Das BRCA-like-Mammakarzinom profitiert von Cisplatin plus Veliparib; Ergebnisse der S1416-Phase-II-Studie

por Hintelmann, Katharina, Borgmann, Kerstin
Publicado 2023

Crosstalk between immune checkpoint and DNA damage response inhibitors for radiosensitization of tumors

por Classen, Sandra, Petersen, Cordula, Borgmann, Kerstin
Publicado 2023

Radiotherapeutic Strategies to Overcome Resistance of Breast Cancer Brain Metastases by Considering Immunogenic Aspects of Cancer Stem Cells

por Hintelmann, Katharina, Petersen, Cordula, Borgmann, Kerstin
Publicado 2022

Cancer Stem Cells and Radioresistance: DNA Repair and Beyond

por Schulz, Alexander, Meyer, Felix, Dubrovska, Anna, Borgmann, Kerstin
Publicado 2019

Molecular Mechanisms Associated with Brain Metastases in HER2-Positive and Triple Negative Breast Cancers

por Bryan, Sarah, Witzel, Isabell, Borgmann, Kerstin, Oliveira-Ferrer, Leticia
Publicado 2021

Beyond the Double-Strand Breaks: The Role of DNA Repair Proteins in Cancer Stem-Cell Regulation

por Nathansen, Jacqueline, Meyer, Felix, Müller, Luise, Schmitz, Marc, Borgmann, Kerstin, Dubrovska, Anna
Publicado 2021

The Intermediate Filament Synemin Regulates Non-Homologous End Joining in an ATM-Dependent Manner

por Deville, Sara Sofia, Vehlow, Anne, Förster, Sarah, Dickreuter, Ellen, Borgmann, Kerstin, Cordes, Nils
Publicado 2020

Cdc45 is limiting for replication initiation in humans

por Köhler, Carsten, Koalick, Dennis, Fabricius, Anja, Parplys, Ann Christin, Borgmann, Kerstin, Pospiech, Helmut, Grosse, Frank
Publicado 2016

5-Fluorouracil sensitizes colorectal tumor cells towards double stranded DNA breaks by interfering with homologous recombination repair

por Srinivas, Upadhyayula Sai, Dyczkowski, Jerzy, Beißbarth, Tim, Gaedcke, Jochen, Mansour, Wael Y., Borgmann, Kerstin, Dobbelstein, Matthias
Publicado 2015

Impaired 53BP1/RIF1 DSB mediated end-protection stimulates CtIP-dependent end resection and switches the repair to PARP1-dependent end joining in G1

por Bakr, Ali, Köcher, Sabrina, Volquardsen, Jennifer, Petersen, Cordula, Borgmann, Kerstin, Dikomey, Ekkehard, Rothkamm, Kai, Mansour, Wael Y.
Publicado 2016

Association of single nucleotide polymorphisms in the genes ATM, GSTP1, SOD2, TGFB1, XPD and XRCC1 with risk of severe erythema after breast conserving radiotherapy

por Raabe, Annette, Derda, Katharina, Reuther, Sebastian, Szymczak, Silke, Borgmann, Kerstin, Hoeller, Ulrike, Ziegler, Andreas, Petersen, Cordula, Dikomey, Ekkehard
Publicado 2012

TSC loss distorts DNA replication programme and sensitises cells to genotoxic stress

por Pai, Govind M., Zielinski, Alexandra, Koalick, Dennis, Ludwig, Kristin, Wang, Zhao-Qi, Borgmann, Kerstin, Pospiech, Helmut, Rubio, Ignacio
Publicado 2016

Biomarkers and Mechanisms of FANCD2 Function

por Willers, Henning, Kachnic, Lisa A., Luo, Chen-Mei, Li, Li, Purschke, Martin, Borgmann, Kerstin, Held, Kathryn D., Powell, Simon N.
Publicado 2008

Exploiting Chromosomal Instability of PTEN-Deficient Triple-Negative Breast Cancer Cell Lines for the Sensitization Against PARP1 Inhibition in a Replication-Dependent Manner

por Rieckhoff, Johanna, Meyer, Felix, Classen, Sandra, Zielinski, Alexandra, Riepen, Britta, Wikman, Harriet, Petersen, Cordula, Rothkamm, Kai, Borgmann, Kerstin, Parplys, Ann Christin
Publicado 2020

Efficient DNA Repair Mitigates Replication Stress Resulting in Less Immunogenic Cytosolic DNA in Radioresistant Breast Cancer Stem Cells

por Meyer, Felix, Engel, Anna Maria, Krause, Ann Kristin, Wagner, Tim, Poole, Lena, Dubrovska, Anna, Peitzsch, Claudia, Rothkamm, Kai, Petersen, Cordula, Borgmann, Kerstin
Publicado 2022

Clonogenicity-based radioresistance determines the expression of immune suppressive immune checkpoint molecules after hypofractionated irradiation of MDA-MB-231 triple-negative bre...

por Gehre, Simon, Meyer, Felix, Sengedorj, Azzaya, Grottker, Fridolin, Reichardt, Clara M., Alomo, Jannik, Borgmann, Kerstin, Frey, Benjamin, Fietkau, Rainer, Rückert, Michael, Gaipl, Udo S.
Publicado 2023

Hierarchy of nonhomologous end-joining, single-strand annealing and gene conversion at site-directed DNA double-strand breaks

por Mansour, Wael Y., Schumacher, Sabine, Rosskopf, Raphael, Rhein, Tim, Schmidt-Petersen, Filip, Gatzemeier, Fruszina, Haag, Friedrich, Borgmann, Kerstin, Willers, Henning, Dahm-Daphi, Jochen
Publicado 2008

Heterozygous mutations in PALB2 cause DNA replication and damage response defects

por Nikkilä, Jenni, Christin Parplys, Ann, Pylkäs, Katri, Bose, Muthiah, Huo, Yanying, Borgmann, Kerstin, Rapakko, Katrin, Nieminen, Pentti, Xia, Bing, Pospiech, Helmut, Winqvist, Robert
Publicado 2013

Constitutive gp130 activation rapidly accelerates the transformation of human hepatocytes via an impaired oxidative stress response

por Heim, Denise, Gil-Ibanez, Ines, Herden, Johannes, Parplys, Ann Christin, Borgmann, Kerstin, Schmidt-Arras, Dirk, Lohse, Ansgar W., Rose-John, Stefan, Wege, Henning
Publicado 2016

Oct4 confers stemness and radioresistance to head and neck squamous cell carcinoma by regulating the homologous recombination factors PSMC3IP and RAD54L

por Nathansen, Jacqueline, Lukiyanchuk, Vasyl, Hein, Linda, Stolte, Maya-Isabel, Borgmann, Kerstin, Löck, Steffen, Kurth, Ina, Baumann, Michael, Krause, Mechthild, Linge, Annett, Dubrovska, Anna
Publicado 2021