PIK3CA activating mutations are associated with more disseminated disease at presentation and earlier recurrence in glioblastoma

por Tanaka, Shota, Batchelor, Tracy T., Iafrate, A. John, Dias-Santagata, Dora, Borger, Darrell R., Ellisen, Leif W., Yang, Daniel, Louis, David N., Cahill, Daniel P., Chi, Andrew S.
Publicado 2019

Epigenetic regulation of CD133 and tumorigenicity of CD133 positive and negative endometrial cancer cells

por Friel, Anne M, Zhang, Ling, Curley, Michael D, Therrien, Vanessa A, Sergent, Petra A, Belden, Sarah E, Borger, Darrell R, Mohapatra, Gayatry, Zukerberg, Lawrence R, Foster, Rosemary, Rueda, Bo R
Publicado 2010

BRAF V600E Mutations Are Common in Pleomorphic Xanthoastrocytoma: Diagnostic and Therapeutic Implications

por Dias-Santagata, Dora, Lam, Quynh, Vernovsky, Kathy, Vena, Natalie, Lennerz, Jochen K., Borger, Darrell R., Batchelor, Tracy T., Ligon, Keith L., Iafrate, A. John, Ligon, Azra H., Louis, David N., Santagata, Sandro
Publicado 2011

Synergistic Effects of Targeted PI3K Signaling Inhibition and Chemotherapy in Liposarcoma

por Guo, Shang, Lopez-Marquez, Hector, Fan, Kenneth C., Choy, Edwin, Cote, Gregory, Harmon, David, Nielsen, G. Petur, Yang, Cao, Zhang, Changqing, Mankin, Henry, Hornicek, Francis J., Borger, Darrell R., Duan, Zhenfeng
Publicado 2014

Primary tumor sidedness is an independent prognostic marker for survival in metastatic colorectal cancer: Results from a large retrospective cohort with mutational analysis

por Kamran, Sophia C., Clark, Jeffrey W., Zheng, Hui, Borger, Darrell R., Blaszkowsky, Lawrence S., Allen, Jill N., Kwak, Eunice L., Wo, Jennifer Y., Parikh, Aparna R., Nipp, Ryan D., Murphy, Janet E., Goyal, Lipika, Zhu, Andrew X., Iafrate, A. John, Corcoran, Ryan B., Ryan, David P., Hong, Theodore S.
Publicado 2018

Inhibition of Hedgehog Signaling Antagonizes Serous Ovarian Cancer Growth in a Primary Xenograft Model

por McCann, Christopher K., Growdon, Whitfield B., Kulkarni-Datar, Kashmira, Curley, Michael D., Friel, Anne M., Proctor, Jennifer L., Sheikh, Hana, Deyneko, Igor, Ferguson, Jeanne A., Vathipadiekal, Vinod, Birrer, Michael J., Borger, Darrell R., Mohapatra, Gayatry, Zukerberg, Lawrence R., Foster, Rosemary, MacDougall, John R., Rueda, Bo R.
Publicado 2011

Rapid targeted mutational analysis of human tumours: a clinical platform to guide personalized cancer medicine

por Dias-Santagata, Dora, Akhavanfard, Sara, David, Serena S, Vernovsky, Kathy, Kuhlmann, Georgiana, Boisvert, Susan L, Stubbs, Hannah, McDermott, Ultan, Settleman, Jeffrey, Kwak, Eunice L, Clark, Jeffrey W, Isakoff, Steven J, Sequist, Lecia V, Engelman, Jeffrey A, Lynch, Thomas J, Haber, Daniel A, Louis, David N, Ellisen, Leif W, Borger, Darrell R, Iafrate, A John
Publicado 2010

RB loss in resistant EGFR mutant lung adenocarcinomas that transform to small-cell lung cancer

por Niederst, Matthew J., Sequist, Lecia V., Poirier, John T., Mermel, Craig H., Lockerman, Elizabeth L., Garcia, Angel R., Katayama, Ryohei, Costa, Carlotta, Ross, Kenneth N., Moran, Teresa, Howe, Emily, Fulton, Linnea E., Mulvey, Hillary E., Bernardo, Lindsay A., Mohamoud, Farhiya, Miyoshi, Norikatsu, VanderLaan, Paul A., Costa, Daniel B., Jänne, Pasi A., Borger, Darrell R., Ramaswamy, Sridhar, Shioda, Toshi, Iafrate, Anthony J., Getz, Gad, Rudin, Charles M., Mino-Kenudson, Mari, Engelman, Jeffrey A.
Publicado 2015

Genomic characterization of human brain metastases identifies drivers of metastatic lung adenocarcinoma

por Shih, David J. H., Nayyar, Naema, Bihun, Ivanna, Dagogo-Jack, Ibiayi, Gill, Corey M., Aquilanti, Elisa, Bertalan, Mia, Kaplan, Alexander, D’Andrea, Megan R., Chukwueke, Ugonma, Ippen, Franziska Maria, Alvarez-Breckenridge, Christopher, Camarda, Nicholas D., Lastrapes, Matthew, McCabe, Devin, Kuter, Ben, Kaufman, Benjamin, Strickland, Matthew R., Martinez-Gutierrez, Juan Carlos, Nagabhushan, Deepika, De Sauvage, Magali, White, Michael D., Castro, Brandyn A., Hoang, Kaitlin, Kaneb, Andrew, Batchelor, Emily D., Paek, Sun Ha, Park, Sun Hye, Martinez-Lage, Maria, Berghoff, Anna S., Merrill, Parker, Gerstner, Elizabeth R., Batchelor, Tracy T., Frosch, Matthew P., Frazier, Ryan P., Borger, Darrell R., Iafrate, A. John, Johnson, Bruce E., Santagata, Sandro, Preusser, Matthias, Cahill, Daniel P., Carter, Scott L., Brastianos, Priscilla K.
Publicado 2020