Dissecting the dynamic transcriptional landscape of early T helper cell differentiation into Th1, Th2, and Th1/2 hybrid cells

por Burt, Philipp, Peine, Michael, Peine, Caroline, Borek, Zuzanna, Serve, Sebastian, Floßdorf, Michael, Hegazy, Ahmed N., Höfer, Thomas, Löhning, Max, Thurley, Kevin
Publicado 2022

Systematic Prioritization of Candidate Genes in Disease Loci Identifies TRAFD1 as a Master Regulator of IFNγ Signaling in Celiac Disease

por van der Graaf, Adriaan, Zorro, Maria M., Claringbould, Annique, Võsa, Urmo, Aguirre-Gamboa, Raúl, Li, Chan, Mooiweer, Joram, Ricaño-Ponce, Isis, Borek, Zuzanna, Koning, Frits, Kooy-Winkelaar, Yvonne, Sollid, Ludvig M., Qiao, Shuo-Wang, Kumar, Vinod, Li, Yang, Franke, Lude, Withoff, Sebo, Wijmenga, Cisca, Sanna, Serena, Jonkers, Iris
Publicado 2021

Potential impact of celiac disease genetic risk factors on T cell receptor signaling in gluten-specific CD4+ T cells

por Bakker, Olivier B., Ramírez-Sánchez, Aarón D., Borek, Zuzanna A., de Klein, Niek, Li, Yang, Modderman, Rutger, Kooy-Winkelaar, Yvonne, Johannesen, Marie K., Matarese, Filomena, Martens, Joost H. A., Kumar, Vinod, van Bergen, Jeroen, Qiao, Shuo-Wang, Lundin, Knut E. A., Sollid, Ludvig M., Koning, Frits, Wijmenga, Cisca, Withoff, Sebo, Jonkers, Iris H.
Publicado 2021

Refined mapping of autoimmune disease associated genetic variants with gene expression suggests an important role for non-coding RNAs

por Ricaño-Ponce, Isis, Zhernakova, Daria V., Deelen, Patrick, Luo, Oscar, Li, Xingwang, Isaacs, Aaron, Karjalainen, Juha, Di Tommaso, Jennifer, Borek, Zuzanna Agnieszka, Zorro, Maria M., Gutierrez-Achury, Javier, Uitterlinden, Andre G., Hofman, Albert, van Meurs, Joyce, Netea, Mihai G., Jonkers, Iris H., Withoff, Sebo, van Duijn, Cornelia M., Li, Yang, Ruan, Yijun, Franke, Lude, Wijmenga, Cisca, Kumar, Vinod
Publicado 2016

Deconvolution of bulk blood eQTL effects into immune cell subpopulations

por Aguirre-Gamboa, Raúl, de Klein, Niek, di Tommaso, Jennifer, Claringbould, Annique, van der Wijst, Monique GP, de Vries, Dylan, Brugge, Harm, Oelen, Roy, Võsa, Urmo, Zorro, Maria M., Chu, Xiaojin, Bakker, Olivier B., Borek, Zuzanna, Ricaño-Ponce, Isis, Deelen, Patrick, Xu, Cheng-Jiang, Swertz, Morris, Jonkers, Iris, Withoff, Sebo, Joosten, Irma, Sanna, Serena, Kumar, Vinod, Koenen, Hans J. P. M., Joosten, Leo A. B., Netea, Mihai G., Wijmenga, Cisca, Franke, Lude, Li, Yang
Publicado 2020