Human Mitochondrial Hsp70 (Mortalin): Shedding Light on ATPase Activity, Interaction with Adenosine Nucleotides, Solution Structure and Domain Organization

por Dores-Silva, Paulo R., Barbosa, Leandro R. S., Ramos, Carlos H. I., Borges, Júlio C.
Publicado 2015

Central domain deletions affect the SAXS solution structure and function of Yeast Hsp40 proteins Sis1 and Ydj1

por Silva, Julio C, Borges, Julio C, Cyr, Douglas M, Ramos, Carlos HI, Torriani, Iris L
Publicado 2011

Interaction of HSPA5 (Grp78, BIP) with negatively charged phospholipid membranes via oligomerization involving the N-terminal end domain

por Dores-Silva, Paulo Roberto, Cauvi, David M., Coto, Amanda L. S., Kiraly, Vanessa T. R., Borges, Júlio C., De Maio, Antonio
Publicado 2020

Human heat shock cognate protein (HSC70/HSPA8) interacts with negatively charged phospholipids by a different mechanism than other HSP70s and brings HSP90 into membranes

por Dores-Silva, Paulo R., Cauvi, David M., Coto, Amanda L. S., Silva, Noeli S. M., Borges, Júlio C., De Maio, Antonio
Publicado 2021

Solution structure of the human signaling protein RACK1

por Gonçalves, Kaliandra A, Borges, Julio C, Silva, Julio C, Papa, Priscila F, Bressan, Gustavo C, Torriani, Iris L, Kobarg, Jörg
Publicado 2010

Identification of Regions Involved in Substrate Binding and Dimer Stabilization within the Central Domains of Yeast Hsp40 Sis1

por Borges, Júlio C., Seraphim, Thiago V., Mokry, David Z., Almeida, Fabio C. L., Cyr, Douglas M., Ramos, Carlos H. I.
Publicado 2012

Discovery of small molecule inhibitors of Leishmania braziliensis Hsp90 chaperone

por Batista, Fernanda A. H., Ramos, Sérgio L., Tassone, Giusy, Leitão, Andrei, Montanari, Carlos A., Botta, Maurizio, Mori, Mattia, Borges, Júlio C.
Publicado 2020

Synthesis and anti-HSV-1 evaluation of new 3H-benzo[b]pyrazolo[3,4-h]-1,6-naphthyridines and 3H-pyrido[2,3-b]pyrazolo[3,4-h]-1,6-naphthyridines

por Bernardino, Alice MR, Azevedo, Alexandre R, Pinheiro, Luiz CS, Borges, Júlio C, Paixão, Izabel CP, Mesquita, Milene, Souza, Thiago ML, dos Santos, Maurício S
Publicado 2012

Low Resolution Structural Studies Indicate that the Activator of Hsp90 ATPase 1 (Aha1) of Leishmania braziliensis Has an Elongated Shape Which Allows Its Interaction with Both N- a...

por Seraphim, Thiago V., Alves, Marina M., Silva, Indjara M., Gomes, Francisco E. R., Silva, Kelly P., Murta, Silvane M. F., Barbosa, Leandro R. S., Borges, Júlio C.
Publicado 2013

Possible Involvement of Hsp90 in the Regulation of Telomere Length and Telomerase Activity During the Leishmania amazonensis Developmental Cycle and Population Proliferation

por de Oliveira, Beatriz C. D., Shiburah, Mark E., Paiva, Stephany C., Vieira, Marina R., Morea, Edna Gicela O., da Silva, Marcelo Santos, Alves, Cristiane de Santis, Segatto, Marcela, Gutierrez-Rodrigues, Fernanda, Borges, Júlio C., Calado, Rodrigo T., Cano, Maria Isabel N.
Publicado 2021

Corrigendum: Possible Involvement of Hsp90 in the Regulation of Telomere Length and Telomerase Activity During the Leishmania Amazonensis Developmental Cycle and Population Prolife...

por de Oliveira, Beatriz C. D., Shiburah, Mark E., Paiva, Stephany C., Vieira, Marina R., Morea, Edna Gicela O., da Silva, Marcelo Santos, Alves, Cristiane de Santis, Segatto, Marcela, Gutierrez-Rodrigues, Fernanda, Borges, Júlio C., Calado, Rodrigo T., Cano, Maria Isabel N.
Publicado 2022

4-(1H-Pyrazol-1-yl) Benzenesulfonamide Derivatives: Identifying New Active Antileishmanial Structures for Use against a Neglected Disease

por Marra, Roberta K. F., Bernardino, Alice M. R., Proux, Tathiane A., Charret, Karen S., Lira, Marie-Luce F., Castro, Helena C., Souza, Alessandra M. T., Oliveira, Cesar D., Borges, Júlio C., Rodrigues, Carlos R., Canto-Cavalheiro, Marilene M., Leon, Leonor L., Amaral, Veronica F.
Publicado 2012