel V.
Publicado 2020

Optimization in the expression of ASFV proteins for the development of subunit vaccines using poxviruses as delivery vectors

por Lopera-Madrid, Jaime, Medina-Magües, Lex G., Gladue, Douglas P., Borca, Manuel V., Osorio, Jorge E.
Publicado 2021

Development of Porcine Monoclonal Antibodies with In Vitro Neutralizing Activity against Classical Swine Fever Virus from C-Strain E2-Specific Single B Cells

por Wang, Lihua, Madera, Rachel, Li, Yuzhen, Gladue, Douglas P., Borca, Manuel V., McIntosh, Michael T., Shi, Jishu
Publicado 2023

Mechanisms of African swine fever virus pathogenesis and immune evasion inferred from gene expression changes in infected swine macrophages

por Zhu, James J., Ramanathan, Palaniappan, Bishop, Elizabeth A., O’Donnell, Vivian, Gladue, Douglas P., Borca, Manuel V.
Publicado 2019

ASF Vaccine Candidate ASFV-G-∆I177L Does Not Exhibit Residual Virulence in Long-Term Clinical Studies

por Borca, Manuel V., Ramirez-Medina, Elizabeth, Silva, Ediane, Rai, Ayushi, Espinoza, Nallely, Velazquez-Salinas, Lauro, Gladue, Douglas P.
Publicado 2023

Interaction of Structural Glycoprotein E2 of Classical Swine Fever Virus with Protein Phosphatase 1 Catalytic Subunit Beta (PPP1CB)

por Vuono, Elizabeth A., Ramirez-Medina, Elizabeth, Holinka, Lauren G., Baker-Branstetter, Ryan, Borca, Manuel V., Gladue, Douglas P.
Publicado 2019

Classical Swine Fever Virus Structural Glycoprotein E2 Interacts with Host Protein ACADM during the Virus Infectious Cycle

por Vuono, Elizabeth, Ramirez-Medina, Elizabeth, Silva, Ediane, Berggren, Keith, Rai, Ayushi, Espinoza, Nallely, Gladue, Douglas P., Borca, Manuel V.
Publicado 2023

Serum Neutralizing and Enhancing Effects on African Swine Fever Virus Infectivity in Adherent Pig PBMC

por Canter, Jessica A., Aponte, Theresa, Ramirez-Medina, Elizabeth, Pruitt, Sarah, Gladue, Douglas P., Borca, Manuel V., Zhu, James J.
Publicado 2022

Complete Structural Predictions of the Proteome of African Swine Fever Virus Strain Georgia 2007

por Spinard, Edward, Azzinaro, Paul, Rai, Ayushi, Espinoza, Nallely, Ramirez-Medina, Elizabeth, Valladares, Alyssa, Borca, Manuel V., Gladue, Douglas P.
Publicado 2022

Deletion of the H240R Gene in African Swine Fever Virus Partially Reduces Virus Virulence in Swine

por Ramirez-Medina, Elizabeth, Rai, Ayushi, Espinoza, Nallely, Valladares, Alyssa, Silva, Ediane, Velazquez-Salinas, Lauro, Borca, Manuel V., Gladue, Douglas P.
Publicado 2023

Development of a fluorescent ASFV strain that retains the ability to cause disease in swine

por Borca, Manuel V., O’Donnell, Vivian, Holinka, Lauren G., Sanford, Brent, Azzinaro, Paul A., Risatti, Guillermo R., Gladue, Douglas P.
Publicado 2017

A Re-Evaluation of African Swine Fever Genotypes Based on p72 Sequences Reveals the Existence of Only Six Distinct p72 Groups

por Spinard, Edward, Dinhobl, Mark, Tesler, Nicolas, Birtley, Hillary, Signore, Anthony V., Ambagala, Aruna, Masembe, Charles, Borca, Manuel V., Gladue, Douglas P.
Publicado 2023

Foot-and-mouth disease virus utilizes an autophagic pathway during viral replication

por O'Donnell, Vivian, Pacheco, Juan M., LaRocco, Michael, Burrage, Tom, Jackson, William, Rodriguez, Luis L., Borca, Manuel V., Baxt, Barry
Publicado 2011

Evaluation of the Function of the ASFV KP177R Gene, Encoding for Structural Protein p22, in the Process of Virus Replication and in Swine Virulence

por Vuono, Elizabeth A., Ramirez-Medina, Elizabeth, Pruitt, Sarah, Rai, Ayushi, Espinoza, Nallely, Velazquez-Salinas, Lauro, Gladue, Douglas P., Borca, Manuel V.
Publicado 2021

Development Real-Time PCR Assays to Genetically Differentiate Vaccinated Pigs From Infected Pigs With the Eurasian Strain of African Swine Fever Virus

por Velazquez-Salinas, Lauro, Ramirez-Medina, Elizabeth, Rai, Ayushi, Pruitt, Sarah, Vuono, Elizabeth A., Espinoza, Nallely, Gladue, Douglas P., Borca, Manuel V.
Publicado 2021